Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/wiley/the-quorum-quenching-lactonase-from-alicyclobacter-acidoterrestris-RignISdwuY
References (26)
-
M. Elias, Dan Tawfik (2011)
Divergence and Convergence in Enzyme Evolution: Parallel Evolution of Paraoxonases from Quorum-quenching Lactonases*The Journal of Biological Chemistry, 287
-
D. Xiang, P. Kolb, A. Fedorov, Monika Meier, L. Fedorov, T. Nguyen, R. Sterner, S. Almo, B. Shoichet, F. Raushel (2009)
Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily.Biochemistry, 48 10
-
M. Ben-David, J. Sussman, Christopher Maxwell, Klaudia Szeler, Shina Kamerlin, Dan Tawfik (2015)
Catalytic stimulation by restrained active-site floppiness--the case of high density lipoprotein-bound serum paraoxonase-1.Journal of molecular biology, 427 6 Pt B
-
A. Hawe, M. Sutter, W. Jiskoot (2008)
Extrinsic Fluorescent Dyes as Tools for Protein CharacterizationPharmaceutical Research, 25
-
L. Afriat, C. Roodveldt, G. Manco, Dan Tawfik (2006)
The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase.Biochemistry, 45 46
-
(2008)
Biochemistry, 47, 7706–7714 -
M. Elias, J. Dupuy, Luigia Merone, L. Mandrich, E. Porzio, S. Moniot, D. Rochu, C. Lecomte, M. Rossi, P. Masson, G. Manco, E. Chabrière (2008)
Structural basis for natural lactonase and promiscuous phosphotriesterase activities.Journal of molecular biology, 379 5
-
R. Hawwa, S. Larsen, K. Ratia, A. Mesecar (2009)
Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans.Journal of molecular biology, 393 1
-
B. Bassler (1999)
How bacteria talk to each other: regulation of gene expression by quorum sensing.Current opinion in microbiology, 2 6
-
Breah LaSarre, Michael Federle (2013)
Exploiting Quorum Sensing To Confuse Bacterial PathogensMicrobiology and Molecular Biology Reviews, 77
-
M. Ben-David, G. Wieczorek, M. Elias, I. Silman, J. Sussman, Dan Tawfik (2013)
Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme.Journal of molecular biology, 425 6
-
Dali Liu, P. Thomas, Jessica Momb, Q. Hoang, G. Petsko, D. Ringe, W. Fast (2007)
Structure and specificity of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens.Biochemistry, 46 42
-
Dali Liu, Jessica Momb, P. Thomas, A. Moulin, G. Petsko, W. Fast, D. Ringe (2008)
Mechanism of the Quorum-Quenching Lactonase (AiiA) from Bacillus thuringiensis. 1. Product-Bound Structures†‡Biochemistry, 47
-
O. Khersonsky, Dan Tawfik (2005)
Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase.Biochemistry, 44 16
-
Hagit Bar-Rogovsky, Adrian Hugenmatter, Dan Tawfik (2013)
The Evolutionary Origins of Detoxifying EnzymesThe Journal of Biological Chemistry, 288
-
P. Vecchio, M. Elias, Luigia Merone, G. Graziano, J. Dupuy, L. Mandrich, P. Carullo, B. Fournier, D. Rochu, M. Rossi, P. Masson, E. Chabrière, G. Manco (2009)
Structural determinants of the high thermal stability of SsoPox from the hyperthermophilic archaeon Sulfolobus solfataricusExtremophiles, 13
-
Melissa Miller, B. Bassler (2001)
Quorum sensing in bacteria.Annual review of microbiology, 55
-
A. Schaefer, E. Greenberg, Colin Oliver, Y. Oda, Jean Huang, Gili Bittan‐Banin, C. Peres, S. Schmidt, K. Juhaszova, J. Sufrin, C. Harwood (2008)
A new class of homoserine lactone quorum-sensing signalsNature, 454
-
Jessica Momb, Canhui Wang, Dali Liu, P. Thomas, G. Petsko, Hua Guo, D. Ringe, W. Fast (2008)
Mechanism of the Quorum-Quenching Lactonase (AiiA) from Bacillus thuringiensis. 2. Substrate Modeling and Active Site Mutations†Biochemistry, 47
-
(2014)
BMC Res -
H. Lade, Diby Paul, J. Kweon (2014)
N-Acyl Homoserine Lactone-Mediated Quorum Sensing with Special Reference to Use of Quorum Quenching Bacteria in Membrane Biofouling ControlBioMed Research International, 2014
-
A. Spinelli, A. Sant’Ana, Salatir Rodrigues-Junior, P. Massaguer (2009)
Influence of Different Filling, Cooling, and Storage Conditions on the Growth of Alicyclobacillus acidoterrestris CRA7152 in Orange JuiceApplied and Environmental Microbiology, 75
-
(1993)
PLoS One, 8, e75272 -
J. Hiblot, J. Bzdrenga, Charlotte Champion, E. Chabrière, M. Elias (2015)
Crystal structure of VmoLac, a tentative quorum quenching lactonase from the extremophilic crenarchaeon Vulcanisaeta moutnovskiaScientific Reports, 5
-
W. Kabsch (1993)
Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constantsJournal of Applied Crystallography, 26
-
Nimmy Augustine, Praveen Kumar, Sabu Thomas (2010)
Inhibition of Vibrio cholerae biofilm by AiiA enzyme produced from Bacillus spp.Archives of Microbiology, 192
- Publisher
- Wiley
- Copyright
- Copyright © 2017 Wiley Subscription Services
- ISSN
- 2053-230X
- eISSN
- 2053-230X
- DOI
- 10.1107/S2053230X17010640
- pmid
- 28777091
- Publisher site
- See Article on Publisher Site
Abstract
Lactonases comprise a class of enzymes that hydrolyze lactones, including acyl‐homoserine lactones (AHLs); the latter are used as chemical signaling molecules by numerous Gram‐negative bacteria. Lactonases have therefore been demonstrated to quench AHL‐based bacterial communication. In particular, lactonases are capable of inhibiting bacterial behaviors that depend on these chemicals, such as the formation of biofilms or the expression of virulence factors. A novel representative from the metallo‐β‐lactamase superfamily, named AaL, was isolated from the thermoacidophilic bacterium Alicyclobacter acidoterrestris. Kinetic characterization proves AaL to be a proficient lactonase, with catalytic efficiencies (kcat/Km) against AHLs in the region of 105 M−1 s−1. AaL exhibits a very broad substrate specificity. Its structure is expected to reveal the molecular determinants for its substrate binding and specificity, as well as to provide grounds for future protein‐engineering projects. Here, the expression, purification, characterization, crystallization and X‐ray diffraction data collection of AaL at 1.65 Å resolution are reported.
Journal
Acta Crystallographica Section F – Wiley
Published: Jan 1, 2017
Keywords: ; ; ; ;