Access the full text.
Sign up today, get DeepDyve free for 14 days.
G. Kosolapoff (1953)
The Chemistry of Aliphatic Phosphonic Acids. I. Alkylation of Methanediphosphonic Acid1Journal of the American Chemical Society, 75
G. Keglevich, T. Novák, L. Vida, I. Greiner (2006)
Microwave irradiation as an alternative to phase transfer catalysis in the liquid-solid phase, solvent-free C-alkylation of active methylene containing substratesGreen Chemistry, 8
M. Lolli, L. Lazzarato, A. Stilo, R. Fruttero, A. Gasco (2002)
Michael addition of Grignard reagents to tetraethyl ethenylidenebisphosphonateJournal of Organometallic Chemistry, 650
M. Teulade, P. Savignac, E. Aboujaoude, Stéphane Liétge, N. Collignon (1986)
Alkylidènediphosphonates et vinylphosphonates: une démarche synthétiques sélective par voie carbanioniqueJournal of Organometallic Chemistry, 304
G. Keglevich, K. Majrik, L. Vida, I. Greiner (2008)
Microwave Irradiation as a Green Alternative to Phase Transfer Catalysis: Solid-Liquid Phase Alkylation of Active Methylene Containing Substrates Under Solvent-Free ConditionsLetters in Organic Chemistry, 5
L. Nguyen, E. Niesor, C. Bentzen (1987)
gem-Diphosphonate and gem-phosphonate-phosphate compounds with specific high density lipoprotein inducing activity.Journal of medicinal chemistry, 30 8
R. Ollivier, G. Sturitz, Legendre Jm, G. Jacolot, A. Turzo (1986)
Synthèse de nouveaux acides méthane diphosphoniques monosubstitués et étude in vivo chez l'animal de leurs complexes métalliques avec le technétium 99mEuropean Journal of Medicinal Chemistry, 21
Optimum conditions for the solid–liquid phase alkylation of tetraethyl methylenebisphosphonate are dependent on the nature of the alkyl halide. The benzylation with benzyl bromide takes place efficiently in boiling acetonitrile in the presence of potassium carbonate and a phase transfer catalyst. The ethylation with ethyl iodide was best accomplished under solventless microwave conditions in the presence of cesium carbonate and in the absence of an onium salt. The analogous propylation and butylation were complicated by the formation of mixed esters. © 2010 Wiley Periodicals, Inc. Heteroatom Chem 22:11–, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.20648
Heteroatom Chemistry – Wiley
Published: Jan 1, 2011
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.