Access the full text.
Sign up today, get DeepDyve free for 14 days.
E.J.H. Jones, T. Gliga, R. Bedford, T. Charman, M.H. Johnson (2014)
Developmental pathways to autism: A review of prospective studies of infants at risk, 39
T. Pilowsky, N. Yirmiya, R.S. Shalev, V. Gross‐Tsur (2003)
Language abilities of siblings of children with autism, 44
E. Semel, E.H. Wiig, W.A. Secord (2003)
Clinical evaluation of language fundamentals, fourth edition (CELF‐4)
Johanna Carpenter, Deborah Drabick (2010)
Early Child Development and Care
S.S. Lee, B.B. Lahey, E.B. Owens, S.P. Hinshaw (2008)
Few preschool boys and girls with ADHD are well‐adjusted during adolescence, 36
P. Ross, M. Cuskelly (2006)
Adjustment, sibling problems and coping strategies of brothers and sisters of children with autistic spectrum disorder, 31
E. Drumm, S. Bryson, L. Zwaigenbaum, J. Brian (2015)
Language‐related abilities in ‘unaffected’ school‐age siblings of children with ASD, 18
J.L. Carpenter, D.A.G. Drabick (2011)
Co‐occurrence of linguistic and behavioural difficulties in early childhood: A developmental psychopathology perspective, 181
E. Drumm, J. Brian (2014)
The developing language abilities and increased risks of ‘unaffected’ siblings of children with autism spectrum disorder, 3
(1996)
Executive dysfunction as an underlying mechanism of behavior and language problems in attention deficit hyperactivity disorder
E. Fombonne, P. Bolton, J. Prior, H. Jordan, M. Rutter (1997)
A family study of autism: Cognitive patterns and levels in parents and siblings, 38
D. Messinger, G.S. Young, S. Ozonoff, K. Dobkins, A. Carter, L. Zwaigenbaum, M. Sigman (2013)
Beyond autism: A baby siblings research consortium study of high‐risk children at three years of age, 52
M.C. Kasius, R.F. Ferdinand, H. den Berg, F.C. Verhulst (1997)
Associations between different diagnostic approaches for child and adolescent psychopathology, 38
M. Bellina, P. Brambilla, M. Garzitto, G.A.L. Negri, M. Molteni, M. Nobile (2013)
The ability of CBCL DSM‐oriented scales to predict DSM‐IV diagnoses in a referred sample of children and adolescents, 22
J.N. Constantino, C. Lajonchere, M. Lutz, T. Gray, A. