Access the full text.
Sign up today, get DeepDyve free for 14 days.
(2019)
Biomaterials 2021 , 269 , 120608;
(2021)
Reviews 2021 ,
(2021)
2022 , 427 , 130979; b) G.
(2021)
Materials Horizons
(2014)
Belowich, J.
(2019)
2021 , 121 , 1716-1745; b) P. Chakma, D. Konkolewicz
(2020)
ACS Appl
Hydrogels constructed from natural sources have received increased attention recently, including applications in biomedical fields. They are protein or polysaccharide cross‐linked scaffolds that display water retention and are able to recognize host cargos. Their excellent biocompatibility does not always combine with high mechanical strength (up to 136 kPa) and thermostability, making them less useful in biomedical applications. This paper reports biocompatible gelatin hydrogels, double cross‐linked via imine and Diels‐Alder (DA) dynamic covalent frameworks. They showed integrated advantages of adjustable and durable mechanical strength, good thermal stability, biocompatibility for promoting cell growth and reasonable degradable rate. These hydrogels possess remarkable self‐healing property, acid/alkali resistance at 65 °C and good integrity in organic solvents at 130 °C, holding great potential for biomedical applications in the areas such as cartilage regeneration, articular reconstruction or soft robotics.
ChemPlusChem – Wiley
Published: Nov 1, 2021
Keywords: Diels-Alder (DA) reaction; dynamic covalent chemistry; gelatin; hydrogels; imine
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.