Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

The content of hippocampal “replay”

The content of hippocampal “replay” One of the most striking features of the hippocampal network is its ability to self‐generate neuronal sequences representing temporally compressed, spatially coherent paths. These brief events, often termed “replay” in the scientific literature, are largely confined to non‐exploratory states such as sleep or quiet rest. Early studies examining the content of replay noted a strong correlation between the encoded spatial information and the animal's prior behavior; thus, replay was initially hypothesized to play a role in memory formation and/or systems‐level consolidation via “off‐line” reactivation of previous experiences. However, recent findings indicate that replay may also serve as a memory retrieval mechanism to guide future behavior or may be an incidental reflection of pre‐existing network assemblies. Here, I will review what is known regarding the content of replay events and their correlation with past and future actions, and I will discuss how this knowledge might inform or constrain models which seek to explain the circuit‐level mechanisms underlying these events and their role in mnemonic processes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Hippocampus Wiley

The content of hippocampal “replay”

Pfeiffer, Brad E.
Hippocampus , Volume 30 (1) – Jan 1, 2020
Download PDF
13 pages

Loading next page...
 
/lp/wiley/the-content-of-hippocampal-replay-kAbtT04T0U

References (121)

Publisher
Wiley
Copyright
© 2020 Wiley Periodicals, Inc.
ISSN
1050-9631
eISSN
1098-1063
DOI
10.1002/hipo.22824
Publisher site
See Article on Publisher Site

Abstract

One of the most striking features of the hippocampal network is its ability to self‐generate neuronal sequences representing temporally compressed, spatially coherent paths. These brief events, often termed “replay” in the scientific literature, are largely confined to non‐exploratory states such as sleep or quiet rest. Early studies examining the content of replay noted a strong correlation between the encoded spatial information and the animal's prior behavior; thus, replay was initially hypothesized to play a role in memory formation and/or systems‐level consolidation via “off‐line” reactivation of previous experiences. However, recent findings indicate that replay may also serve as a memory retrieval mechanism to guide future behavior or may be an incidental reflection of pre‐existing network assemblies. Here, I will review what is known regarding the content of replay events and their correlation with past and future actions, and I will discuss how this knowledge might inform or constrain models which seek to explain the circuit‐level mechanisms underlying these events and their role in mnemonic processes.

Journal

Hippocampus – Wiley

Published: Jan 1, 2020

Keywords: ; ; ; ;

There are no references for this article.