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- Publisher
- Wiley
- Copyright
- © 2017 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim
- ISSN
- 2193-5807
- eISSN
- 2193-5815
- DOI
- 10.1002/ajoc.201700032
- Publisher site
- See Article on Publisher Site
Abstract
A stereoselective synthesis of entecavir, an anti‐hepatitis B (HBV) drug, was accomplished by a regioselective isopropylidene cleavage, stereoselective Sharpless epoxidation, and TiIII‐mediated regio‐ and stereoselective epoxide cleavage as key steps.
Journal
Asian Journal of Organic Chemistry – Wiley
Published: Sep 1, 2017
Keywords: ; ; ; ;