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Some further data on the joint segregation of HL‐A and haptoglobin

Some further data on the joint segregation of HL‐A and haptoglobin Some further data on the joint segregation of HL-A and haptoglobin BY W. F. BODMER,* J. G. BODMER,* A. COUKELL,* Department of Genetics B. VAN WEST Department of Pediatrics, Stanford University School of Medicine H. CANN, AND Data on t h e possible linkage between the HL-A and a-chain haptoglobin loci have been fully discussed in the preceding paper. In this note we present some further data based on an analysis of families typed as part of our contribution to the Fourth International Histocompatibility Testing Workshop (see Allen et al. 1970). The families were ascertained through normal healthy volunteers who were members of our cell panel, and all but one were Caucasian. They were chosen to be informative with respect to HL-A segregation and included one well-established and one probable recombinant between the LA and four loci of the HL-A system (Bodmer, Bodmer & Tripp, 1970). The fluorochromatic cytotoxicity assay, as described by Bodmer, Tripp & Bodmer (1967), was used for HL-A typing. Typing was done at least twice, in duplicate, using our standard HL-A sera, including some from the NIH Serum Bank (see e.g. Bodmer et al. 1970) and twice more as part of the Workshop, using http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Some further data on the joint segregation of HL‐A and haptoglobin

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References (14)

Publisher
Wiley
Copyright
Copyright © 1971 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1956.tb01389.x
Publisher site
See Article on Publisher Site

Abstract

Some further data on the joint segregation of HL-A and haptoglobin BY W. F. BODMER,* J. G. BODMER,* A. COUKELL,* Department of Genetics B. VAN WEST Department of Pediatrics, Stanford University School of Medicine H. CANN, AND Data on t h e possible linkage between the HL-A and a-chain haptoglobin loci have been fully discussed in the preceding paper. In this note we present some further data based on an analysis of families typed as part of our contribution to the Fourth International Histocompatibility Testing Workshop (see Allen et al. 1970). The families were ascertained through normal healthy volunteers who were members of our cell panel, and all but one were Caucasian. They were chosen to be informative with respect to HL-A segregation and included one well-established and one probable recombinant between the LA and four loci of the HL-A system (Bodmer, Bodmer & Tripp, 1970). The fluorochromatic cytotoxicity assay, as described by Bodmer, Tripp & Bodmer (1967), was used for HL-A typing. Typing was done at least twice, in duplicate, using our standard HL-A sera, including some from the NIH Serum Bank (see e.g. Bodmer et al. 1970) and twice more as part of the Workshop, using

Journal

Annals of Human GeneticsWiley

Published: Oct 1, 1971

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