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Spotlights on our sister journals: ChemPlusChem 3/2016

Spotlights on our sister journals: ChemPlusChem 3/2016 On these pages, we feature aselection computer,click on any of the items to of the excellent work that has recently read the full article. Otherwise please been published in our sister journals. see the DOIs for easy online access If you are reading these pages on a through Wiley Online Library. Hydrogen Bonding Z. Wang, B. S. Gelfand, T. Baumgartner* Dithienophosphole-Based Phosphinamides with Intriguing Self-Assembly Behavior New HOPe:Dithienophosphole-basedphosphinamides (see struc- ture) display rotationally flexible hydrogen bonding that contrasts with that of their carboxamide cousins. Besides the novel hydrogen- bondingmotif, thesecompounds also demonstrated unique photo- physicaland amphiphilic properties as aresult of hydrogen-bond- directedself-assembly. Angew.Chem. Int. Ed. DOI: 10.1002/anie.201511171 Peptides A. Hayata,H.Itoh, S. Matsutaka, M. Inoue* Dual Chemical Modification of aPolytheonamide Mimic:Rational Design and SynthesisofIon-Channel-Forming 48-merPeptides with Potent Cytotoxicity Simpler but potent:Total synthesisand multiple functional analyses of seven new structurally simplified analogues of polytheonamide B, an ion-channel-forming 48-merpeptide, are reported. Structure–ac- tivity studies clarified that the bioactivity of the analogues can be rationally controlled by changing their hydrophobicity at residues 1 and 44 (see figure). The most hydrophobic analogueexhibited the Chem. Eur.J. highest cytotoxicity,whichisalmost as potent as that of polytheo- DOI: 10.1002/chem.201504632 namide B. Graphene A. Samal,D.P.Das,*K.K.Nanda, B. K. Mishra, J. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png ChemPlusChem Wiley

Spotlights on our sister journals: ChemPlusChem 3/2016

ChemPlusChem , Volume 81 (3) – Mar 1, 2016
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Publisher
Wiley
Copyright
© 2016 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
ISSN
2192-6506
eISSN
2192-6506
DOI
10.1002/cplu.201680313
Publisher site
See Article on Publisher Site

Abstract

On these pages, we feature aselection computer,click on any of the items to of the excellent work that has recently read the full article. Otherwise please been published in our sister journals. see the DOIs for easy online access If you are reading these pages on a through Wiley Online Library. Hydrogen Bonding Z. Wang, B. S. Gelfand, T. Baumgartner* Dithienophosphole-Based Phosphinamides with Intriguing Self-Assembly Behavior New HOPe:Dithienophosphole-basedphosphinamides (see struc- ture) display rotationally flexible hydrogen bonding that contrasts with that of their carboxamide cousins. Besides the novel hydrogen- bondingmotif, thesecompounds also demonstrated unique photo- physicaland amphiphilic properties as aresult of hydrogen-bond- directedself-assembly. Angew.Chem. Int. Ed. DOI: 10.1002/anie.201511171 Peptides A. Hayata,H.Itoh, S. Matsutaka, M. Inoue* Dual Chemical Modification of aPolytheonamide Mimic:Rational Design and SynthesisofIon-Channel-Forming 48-merPeptides with Potent Cytotoxicity Simpler but potent:Total synthesisand multiple functional analyses of seven new structurally simplified analogues of polytheonamide B, an ion-channel-forming 48-merpeptide, are reported. Structure–ac- tivity studies clarified that the bioactivity of the analogues can be rationally controlled by changing their hydrophobicity at residues 1 and 44 (see figure). The most hydrophobic analogueexhibited the Chem. Eur.J. highest cytotoxicity,whichisalmost as potent as that of polytheo- DOI: 10.1002/chem.201504632 namide B. Graphene A. Samal,D.P.Das,*K.K.Nanda, B. K. Mishra, J.

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ChemPlusChem – Wiley

Published: Mar 1, 2016

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