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Tissue Ablation With Excimer Laser and Multiple Fiber Catheters: Effects of Optical Fiber Density and Fluence

Tissue Ablation With Excimer Laser and Multiple Fiber Catheters: Effects of Optical Fiber Density... This study was performed to assess the ablational properties of 1.4‐, 1.7‐, and 2.0‐mm wire‐guided multiple fiber catheters coupled to a XeCl excimer laser. Samples of postmortem human aorta were irradiated in blood at fluences of 40, 50, and 60 mJ/mm2. Our results indicate that: 1) an increase in the active irradiation coverage results in an increase in the ablation efficiency; 2) the ablation efficiency is not fluence related using the 1.4‐ or 1.7‐mm multiple fiber catheter but efficiency is fluence dependent using the 2.0‐mm multiple fiber catheter; 3) the depth of tissue ablated with a multiple fiber catheter depends primarily upon the proportion of the active irradiation coverage at the catheter tip: 4) the 2.0‐mm multiple fiber catheter induces craters surrounded by a larger zone of tissue damage than that observed with the 1.4‐ or 1.7mm multiple fiber catheter; and 5) the 2.0‐mm multiple fiber catheter should be used cautiously for laser angioplasty because of its high penetration and its risk of arterial wall damage. (J Interven Cardiol 1992; 5:263–273) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Interventional Cardiology Wiley

Tissue Ablation With Excimer Laser and Multiple Fiber Catheters: Effects of Optical Fiber Density and Fluence

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References (22)

Publisher
Wiley
Copyright
Copyright © 1992 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0896-4327
eISSN
1540-8183
DOI
10.1111/j.1540-8183.1992.tb00831.x
Publisher site
See Article on Publisher Site

Abstract

This study was performed to assess the ablational properties of 1.4‐, 1.7‐, and 2.0‐mm wire‐guided multiple fiber catheters coupled to a XeCl excimer laser. Samples of postmortem human aorta were irradiated in blood at fluences of 40, 50, and 60 mJ/mm2. Our results indicate that: 1) an increase in the active irradiation coverage results in an increase in the ablation efficiency; 2) the ablation efficiency is not fluence related using the 1.4‐ or 1.7‐mm multiple fiber catheter but efficiency is fluence dependent using the 2.0‐mm multiple fiber catheter; 3) the depth of tissue ablated with a multiple fiber catheter depends primarily upon the proportion of the active irradiation coverage at the catheter tip: 4) the 2.0‐mm multiple fiber catheter induces craters surrounded by a larger zone of tissue damage than that observed with the 1.4‐ or 1.7mm multiple fiber catheter; and 5) the 2.0‐mm multiple fiber catheter should be used cautiously for laser angioplasty because of its high penetration and its risk of arterial wall damage. (J Interven Cardiol 1992; 5:263–273)

Journal

Journal of Interventional Cardiology – Wiley

Published: Dec 1, 1992

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