Access the full text.
Sign up today, get DeepDyve free for 14 days.
GyÖrgy BuzsÁk (1998)
Memory consolidation during sleep: a neurophysiological perspective.Journal of sleep research, 7 Suppl 1
D. Contreras, M. Steriade (1996)
State-dependent fluctuations of low-frequency rhythms in corticothalamic networksNeuroscience, 76
K. Louie, M. Wilson (2001)
Temporally Structured Replay of Awake Hippocampal Ensemble Activity during Rapid Eye Movement SleepNeuron, 29
R. Stickgold (1998)
Sleep: off-line memory reprocessingTrends in Cognitive Sciences, 2
Shinya Suzuki, Grant Smith (1987)
Spontaneous EEG spikes in the normal hippocampus. I. Behavioral correlates, laminar profiles and bilateral synchrony.Electroencephalography and clinical neurophysiology, 67 4
J. Lieb, Stephen Woods, Antonio Siccardi, Paul Crandall, Donald Walter, Barbara Leake (1978)
Quantitative analysis of depth spiking in relation to seizure foci in patients with temporal lobe epilepsy.Electroencephalography and clinical neurophysiology, 44 5
D. Amaral (1990)
21 – Hippocampal Formation
F. Crick, G. Mitchison (1983)
The function of dream sleepNature, 304
C. Bazil, L. Castro, T. Walczak (2000)
Reduction of rapid eye movement sleep by diurnal and nocturnal seizures in temporal lobe epilepsy.Archives of neurology, 57 3
B. Malow, Xihong Lin, R. Kushwaha, M. Aldrich (1998)
Interictal Spiking Increases with Sleep Depth in Temporal Lobe EpilepsyEpilepsia, 39
J. Lisman (1997)
Bursts as a unit of neural information: making unreliable synapses reliableTrends in Neurosciences, 20
L. Ravagnati, E. Halgren, T. Babb, P. Crandall (1979)
Activity of human hippocampal formation and amygdala neurons during sleep.Sleep, 2 2
G. Holt, William Softky, C. Koch, R. Douglas (1996)
Comparison of discharge variability in vitro and in vivo in cat visual cortex neurons.Journal of neurophysiology, 75 5
T. Otto, H. Eichenbaum, C. Wible, S. Wiener (1991)
Learning‐related patterns of CA1 spike trains parallel stimulation parameters optimal for inducing hippocampal long‐term potentiationHippocampus, 1
M. Steriade (1999)
Coherent oscillations and short-term plasticity in corticothalamic networksTrends in Neurosciences, 22
S. Suzuki, Grant Smith (1985)
Burst characteristics of hippocampal complex spike cells in the awake ratExperimental Neurology, 89
L. Squire, S. Zola (1996)
Structure and function of declarative and nondeclarative memory systems.Proceedings of the National Academy of Sciences of the United States of America, 93 24
T. Kodama, H. Mushiake, K. Shima, H. Nakahama, Mitsuaki Yamamoto (1989)
Slow fluctuations of single unit activities of hippocampal and thalamic neurons in cats. I. Relation to natural sleep and alert statesBrain Research, 487
E. Wolpert (1969)
A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects.Archives of General Psychiatry, 20
B. Colder, C. Wilson, R. Frysinger, R. Harper, J. Engel (1996)
Interspike intervals during interictal periods in human temporal lobe epilepsyBrain Research, 719
S. Suzuki, G. Smith (1988)
Spontaneous EEG spikes in the normal hippocampus. IV. Effects of medial septum and entorhinal cortex lesions.Electroencephalography and clinical neurophysiology, 70 1
E. Nofzinger, M. Mintun, M. Wiseman, D. Kupfer, R. Moore (1997)
Forebrain activation in REM sleep: an FDG PET study 1 Presented in abstract form at the Society for Neuroscience Meeting, 1996. 1Brain Research, 770
A. Ylinen, A. Bragin, Z. Nadasdy, G. Jandó, I. Szabó, A. Sik, G. Buzsáki (1995)
Sharp wave-associated high-frequency oscillation (200 Hz) in the intact hippocampus: network and intracellular mechanisms, 15
A. Draguhn, R. Traub, A. Bibbig, D. Schmitz (2000)
Ripple (∼200-Hz) Oscillations in Temporal StructuresJournal of Clinical Neurophysiology, 17
J. Csicsvari, H. Hirase, András Czurkó, Akira Mamiya, G. Buzsáki (1999)
Oscillatory Coupling of Hippocampal Pyramidal Cells and Interneurons in the Behaving RatThe Journal of Neuroscience, 19
P. Maquet, C. Degueldre, G. Delfiore, J. Aerts, Jean-Marie Péters, A. Luxen, G. Franck (1997)
Functional Neuroanatomy of Human Slow Wave SleepThe Journal of Neuroscience, 17
J. Ranck (1973)
Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. I. Behavioral correlates and firing repertoires.Experimental neurology, 41 2
A. Rechtschaffen (2015)
Current Perspectives on the Function of SleepPerspectives in Biology and Medicine, 41
J. Lenman (1975)
THE HUMAN NERVOUS SYSTEMJournal of Neurology, Neurosurgery & Psychiatry, 38
M. Steriade, D. Contreras, F. Amzica, lgor Timofeev (1996)
Synchronization of fast (30-40 Hz) spontaneous oscillations in intrathalamic and thalamocortical networks, 16
P. Huerta, J. Lisman (1995)
Bidirectional synaptic plasticity induced by a single burst during cholinergic theta oscillation in CA1 in vitroNeuron, 15
G. Buzsáki, Leung S., C. Vanderwolf (1983)
Cellular bases of hippocampal EEG in the behaving ratBrain Research Reviews, 6
I. Fried, C. Wilson, N. Maidment, J. Engel, Eric Behnke, Tony Fields, Katherine Macdonald, Jack Morrow, L. Ackerson (1999)
