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K. Sjauw, M. Remmelink, J. Baan, Kayan Lam, A. Engström, R. Schaaf, M. Vis, K. Koch, J. Straalen, J. Tijssen, B. Mol, R. Winter, J. Piek, J. Henriques (2008)
Left ventricular unloading in acute ST-segment elevation myocardial infarction patients is safe and feasible and provides acute and sustained left ventricular recovery.Journal of the American College of Cardiology, 51 10
B. Fuller, R. Dellinger (2012)
Lactate as a hemodynamic marker in the critically illCurrent Opinion in Critical Care, 18
D. Perera, R. Stables, M. Thomas, J. Booth, M. Pitt, D. Blackman, A. Belder, S. Redwood (2010)
Elective intra-aortic balloon counterpulsation during high-risk percutaneous coronary intervention: a randomized controlled trial.JAMA, 304 8
A. Zangrillo, G. Landoni, G. Biondi-Zoccai, M. Greco, T. Greco, G. Frati, N. Patroniti, M. Antonelli, A. Pesenti, F. Pappalardo (2013)
A meta-analysis of complications and mortality of extracorporeal membrane oxygenation.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 15 3
B. Kar, I. Gregoric, Sukhdeep Basra, G. Idelchik, P. Loyalka (2011)
The percutaneous ventricular assist device in severe refractory cardiogenic shock.Journal of the American College of Cardiology, 57 6
A. Lauten, A. Engström, C. Jung, K. Empen, P. Erne, S. Cook, S. Windecker, M. Bergmann, R. Klingenberg, T. Lüscher, M. Haude, D. Rulands, C. Butter, B. Ullman, L. Hellgren, M. Modena, G. Pedrazzini, J. Henriques, H. Figulla, M. Ferrari (2013)
Percutaneous Left-Ventricular Support With the Impella-2.5–Assist Device in Acute Cardiogenic Shock: Results of the Impella–EUROSHOCK-RegistryCirculation: Heart Failure, 6
S. Dixon, J. Henriques, L. Mauri, K. Sjauw, A. Civitello, B. Kar, P. Loyalka, F. Resnic, P. Teirstein, R. Makkar, I. Palacios, M. Collins, J. Moses, K. Benali, W. O’Neill (2009)
A prospective feasibility trial investigating the use of the Impella 2.5 system in patients undergoing high-risk percutaneous coronary intervention (The PROTECT I Trial): initial U.S. experience.JACC. Cardiovascular interventions, 2 2
William O'Neill, T. Schreiber, D. Wohns, C. Rihal, Srihari Naidu, ANDREW Civitello, Simon Dixon, JOSEPH Massaro, Brijeshwar Maini, E. Ohman (2013)
The Current Use of Impella 2.5 in Acute Myocardial Infarction Complicated by Cardiogenic Shock: Results from the USpella RegistryJournal of Interventional Cardiology, 27
F. Ferreira, D. Bota, A. Bross, C. Mélot, J. Vincent (2001)
Serial evaluation of the SOFA score to predict outcome in critically ill patients.JAMA, 286 14
O'Neill (2012)
A prospective, randomized clinical trial of hemodynamic support with Impella 2.5 versus intra-aortic balloon pump in patients undergoing high-risk percutaneous coronary intervention: The PROTECT II studyCirculation, 126
N. Parakh (2012)
Intraaortic balloon support for myocardial infarction with cardiogenic shockIndian heart journal, 64
Maini (2014)
Percutaneous cardiac assist devices compared with surgical hemodynamic support alternatives: Cost-Effectiveness in the Emergent SettingCatheter Cardiovasc Interv, 83
R. Cubeddu, R. Lago, Sofia Horvath, P. Vignola, W. O'neill, I. Palacios (2012)
Use of the Impella 2.5 system alone, after and in combination with an intra-aortic balloon pump in patients with cardiogenic shock: case description and review of the literature.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 7 12
H. Reynolds, J. Hochman (2008)
Cardiogenic Shock: Current Concepts and Improving OutcomesCirculation, 117
Zeymer (2004)
Predictors of in-hospital mortality in 1333 patients with acute myocardial infarction complicated by cardiogenic shock treated with primary percutaneous coronary intervention (PCI), Results of the primary PCI registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK)Eur Heart J, 25
Thiele (2012)
Intraaortic balloon support for myocardial infarction with cardiogenic shockN Engl J Med, 367
R. Cheng, R. Hachamovitch, M. Kittleson, J. Patel, F. Arabía, J. Moriguchi, F. Esmailian, B. Azarbal (2014)
Complications of extracorporeal membrane oxygenation for treatment of cardiogenic shock and cardiac arrest: a meta-analysis of 1,866 adult patients.The Annals of thoracic surgery, 97 2
M. Patel, R. Smalling, H. Thiele, H. Barnhart, Yi Zhou, P. Chandra, D. Chew, Marc Cohen, J. French, D. Perera, E. Ohman (2011)
Intra-aortic balloon counterpulsation and infarct size in patients with acute anterior myocardial infarction without shock: the CRISP AMI randomized trial.JAMA, 306 12
Hyungtae Kim, S. Lim, Joonhwa Hong, Y. Hong, Cheol-Joo Lee, Joonho Jung, Saehwan Yu (2012)
Efficacy of veno-arterial extracorporeal membrane oxygenation in acute myocardial infarction with cardiogenic shock.Resuscitation, 83 8
Omeed Saghafi (2012)
