Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/wiley/the-crystal-structure-of-pd1-a-haemophilus-surface-fibril-domain-jXlJ0pwPlB
References (35)
-
(2014)
J. Struct. Biol -
Birendra Singh, T. Jubair, M. Mörgelin, A. Sundin, S. Linse, U. Nilsson, K. Riesbeck (2015)
Haemophilus influenzae surface fibril (Hsf) is a unique twisted hairpin-like trimeric autotransporter.International journal of medical microbiology : IJMM, 305 1
-
(2006)
J. Immunol -
(2009)
Pediatr. Infect. Dis. J -
(2008)
PLoS Med -
A. Mccoy, R. Grosse-Kunstleve, P. Adams, M. Winn, L. Storoni, R. Read (2007)
Phaser crystallographic softwareJournal of Applied Crystallography, 40
-
M. Hartmann, I. Grin, S. Dunin-Horkawicz, S. Deiss, D. Linke, A. Lupas, B. Alvarez (2012)
Complete fiber structures of complex trimeric autotransporter adhesins conserved in enterobacteriaProceedings of the National Academy of Sciences, 109
-
S. Barenkamp, J. Geme (1996)
Identification of a second family of high‐molecular‐weight adhesion proteins expressed by non‐typable Haemophilus influenzaeMolecular Microbiology, 19
-
(2004)
EMBO J -
H. Yeo, Shane Cotter, S. Laarmann, T. Juehne, J. Geme, G. Waksman (2004)
Structural basis for host recognition by the Haemophilus influenzae Hia autotransporterThe EMBO Journal, 23
-
(1996)
Mol. Microbiol -
(2014)
Infect. Immun -
B. Alvarez, M. Hartmann, R. Albrecht, A. Lupas, K. Zeth, D. Linke (2007)
A new expression system for protein crystallization using trimeric coiled-coil adaptors.Protein engineering, design & selection : PEDS, 21 1
-
U. Lehr, M. Schütz, Philipp Oberhettinger, F. Ruiz-Perez, James Donald, T. Palmer, D. Linke, I. Henderson, I. Autenrieth (2010)
C‐terminal amino acid residues of the trimeric autotransporter adhesin YadA of Yersinia enterocolitica are decisive for its recognition and assembly by BamAMolecular Microbiology, 78
-
S. Deiss, B. Alvarez, Kerstin Bär, Carolin Ewers, M. Coles, R. Albrecht, M. Hartmann (2014)
Your personalized protein structure: Andrei N. Lupas fused to GCN4 adaptors.Journal of structural biology, 186 3
-
R. Virkola, M. Brummer, H. Rauvala, L. Alphen, Timo Korhonen (2000)
Interaction of Fimbriae of Haemophilus influenzae Type B with Heparin-Binding Extracellular Matrix ProteinsInfection and Immunity, 68
-
G. Meng, J. Geme, G. Waksman (2008)
Repetitive Architecture of the Haemophilus influenzae Hia Trimeric AutotransporterJournal of Molecular Biology, 384
-
S. Laarmann, D. Cutter, T. Juehne, S. Barenkamp, J. Geme (2002)
The Haemophilus influenzae Hia autotransporter harbours two adhesive pockets that reside in the passenger domain and recognize the same host cell receptorMolecular Microbiology, 46
-
K. Koiwai, M. Hartmann, D. Linke, A. Lupas, K. Hori (2015)
Structural Basis for Toughness and Flexibility in the C-terminal Passenger Domain of an Acinetobacter Trimeric Autotransporter Adhesin*The Journal of Biological Chemistry, 291
-
(2010)
Acta Cryst. D66 -
(2008)
Protein Eng. Des. Sel -
(2004)
research papers Acta Crystallographica Section D Biological -
T. Murphy, H. Faden, L. Bakaletz, J. Kyd, A. Forsgren, J. Campos, M. Virji, S. Pelton (2009)
Nontypeable Haemophilus influenzae as a Pathogen in ChildrenThe Pediatric Infectious Disease Journal, 28
-
Shane Cotter, H. Yeo, T. Juehne, J. Geme (2005)
Architecture and Adhesive Activity of the Haemophilus influenzae Hsf AdhesinJournal of Bacteriology, 187
-
B. Alvarez, M. Gruber, A. Ursinus, S. Dunin-Horkawicz, A. Lupas, K. Zeth (2010)
A transition from strong right-handed to canonical left-handed supercoiling in a conserved coiled-coil segment of trimeric autotransporter adhesins.Journal of structural biology, 170 2
-
T. Hallström, E. Trajkovska, A. Forsgren, K. Riesbeck (2006)
Haemophilus influenzae Surface Fibrils Contribute to Serum Resistance by Interacting with Vitronectin1The Journal of Immunology, 177
-
H. Nummelin, M. Merckel, J. Leo, H. Lankinen, M. Skurnik, A. Goldman (2004)
The Yersinia adhesin YadA collagen‐binding domain structure is a novel left‐handed parallel β‐rollThe EMBO Journal, 23
-
M. Danovaro-Holliday, S. Garcia, C. Quadros, G. Tambini, J. Andrus (2008)
Progress in Vaccination against Haemophilus influenzae type b in the AmericasPLoS Medicine, 5
-
(2016)
J. Biol. Chem -
P. Evans, G. Murshudov (2013)
How good are my data and what is the resolution?Acta Crystallographica Section D: Biological Crystallography, 69
-
Paweł Szczęsny, D. Linke, A. Ursinus, Kerstin Bär, H. Schwarz, Tanja Riess, V. Kempf, A. Lupas, Jörg Martin, K. Zeth (2008)
Structure of the Head of the Bartonella Adhesin BadAPLoS Pathogens, 4
-
(2007)
J. Appl. Cryst -
(2012)
Proc. Natl Acad. Sci. USA -
Birendra Singh, Yu-Ching Su, Tamim Al-Jubair, Oindrilla Mukherjee, T. Hallström, M. Mörgelin, A. Blom, K. Riesbeck (2014)
A Fine-Tuned Interaction between Trimeric Autotransporter Haemophilus Surface Fibrils and Vitronectin Leads to Serum Resistance and Adherence to Respiratory Epithelial CellsInfection and Immunity, 82
-
(2008)
PLoS Pathog
- Publisher
- Wiley
- Copyright
- Copyright © 2017 Wiley Subscription Services
- ISSN
- 2053-230X
- eISSN
- 2053-230X
- DOI
- 10.1107/S2053230X17001406
- pmid
- 28177321
- Publisher site
- See Article on Publisher Site
Abstract
The Haemophilus surface fibril (Hsf) is an unusually large trimeric autotransporter adhesin (TAA) expressed by the most virulent strains of H. influenzae. Hsf is known to mediate adhesion between pathogen and host, allowing the establishment of potentially deadly diseases such as epiglottitis, meningitis and pneumonia. While recent research has suggested that this TAA might adopt a novel `hairpin‐like' architecture, the characterization of Hsf has been limited to in silico modelling and electron micrographs, with no high‐resolution structural data available. Here, the crystal structure of Hsf putative domain 1 (PD1) is reported at 3.3 Å resolution. The structure corrects the previous domain annotation by revealing the presence of an unexpected N‐terminal TrpRing domain. PD1 represents the first Hsf domain to be solved, and thus paves the way for further research on the `hairpin‐like' hypothesis.
Journal
Acta Crystallographica Section F – Wiley
Published: Jan 1, 2017
Keywords: ; ; ; ; ;