Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Masoud, O. El-Hamid, Z. Zaki (1994)
2-thiouracil-based cobalt(II), nickel(II) and copper(II) complexesTransition Metal Chemistry, 19
R. Cramer, D. Patterson, J. Bunce (1988)
Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins.Journal of the American Chemical Society, 110 18
K. Yamanari, Makiko Kida, A. Fuyuhiro, M. Kita, S. Kaizaki (2002)
Cobalt(III) promoted ligand fusion reactions of thiobarbituric acid and 4,6-diamino-2-thiouracil (or 4-amino-2-thiouracil)Inorganica Chimica Acta, 332
N. Al-Masoudi, W. Pfleiderer, W. Al-Masoudi (1993)
Synthesis of Some Novel Acyclolumazine N-1 NucleosidesNucleosides, Nucleotides & Nucleic Acids, 12
W. Pfleiderer (1992)
Pteridines. Properties, reactivities and biological significanceJournal of Heterocyclic Chemistry, 29
H. Bömmel, A. Reif, L. Fröhlich, A. Frey, H. Hofmann, D. Marecak, V. Groehn, P. Kotsonis, M. La, S. Köster, M. Meinecke, Manfred Bernhardt, Monika Weeger, S. Ghisla, G. Prestwich, W. Pfleiderer, H. Schmidt (1998)
Anti-pterins as Tools to Characterize the Function of Tetrahydrobiopterin in NO Synthase*The Journal of Biological Chemistry, 273
P. Kotsonis, L. Fröhlich, C. Raman, Huiying Li, M. Berg, R. Gerwig, V. Groehn, Yong-Jin Kang, N. Al-Masoudi, Shahriyar Taghavi-Moghadam, Detlev Mohr, U. Münch, Joachim Schnabel, P. Martásek, B. Masters, H. Strobel, T. Poulos, H. Matter, W. Pfleiderer, H. Schmidt (2001)
Structural Basis for Pterin Antagonism in Nitric-oxide SynthaseThe Journal of Biological Chemistry, 276
W. Kaim, B. Schwederski, O. Heilmann, F. Hornung (1999)
Coordination compounds of pteridine, alloxazine and flavin ligands: structures and propertiesCoordination Chemistry Reviews, 182
V. Krishnamurthy, K. Rao, P. Rao, H. Praphulla (1967)
Some potential antiviral agents.British journal of pharmacology and chemotherapy, 31 1
L. Fröhlich, P. Kotsonis, H. Traub, Shahriyar Taghavi-Moghadam, N. Al-Masoudi, H. Hofmann, Hartmut Strobel, Hans Matter, Wolfgang Pfleiderer, Harald Schmidt (1999)
Inhibition of neuronal nitric oxide synthase by 4-amino pteridine derivatives: structure-activity relationship of antagonists of (6R)-5,6,7,8-tetrahydrobiopterin cofactor.Journal of medicinal chemistry, 42 20
N. Al-Masoudi, W. Pfleiderer (1990)
Nucleosides, XLVII. Syntheses, Reactions and Properties of 6- and 7-p-Bromophenyllumazine N-1-Nucleosides, 2
N. Al-Masoudi, W. Pfleiderer (1989)
Nucleosides, XLVI1 Syntheses and Reactions of 6- and 7-p-Chlorophenyllumazine NucleosidesNucleosides, Nucleotides & Nucleic Acids, 8
P. Khullar, U. Agarwala (1974)
2-Mercaptopyrimidin-4-ol (2-thiouracil) complexes of copper(II), nickel(II), cobalt(II) and iron(III)Australian Journal of Chemistry, 27
Francisco Hueso-Uren˜a, Sonia Jime´nez-Pulido, M. Moreno-Carretero, Miguel Quiro´s-Oloza´bal, Juan Salas-Peregri´n (1997)
A new three-dimensional, hydrogen-bonded metal-pteridine complex: synthesis, characterization and crystal structure of diaqua bis(1,3-dimethylpteridine-2,4(1H,3H)-dione-O4,N5) copper(II) nitrate dihydratePolyhedron, 16
O. Stanger, M. Weger (2003)
Interactions of Homocysteine, Nitric Oxide, Folate and Radicals in the Progressively Damaged Endothelium, 41
M. Pantke, A. Reif, J. Valtschanoff, Z. Shutenko, A. Frey, R. Weinberg, W. Pfleiderer, H. Schmidt (2001)
Pterin interactions with distinct reductase activities of NO synthase.The Biochemical journal, 356 Pt 1
N. Al-Masoudi, W. Pfleiderer (1993)
Nucleosides LIII Syntheses and Reactions of 6,7-Dipyridyllumazine and 2' -Deoxylumazine N-1 Nucleosides, 4
U. Singh, Sudha Singh, Sukhmahendra Singh (1998)
Synthesis, Characterization and Antitumour Activity of Metal Complexes of 5-Carboxy-2-ThiouracilMetal-Based Drugs, 5
M. Romero, M. Sánchez, M. Quirós, F. Sánchez, J. Salas, M. Moreno, R. Faure (1993)
Transition metal complexes of 6-amino 2-thiouracil; crystal structure of bis(6-amino-2-thiouracilato)aquazinc(II) dihydrateCanadian Journal of Chemistry, 71