Cerebral microdialysis combined with single-neuron and electroencephalographic recording in neurosurgical patients. Technical note.Journal of neurosurgery, 91 4
Mathew Wilson, B. McNaughton (1994)
Reactivation of hippocampal ensemble memories during sleep.Science, 265 5172
G. Gigli, J. Gotman (1992)
Effects of Seizures, Kindling, and Carbamazepine on Sleep Organization in CatsEpilepsia, 33
Dominique Debanne, B. Gähwiler, Scott Thompson (1996)
Cooperative interactions in the induction of long-term potentiation and depression of synaptic excitation between hippocampal CA3-CA1 cell pairs in vitro.Proceedings of the National Academy of Sciences of the United States of America, 93 20
M. Abeles (1982)
Quantification, smoothing, and confidence limits for single-units' histogramsJournal of Neuroscience Methods, 5
A. Telfeian, D. Spencer, A. Williamson (1999)
Lack of correlation between neuronal hyperexcitability and electrocorticographic responsiveness in epileptogenic human neocortex.Journal of neurosurgery, 90 5
M. Sammaritano, G. Gigli, J. Gotman (1991)
Interictal spiking during wakefulness and sleep and the localization of foci in temporal lobe epilepsyNeurology, 41
T. Weyand, Michael Boudreaux, W. Guido (2001)
Burst and tonic response modes in thalamic neurons during sleep and wakefulness.Journal of neurophysiology, 85 3
Engel Engel (1996)
Current concepts: surgery for seizuresN Engl J Med, 334
J. Chrobak, G. Buzsáki (1996)
High-Frequency Oscillations in the Output Networks of the Hippocampal–Entorhinal Axis of the Freely Behaving RatThe Journal of Neuroscience, 16
H. Kudrimoti, C. Barnes, B. McNaughton (1999)
Reactivation of Hippocampal Cell Assemblies: Effects of Behavioral State, Experience, and EEG DynamicsThe Journal of Neuroscience, 19
S. Cobb, E. Buhl, K. Halasy, O. Paulsen, P. Somogyi (1995)
Synchronization of neuronal activity in hippocampus by individual GABAergic interneuronsNature, 378
M. Shouse, M. Sterman (1983)
‘Kindling’ a sleep disorder: degree of sleep pathology predicts kindled seizure susceptibility in catsBrain Research, 271
S. Suzuki, Grant Smith (1985)
Single-cell activity and synchronous bursting in the rat hippocampus during waking behavior and sleepExperimental Neurology, 89
Mitsuaki Yamamoto, H. Nakahama, K. Shima, T. Kodama, H. Mushiake (1986)
Markov-dependency and spectral analyses on spike-counts in mesencephalic reticular neurons during sleep and attentive statesBrain Research, 366
A. Wyler, G. Ojemann, A. Ward (1982)
Neurons in human epileptic cortex: Correlation between unit and EEG activityAnnals of Neurology, 11
Hiroharu Noda, S. Manohar, W. Adey (1969)
Spontaneous activity of cat hippocampal neurons in sleep and wakefulness.Experimental neurology, 24 2
H. Duvernoy (1998)
The Human Hippocampus
Andreas Draguhn, R. Traub, A. Bibbig, Dietmar Schmitz (2000)
Ripple (approximately 200-Hz) oscillations in temporal structures.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 17 4
W. Skaggs, B. McNaughton (1996)
Replay of Neuronal Firing Sequences in Rat Hippocampus During Sleep Following Spatial ExperienceScience, 271
K. Britten, M. Shadlen, W. Newsome, J. Movshon (1993)
Responses of neurons in macaque MT to stochastic motion signalsVisual Neuroscience, 10
G. Buzsáki (1986)
Hippocampal sharp waves: Their origin and significanceBrain Research, 398
William Softky, C. Koch (1993)
The highly irregular firing of cortical cells is inconsistent with temporal integration of random EPSPs, 13
G. Poe, D. Nitz, B. McNaughton, C. Barnes (2000)
Experience-dependent phase-reversal of hippocampal neuron firing during REM sleepBrain Research, 855
H. Eichenbaum (1999)
The hippocampus and mechanisms of declarative memoryBehavioural Brain Research, 103
J. Engel (1996)
Surgery for seizures.The New England journal of medicine, 334 10
Although there are numerous non‐primate studies of the single neuron correlates of sleep‐related hippocampal EEG patterns, very limited hippocampal neuronal data are available for correlation with human sleep. We recorded human hippocampal single neuron activity in subjects implanted with depth electrodes required for medical diagnosis and quantitatively evaluated discharge activity from each neuron during episodes of wakefulness (Aw), combined stage 3 and 4 slow‐wave sleep (SWS), and rapid eye movement (REM) sleep. The mean firing rate of the population of single neurons was significantly higher during SWS and Aw compared with REM sleep (p = 0.002; p < 0.0001). In addition, burst firing was significantly greater during SWS compared with Aw (p = 0.001) and REM sleep (p < 0.0001). The synchronized state of SWS and associated high‐frequency burst discharge found in human hippocampus may subserve functions similar to those reported in non‐primate hippocampus that require burst firing to induce synaptic modifications in hippocampal circuitry and in hippocampal projections to neocortical targets that participate in memory consolidation. Hippocampus 2002;12:724–734. © 2002 Wiley‐Liss, Inc.
Hippocampus – Wiley
Published: Jan 1, 2002
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.