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ISSN 0905-6157 The role of the atopy patch test (APT) in diagnosis of food allergy in infants and children with atopic dermatitis Niggemann B. The role of the atopy patch test (APT) in diagnosis of food allergy in infants and children with atopic dermatitis. Pediatr Allergy Immunol 2001: 12(suppl 14): 37â40. # Munksgaard 2001. Bodo Niggemann Department of Pneumology and Immunology, ´ University Childrenâs Hospital Charite of Humboldt University, Berlin, Germany Key words: atopic dermatitis; allergy; atopy patch test; children; food allergy B. Niggemann, Department of Pediatric Pneumology and Immunology, Childrenâs ´ Hospital Charite, Humboldt University, Augustenburger Platz 1, D-13353 Berlin, Germany Introduction Pathomechanism Food allergy has been demonstrated to play an important role in the pathogenesis of atopic dermatitis (AD), affecting around one-third of children (1. . The most commonly offending foods ) are cowâs milk (CM), henâs egg (HE), wheat, and soy. While immediate type clinical reactions to food (e.g. urticaria, bronchial obstruction after 10â20 min) can be identiï¬ed quite easily, late phase reactions (e.g. worsening of eczema on the next day) still present diagnostic difï¬culties. Even double-blind, placebo-controlled oral food challenges (DBPCFC) â the gold standard of diagnosis in food allergy (2. â are not
Pediatric Allergy and Immunology – Wiley
Published: May 1, 2001
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