Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Alvarez, R. Gates, D. Rowe, P. Brady (1992)
Complications from intra-aortic balloon counterpulsation: a review of 303 cardiac surgical patients.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 6 10
Hirsh Hirsh, Anand Anand, Halperin Halperin (2001)
Guide to anticoagulant therapy: Heparin: A statement for healthcare professionals from the American Heart AssociationCirculation, 103
J. Mccabe, R. Abel, V. Subramanian, W. Gay (1978)
Complications of Intra-aortic Balloon Insertion and CounterpulsationCirculation, 57
G. Stone, E. Ohman, Michael Miller, D. Joseph, J. Christenson, Marc Cohen, P. Urban, R. Reddy, R. Freedman, Karen Staman, J. Ferguson (2003)
Contemporary utilization and outcomes of intra-aortic balloon counterpulsation in acute myocardial infarction: the benchmark registry.Journal of the American College of Cardiology, 41 11
J. Hirsh, Sonia Anand, J. Halperin, Fuster (2001)
AHA Scientific Statement: Guide to anticoagulant therapy: heparin: a statement for healthcare professionals from the American Heart Association.Arteriosclerosis, thrombosis, and vascular biology, 21 7
S. Yusuf, F. Zhao, S. Mehta, S. Chrolavicius, G. Tognoni, K. Fox, Clopidogrel Investigators (2001)
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation.The New England journal of medicine, 345 7
P. DiGiorgi, V. Rao, Y. Naka, M. Oz (2003)
Which patient, which pump?The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 22 3
Lancet, 348
A. Leo, S. Winteroll (2003)
Laboratory Diagnosis of Heparin-Induced Thrombocytopenia and Monitoring of Alternative AnticoagulantsClinical and Vaccine Immunology, 10
T. Warkentin (2003)
Heparin‐induced thrombocytopenia: pathogenesis and managementBritish Journal of Haematology, 121
Lancet, 356
C. Dietl, M. Berkheimer, E. Woods, C. Gilbert, William Pharr, Charles Benoit (1996)
Efficacy and cost-effectiveness of preoperative IABP in patients with ejection fraction of 0.25 or less.The Annals of thoracic surgery, 62 2
H. Dasgupta, J. Blankenship, G. Wood, C. Frey, S. Demko, F. Menapace (2000)
Thrombocytopenia complicating treatment with intravenous glycoprotein IIb/IIIa receptor inhibitors: a pooled analysis.American heart journal, 140 2
D. Clement (1996)
A randomised, blinded, trial of Clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)The Lancet, 348
Robert Vonderheide, Ravi Thadhani, David Kuter (1998)
Association of thrombocytopenia with the use of intra-aortic balloon pumps.The American journal of medicine, 105 1
Leo Leo, Winteroll Winteroll (2003)
Laboratory diagnosis of heparin‐induced thrombocytopenia and monitoring of alternative anticoagulantsClin Diagn Lab Immunol, 10
T. Warkentin, A. Greinacher (2004)
Heparin-induced thrombocytopenia: recognition, treatment, and prevention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.Chest, 126 3 Suppl
D. Paparella, A. Galeone, M. Micelli, C. Memmola, L. Schinosa (2004)
Early onset of heparin-induced thrombocytopenia with thrombosis after open heart surgery: importance of an early diagnosis and Lepirudin treatment.Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 15 2
D. Torchiana, Gregory Hirsch, Mortimer Buckley, Chiwon Hahn, John Allyn, Cary Akins, John Drake, John Newell, W. Austen (1997)
Intraaortic balloon pumping for cardiac support: trends in practice and outcome, 1968 to 1995.The Journal of thoracic and cardiovascular surgery, 113 4
B. Perler, C. McCabe, W. Abbott, M. Buckley (1983)
Vascular complications of intra-aortic balloon counterpulsation.Archives of surgery, 118 8
Christof Schmid, M. Wilhelm, A. Reimann, J. Rötker, M. Deiwick, M. Loick, S. Kerber, D. Hammel, Michael Weyand, H. Scheld (1999)
Use of an intraaortic balloon pump in patients with impaired left ventricular function.Scandinavian cardiovascular journal : SCJ, 33 4
Yusuf Yusuf, Zhao Zhao, Mehta Mehta (2001)
Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST‐segment elevationN Engl J Med, 345
J. Walls, T. Boley, J. Curtis, D. Silver (1992)
Heparin induced thrombocytopenia in patients undergoing intra-aortic balloon pumping after open heart surgery.ASAIO journal, 38 3
D. Brieger, K. Mak, K. Kottke-Marchant, E. Topol (1998)
Heparin-induced thrombocytopenia.Journal of the American College of Cardiology, 31 7
Helene Eltchaninoff, A. Dimas, P. Whitlow (1993)
Complications associated with percutaneous placement and use of intraaortic balloon counterpulsation.The American journal of cardiology, 71 4
M. Meco, G. Gramegna, A. Yassini, A. Bellisario, E. Mazzaro, M. Babbini, A. Pediglieri, P. Panisi, G. Tarelli, A. Frigiola, Lorenzo Menicanti, S. Cirri (2002)
Mortality and morbidity from intra-aortic balloon pumps. Risk analysis.The Journal of cardiovascular surgery, 43 1
Objectives: Determine the incidence and timing of intra‐aortic balloon pump (IABP)‐associated thrombocytopenia, if concomitant antiplatelet agents increase the incidence of thrombocytopenia, and the incidence of heparin‐induced thrombocytopenia (HIT) in a contemporary IABP population. Background: Previous studies predate the current practice of treating acute coronary syndrome patients with heparin and aspirin plus thienopyridines and glycoprotein IIb/IIIa receptor antagonists such that data are unavailable to determine if their co‐administration worsens IABP‐associated thrombocytopenia. Methods: A retrospective cohort study of adult IABP patients (n = 107) from 2002 to 2006 was performed to determine the indication for and duration of counterpulsation, platelet counts during and for 7 days postcounterpulsation, medications potentially contributing to thrombocytopenia, and HIT antibody results if obtained. Results: Thrombocytopenia, defined as platelets <150,000/mL or >50% decrease from baseline, occurred in 57.9% of patients. Overall, platelets declined to 60.2 ± 22.8% of baseline with the mean (± standard deviation) nadir on day 2.8 ± 2.0. Comparing patients who received heparin, aspirin, thienopyridines, and glycoprotein IIb/IIIa antagonists (n = 44) versus heparinized patients ± aspirin (n = 45), platelet nadirs were 62.7 ± 20.9% versus 58.3 ± 23.9% of baseline levels, respectively (P = 0.42). The incidence of HIT was 2.8% in the entire cohort. Conclusions: IABP‐associated thrombocytopenia occurred in 57.9% of this cohort. HIT was diagnosed in 2.8% and should be considered as a diagnosis if platelet counts do not stabilize or continue to fall after 3–4 days of counterpulsation. Increased use of antiplatelet therapy does not impact the degree of thrombocytopenia although the current practice of prompt IABP removal may offset this effect.
Journal of Interventional Cardiology – Wiley
Published: Aug 1, 2008
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.