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The Editor recommends this issue's articles to the reader

The Editor recommends this issue's articles to the reader Asthma symptoms and medication in the PIAMA birth cohort: Evidence for under‐ and/or overtreatment Daan Caudri [author] In this issue of Paediatric Allergy and Immunology, Caudri et al. ( 1 ) report that both under‐ and overtreatment of asthma symptoms may be common in children aged 2–8 years. In the Dutch Prevention and Incidence of Asthma and Mite Allergy (PIAMA) birth cohort, the authors compared annually reported respiratory symptoms with reported medication use. About one‐third of the children with severe asthma symptoms were not using inhaled corticosteroids. Of the 8‐year‐old children using inhaled corticosteroids for at least 2 years, 25% did not report any symptoms of wheezing or shortness of breath during those 2 years. The authors speculate that incorrect treatment may frequently occur because of the difficulties in diagnosing asthma in young children. According to the authors, this study underlines the importance of regular follow‐up by general practitioners or pediatricians, especially to prevent overtreatment of transient symptoms. The association of maternal prenatal IgE and eczema in offspring is restricted to non‐atopic mothers William Hicks [author] The onset of eczema during early childhood is often the first indication that a child will develop subsequent allergic disease. In this issue of Pediatric Allergy and Immunology, Hicks et al. ( 2 ) report that higher maternal IgE levels during the last trimester of pregnancy are associated with higher risk of eczema by the age of 2 years in their offspring. Data from 458 children participating in a Detroit area population‐based birth cohort study indicated that the relationship between eczema and maternal IgE was evident only among mothers that were not sensitized to common allergens and that the relationship was independent of the presence or absence of a maternal history of clinical allergy or asthma. This research supports the concept that during pregnancy, maternal IgE or concurrent factors that promote maternal IgE production may be impacting their developing child’s risk of eczema and also perhaps the child’s subsequent allergic disease risk. Although a causal mechanism could not be identified, the authors suggest that since the observed relationship was present among non‐atopic mothers that maternal IgE’s association with eczema in their offspring was unlikely to be secondary to its role in mediating allergen‐specific sensitization. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Allergy and Immunology Wiley

The Editor recommends this issue's articles to the reader

Pediatric Allergy and Immunology , Volume 22 (7) – Nov 1, 2011
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References (2)

Publisher
Wiley
Copyright
Copyright © 2011 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0905-6157
eISSN
1399-3038
DOI
10.1111/j.1399-3038.2011.01216.x
Publisher site
See Article on Publisher Site

Abstract

Asthma symptoms and medication in the PIAMA birth cohort: Evidence for under‐ and/or overtreatment Daan Caudri [author] In this issue of Paediatric Allergy and Immunology, Caudri et al. ( 1 ) report that both under‐ and overtreatment of asthma symptoms may be common in children aged 2–8 years. In the Dutch Prevention and Incidence of Asthma and Mite Allergy (PIAMA) birth cohort, the authors compared annually reported respiratory symptoms with reported medication use. About one‐third of the children with severe asthma symptoms were not using inhaled corticosteroids. Of the 8‐year‐old children using inhaled corticosteroids for at least 2 years, 25% did not report any symptoms of wheezing or shortness of breath during those 2 years. The authors speculate that incorrect treatment may frequently occur because of the difficulties in diagnosing asthma in young children. According to the authors, this study underlines the importance of regular follow‐up by general practitioners or pediatricians, especially to prevent overtreatment of transient symptoms. The association of maternal prenatal IgE and eczema in offspring is restricted to non‐atopic mothers William Hicks [author] The onset of eczema during early childhood is often the first indication that a child will develop subsequent allergic disease. In this issue of Pediatric Allergy and Immunology, Hicks et al. ( 2 ) report that higher maternal IgE levels during the last trimester of pregnancy are associated with higher risk of eczema by the age of 2 years in their offspring. Data from 458 children participating in a Detroit area population‐based birth cohort study indicated that the relationship between eczema and maternal IgE was evident only among mothers that were not sensitized to common allergens and that the relationship was independent of the presence or absence of a maternal history of clinical allergy or asthma. This research supports the concept that during pregnancy, maternal IgE or concurrent factors that promote maternal IgE production may be impacting their developing child’s risk of eczema and also perhaps the child’s subsequent allergic disease risk. Although a causal mechanism could not be identified, the authors suggest that since the observed relationship was present among non‐atopic mothers that maternal IgE’s association with eczema in their offspring was unlikely to be secondary to its role in mediating allergen‐specific sensitization.

Journal

Pediatric Allergy and Immunology – Wiley

Published: Nov 1, 2011

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