Hiroaki Mitsuya, K. Weinhold, Furman Pa, Stern Mh, S. Lehrman, R. Gallo, D. Bolognesi, D. Barry, S. Broder (1985)
3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.Proceedings of the National Academy of Sciences of the United States of America, 82 20
H. Schneider, W. Pfleiderer (1974)
Pteridine, LXIV: Synthese und Eigenschaften von ThiolumazinenChemische Berichte, 107
Sonia Jiménez‐Pulido, Fátima Linares-Ordóñez, M. Moreno-Carretero (2009)
Novel coordination behavior of a pteridine-benzoylhydrazone ligand (BZLMH): Theoretical calculations, XRD structures and luminescence studiesPolyhedron, 28
F. Hueso-Ureña, Sonia Jiménez‐Pulido, M. Moreno-Carretero, M. Quirós-Olozábal, J. Salas-peregrin (1998)
Synthesis and structural studies on metal nitrate complexes with 1,3-dimethyllumazine and 1,3,6,7-tetramethyllumazine: crystal structure of two new cobalt(II) and copper(II) three-dimensionally hydrogen-bonded complexes and a cadmium(II) complex with unusual geometryInorganica Chimica Acta, 277
E. Raper (1985)
Complexes of heterocyclic thione donorsCoordination Chemistry Reviews, 61
F. Hueso-Ureña, Sonia Jiménez‐Pulido, M. Moreno-Carretero, M. Quirós-Olozábal, J. Salas-peregrin (1998)
Synthesis and structural studies on three-dimensionally hydrogen-bonded metal perchlorate complexes with 1,3-dimethyllumazine and 1,3,6,7-tetramethyllumazine. Crystal structure of diaqua-bis(1,3,6,7-tetramethyl-pteridine2,4(1H,3H)-dione-O4,N5) copper(II) perchlorate dihydrateInorganica Chimica Acta, 268
K. Hargrave, J. Proudfoot, K. Grozinger, Ernest Cullen, Suresh Kapadia, U. Patel, Victor Fuchs, S. Mauldin, J. Vitous, M. Behnke, J. Klunder, Kollol Pal, J. Skiles, Daniel McNeil, Janice Rose, Grace Chow, M. Skoog, Joe Wu, Günther Schmidt, Wolfhard Engel, Wolfgang Eberlein, T. Saboe, Scot Campbell, Alan Rosenthal, Julian Adams (1991)
Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 1. Tricyclic pyridobenzo- and dipyridodiazepinones.Journal of medicinal chemistry, 34 7
C. Suckling, C. Gibson, Judith Huggan, R. Morthala, Brenda Clarke, S. Kununthur, R. Wadsworth, S. Daff, D. Papale (2008)
6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases.Bioorganic & medicinal chemistry letters, 18 5
H. Ohshiro, K. Mitsui, N. Ando, Y. Ohsawa, W. Koinuma, H. Takahashi, S. Kondo, T. Nabeshima, Y. Yano (2001)
Oxidation-active flavin models: oxidation of alpha-hydroxy acids by benzo-dipteridine bearing metal-binding site in the presence of divalent metal ion and base in organic solvents.Journal of the American Chemical Society, 123 11
Esther Acuña-Cueva, R. Faure, Nuria Illán‐Cabeza, Sonia Jiménez‐Pulido, M. Moreno-Carretero, M. Quirós-Olozábal (2003)
Synthesis and characterization of several lumazine derivative complexes of Co(II), Ni(II), Cu(II), Cd(II), Pd(II) and Pt(II). X-ray structures of a mononuclear copper complex and a dinuclear cadmium complexInorganica Chimica Acta, 351
Ian Southon, W. Pfleiderer (1978)
Nucleoside, XXVIII. Synthese und Eigenschaften von 2‐Thiolumazin‐nucleosidenChemische Berichte, 111
A series of new Cu(II), Pt(II), VO(II), Fe(II), and Co(II) complexes (1‐‐5) with 3‐methyl‐6,7‐diphenyllumazine are described. Similarly, complexes from 2‐thiouracil with Cu(II) (6,7) and Pt(II) (8) have been prepared and characterized by spectroscopic methods. All the complexes were assayed for their anti‐HIV‐1 and HIV‐2 activity by examination of their inhibition of HIV‐induced cytopathogenicity in MT‐4 cells. Compound 3 was found to be the most active inhibitor against HIV‐2 in cell culture (EC50 = >18.9 μ g/mL, selectivity index (SI) = 3), which provided a good lead for further optimization. Compounds 6 and 7 exhibited some activity (EC50 = >7.12 μ g/mL and >2.23 μ g/mL) against HIV‐1 and HIV‐2, but no selectivity was observed (SI <1). © 2010 Wiley Periodicals, Inc. Heteroatom Chem 22:44–50, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.20654
Heteroatom Chemistry – Wiley
Published: Jan 1, 2011
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.