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The chromosomes in two patients with Klinefelter syndrome

The chromosomes in two patients with Klinefelter syndrome Summary Serially grown cultures of skin cells from two Klinefelter patients were established for the purpose of obtaining material for chromosome analysis. In both cases the prevailing chromosome number was 47, probably representing the normal autosomes and XX Y. In both cases, chromosome numbers above 47 were seen. This deviation from the modal number was more pronounced in one of the two cases, in which some 30 % of the cells had forty‐eight or forty‐nine chromosomes. The nature of the extra chromosomes in these cells is discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

The chromosomes in two patients with Klinefelter syndrome

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References (26)

Publisher
Wiley
Copyright
Copyright © 1959 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1959.tb01718.x
Publisher site
See Article on Publisher Site

Abstract

Summary Serially grown cultures of skin cells from two Klinefelter patients were established for the purpose of obtaining material for chromosome analysis. In both cases the prevailing chromosome number was 47, probably representing the normal autosomes and XX Y. In both cases, chromosome numbers above 47 were seen. This deviation from the modal number was more pronounced in one of the two cases, in which some 30 % of the cells had forty‐eight or forty‐nine chromosomes. The nature of the extra chromosomes in these cells is discussed.

Journal

Annals of Human GeneticsWiley

Published: Sep 1, 1959

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