Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Solvent‐induced Gel Formation Hypothesis for Natural Product Gelators with Polycyclic Structures

Solvent‐induced Gel Formation Hypothesis for Natural Product Gelators with Polycyclic Structures Natural products have long been used as pharmaceutical actives for the treatment of diseases. More recently, natural products with the ability to self‐assemble to form soft material‐gels, i.e. natural product gelators (NPGs), were discovered. This subverts our traditional insight into natural products as drugs and drives us to elucidate how NPGs form gels. Here, we interpret “why gel” from the perspective of solvents based on the basic theory of thermodynamics for liquids, and then propose the hypothesis of solvent‐induced gel formation in combination with the NPGs with polycyclic structures. This hypothesis provides a complete explanation of how the gelator and solvent play a role in the overall gel formation and helps us to more easily understand the gelation. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png ChemPlusChem Wiley

Solvent‐induced Gel Formation Hypothesis for Natural Product Gelators with Polycyclic Structures

Loading next page...
 
/lp/wiley/solvent-induced-gel-formation-hypothesis-for-natural-product-gelators-TV0xb6MbzW

References (42)

Publisher
Wiley
Copyright
© 2018 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim
ISSN
2192-6506
eISSN
2192-6506
DOI
10.1002/cplu.201800334
Publisher site
See Article on Publisher Site

Abstract

Natural products have long been used as pharmaceutical actives for the treatment of diseases. More recently, natural products with the ability to self‐assemble to form soft material‐gels, i.e. natural product gelators (NPGs), were discovered. This subverts our traditional insight into natural products as drugs and drives us to elucidate how NPGs form gels. Here, we interpret “why gel” from the perspective of solvents based on the basic theory of thermodynamics for liquids, and then propose the hypothesis of solvent‐induced gel formation in combination with the NPGs with polycyclic structures. This hypothesis provides a complete explanation of how the gelator and solvent play a role in the overall gel formation and helps us to more easily understand the gelation.

Journal

ChemPlusChemWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

There are no references for this article.