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Synthesis of Phosphinopeptides and Phosphinodepsipeptides

Synthesis of Phosphinopeptides and Phosphinodepsipeptides Both phosphinopeptides and phosphinodepsipeptides are important phosphorus analogues of naturally occurring peptides. They have been widely applied as biological active peptides, such as enzyme inhibitors, haptens for production of catalytic antibodies, and antibiotics. Synthetic methods of phosphinopeptides and phosphinodepsipeptides are reviewed and classified on the basis of the structural characteristics of aminoalkylphosphinic acids. This review focuses on the synthetic methods to phosphinopeptides and phosphinodepsipeptides, including α‐, β‐, and γ‐phosphinopeptides and α‐phosphinodepsipeptides. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Asian Journal of Organic Chemistry Wiley

Synthesis of Phosphinopeptides and Phosphinodepsipeptides

Asian Journal of Organic Chemistry , Volume 10 (2) – Feb 1, 2021

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References (1)

Publisher
Wiley
Copyright
© 2021 Wiley‐VCH GmbH
ISSN
2193-5807
eISSN
2193-5815
DOI
10.1002/ajoc.202000600
Publisher site
See Article on Publisher Site

Abstract

Both phosphinopeptides and phosphinodepsipeptides are important phosphorus analogues of naturally occurring peptides. They have been widely applied as biological active peptides, such as enzyme inhibitors, haptens for production of catalytic antibodies, and antibiotics. Synthetic methods of phosphinopeptides and phosphinodepsipeptides are reviewed and classified on the basis of the structural characteristics of aminoalkylphosphinic acids. This review focuses on the synthetic methods to phosphinopeptides and phosphinodepsipeptides, including α‐, β‐, and γ‐phosphinopeptides and α‐phosphinodepsipeptides.

Journal

Asian Journal of Organic ChemistryWiley

Published: Feb 1, 2021

Keywords: ; ; ; ;

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