Access the full text.
Sign up today, get DeepDyve free for 14 days.
R. Fisher (1946)
The fitting of gene frequencies to data on rhesus reactions.Annals of eugenics, 13 Pt 2
Finney Finney (1948b)
The estimation of gene frequencies from family records. II. Factors with dominanceHeredity, 2
Stevens Stevens (1938)
Estimation of blood‐group gene frequenciesAnn. Eugen., Lond., 8
I. Bianco, R. Ceppellini, E. Silvestroni, M. Siniscalco (1954)
DATA FOR THE STUDY OF LINKAGE IN MAN. MICROCYTHAEMIA and THE LEWIS‐SECRETOR CHARACTERSAnnals of Human Genetics, 19
(1954)
Shortencd maximum likelihood estimation of Rh gcno frequencies
Cotterman Cotterman (1947)
A weighting system for the evaluation of gene frequencies from family recordsContr. Lab. Vertebr. Biol. Univ. Mich.
W. Stevens (1938)
ESTIMATION OF BLOOD‐GROUP GENE FREQUENCIESAnnals of Human Genetics, 8
(1937)
Studies in practical mathematics
D. Finney (1948)
The estimation of gene frequencies from family recordsHeredity, 2
A. Aitken (1938)
XX.—Studies in Practical Mathematics. II. The Evaluation of the Latent Roots and Latent Vectors of a Matrix, 57
W. Boyd (1954)
Maximum likelihood method for estimation of gene frequencies from MNS data.American journal of human genetics, 6 1
(1951)
The Meurn rement of Linktrge in Hereddy, 2nd ed
R. Fisher (1940)
THE ESTIMATION OF THE PROPORTION OF RECESSIVES FROM TESTS CARRIED OUT ON A SAMPLE NOT WHOLLY UNRELATEDAnnals of Human Genetics, 10
Fisher Fisher (1940)
The estimation of the proportion of recessives from tests carried out on a sample not wholly unrelatedAnn. Eugen., Lond., 10
BY R. CEPPELLINI, lstituto Sieroterapico Milanese, Milano, Italy M. SINISCALCO, Istituto d i Genetica, Universitri, Napoli, Italy AND C. A. B. SMITH, Galton Laboratory, University College, London 1. The estimation of gene frequencies in a population is an important problem in human genetics and anthropology, especially where blood groups are concerned. Much work has already been done on this problem, notably by W. L. Stevens (1938), R. A. Fisher (1940, 1946), C. W. Cotterman (1947), D. J. Finney (1948a, b), W. C. Boyd (1954a, b ) , and others. Here we give a general procedure applicable (under very general conditions) both to samples of unrelated individuals and to families. This method is applied to data on blood groups collected from villages near the mouth of the River Po, in northern Italy, in the course of an investigation on microcythaemia (Bianco, Ceppellini, Silvestroni & Siniscalco, 1954). Experience shows that this new method of computation is reasonably rapid, except in the case of a rare, or fairly rare, recessive gene, or when such a gene is present in a series of alleles. It may also become laborious when there are complicated families and a system of several alleles; in this
Annals of Human Genetics – Wiley
Published: Nov 1, 1955
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.