Intra-aortic Balloon Counterpulsation and Infarct Size in Patients with Acute Anterior Myocardial Infarction without Shock: The CRISP AMI Randomized TrialJournal of Emergency Medicine, 42
M. Seyfarth, D. Sibbing, I. Bauer, G. Fröhlich, Lorenz Bott-Flügel, R. Byrne, J. Dirschinger, A. Kastrati, A. Schömig (2008)
A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ventricular assist device versus intra-aortic balloon pumping for treatment of cardiogenic shock caused by myocardial infarction.Journal of the American College of Cardiology, 52 19
U. Zeymer, A. Vogt, R. Al (2004)
Predictors of in-hospital mortality in 1333 patients with acute myocardial infarction complicated by cardiogenic shock treated with primary percutaneous coronary intervention (PCI): Results of the primary PCI registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK)
K. Thygesen, J. Alpert, A. Jaffe, M. Simoons, B. Chaitman, H. White, K. Thygesen, H. Katus, F. Apple, B. Lindahl, D. Morrow, Bernard Chaitman, P. Clemmensen, P. Johanson, H. Hod, R. Underwood, Jeroen Bax, R. Bonow, F. Pinto, R. Gibbons, K. Fox, D. Atar, L. Newby, M. Galvani, C. Hamm, B. Uretsky, P. Steg, W. Wijns, J. Bassand, P. Menasche, J. Ravkilde, E. Ohman, E. Antman, L. Wallentin, P. Armstrong, J. Januzzi, M. Nieminen, M. Gheorghiade, G. Filippatos, R. Luepker, S. Fortmann, W. Rosamond, D. Levy, D. Wood, Sidney Smith, D. Hu, J. López-Sendón, R. Robertson, D. Weaver, M. Tendera, A. Bove, A. Parkhomenko, E. Vasilieva, S. Mendis (2013)
Third universal definition of myocardial infarctionNature Reviews Cardiology, 9
Brijeshwar Maini, L. Buyantseva, kate acquaviva, Aneel Maini, D. Scotti, D. Gregory (2013)
PERCUTANEOUS CARDIAC ASSIST DEVICES COMPARED WITH SURGICAL HEMODYNAMIC SUPPORT ALTERNATIVES: COST–EFFECTIVENESS IN THE EMERGENT SETTINGJournal of the American College of Cardiology, 61
J. Roos, S. Doshi, T. Konorza, I. Palacios, T. Schreiber, O. Borisenko, J. Henriques (2013)
The cost-effectiveness of a new percutaneous ventricular assist device for high-risk PCI patients: mid-stage evaluation from the European perspectiveJournal of Medical Economics, 16
A. Engström, K. Sjauw, J. Baan, M. Remmelink, B. Claessen, W. Kikkert, L. Hoebers, M. Vis, K. Koch, M. Meuwissen, J. Tijssen, R. Winter, J. Piek, J. Henriques (2011)
Long-term safety and sustained left ventricular recovery: long-term results of percutaneous left ventricular support with Impella LP2.5 in ST-elevation myocardial infarction.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 6 7
J. Zimmerman, D. Wagner, E. Draper, D. Lawrence (1981)
APACHE—acute physiology and chronic health evaluation: a physiologically based classification systemCritical Care Medicine, 9
H. Thiele, U. Zeymer, F. Neumann, Miroslaw Ferenc, H. Olbrich, J. Hausleiter, A. Waha, G. Richardt, M. Hennersdorf, K. Empen, G. Fuernau, S. Desch, I. Eitel, R. Hambrecht, B. Lauer, M. Böhm, H. Ebelt, S. Schneider, K. Werdan, G. Schuler (2013)
Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trialThe Lancet, 382
Objectives To investigate the outcome of patients with acute myocardial infarction (AMI) complicated by refractory cardiogenic shock (CS) who underwent mechanical circulatory support with Impella 2.5. Background AMI complicated by CS remains a highly fatal condition. A potent and minimally invasive left ventricular assist device might improve patient outcomes. Methods We analyzed the procedural characteristics and outcomes of 22 consecutive patients who underwent, between July 2008 and December 2012, a percutaneous coronary intervention and Impella 2.5 support for AMI complicated by CS refractory to first‐line therapy with inotropes and/or Intra‐aortic balloon pump. Results In this analysis, patients were relatively young with a mean age of 57.9 ± 11.6 year old and 59.1% were male. The majority of patients (77.3%) were admitted in CS and 40.9% sustained cardiac arrest prior to admission. Hemodynamics improved significantly upon initiation of support, end‐organ and tissue perfusion improved subsequently demonstrated by a significant decrease in lactate levels from 6.37 ± 5.3 mmol/L to 2.41 ± 2.1 mmo/L, (P = 0.008) after 2 days of support. Thirteen (59.1%) patients were successfully weaned‐off Impella 2.5 and 4 (18.2%) were transitioned to another device. We observed a functional recovery of the left ventricle when compared to baseline (43 ± 10% vs. 27 ± 9%, P < 0.0001). The survival rate at 6 months and 1 year was 59.1% and 54.5%, respectively. Conclusion Impella 2.5 was initiated as a last resort therapy to support very sick patients with refractory CS after failed conventional therapy. The use of the device yielded favorable short and mid‐term survival results with recovery being the most frequently observed outcome. (J Interven Cardiol 2015;28:41–50)
Journal of Interventional Cardiology – Wiley
Published: Feb 1, 2015
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