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Spanish and African contribution to the genetic pool of the Canary islanders: data from GM and KM haplotypes and RFLPs in the immunoglobulin IGHG loci

Spanish and African contribution to the genetic pool of the Canary islanders: data from GM and KM... Data on the GM and KM haplotypes and RFLPs in the immunoglobulin IGHG loci are reported intending to evaluate the genetic contribution of the different populations (Europeans and Africans) who settled Tenerife Island. The GM and KM allotypic systems reveal an estimated European genetic admixture of 88%. The only possible African contribution is the presence of the GM*1,17;..;5* haplotype (2.5%), but no other traces of Black African characteristic haplotypes are found. Although new RFLP haplotypes are described, DNA variation is similar to that reported in Caucasoids with a marked absence of restriction fragments characteristic of Black Africans. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Spanish and African contribution to the genetic pool of the Canary islanders: data from GM and KM haplotypes and RFLPs in the immunoglobulin IGHG loci

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References (45)

Publisher
Wiley
Copyright
Copyright © 1998 Wiley Subscription Services
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1046/j.1469-1809.1998.6210033.x
pmid
9659976
Publisher site
See Article on Publisher Site

Abstract

Data on the GM and KM haplotypes and RFLPs in the immunoglobulin IGHG loci are reported intending to evaluate the genetic contribution of the different populations (Europeans and Africans) who settled Tenerife Island. The GM and KM allotypic systems reveal an estimated European genetic admixture of 88%. The only possible African contribution is the presence of the GM*1,17;..;5* haplotype (2.5%), but no other traces of Black African characteristic haplotypes are found. Although new RFLP haplotypes are described, DNA variation is similar to that reported in Caucasoids with a marked absence of restriction fragments characteristic of Black Africans.

Journal

Annals of Human GeneticsWiley

Published: Jan 1, 1998

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