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Synthesis of porphyrin nitrogen mustards with potential anti‐tumor activities in chemotherapy and photodynamic therapy

Synthesis of porphyrin nitrogen mustards with potential anti‐tumor activities in chemotherapy and... 2,7,12,18‐Tetramethyl‐13,17‐di[3′‐N, N‐di(2″‐chloroethyl)aminopropyl]porphin and its 3,8‐di(1′‐alkyloxyethyl)‐analogous or porphyrin‐nitrogen mustards were synthesized for the first time. Their structures were determined by spectroscopies and elemental analyses. Most of the compounds possess both the chemotherapeutic and photodynamic effects on tumor and deserve further investigation. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chinese Journal of Chemistry Wiley

Synthesis of porphyrin nitrogen mustards with potential anti‐tumor activities in chemotherapy and photodynamic therapy

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References (5)

Publisher
Wiley
Copyright
Copyright © 1998 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1001-604X
eISSN
1614-7065
DOI
10.1002/cjoc.19980160610
Publisher site
See Article on Publisher Site

Abstract

2,7,12,18‐Tetramethyl‐13,17‐di[3′‐N, N‐di(2″‐chloroethyl)aminopropyl]porphin and its 3,8‐di(1′‐alkyloxyethyl)‐analogous or porphyrin‐nitrogen mustards were synthesized for the first time. Their structures were determined by spectroscopies and elemental analyses. Most of the compounds possess both the chemotherapeutic and photodynamic effects on tumor and deserve further investigation.

Journal

Chinese Journal of Chemistry – Wiley

Published: Nov 1, 1998

Keywords: ; ; ; ;

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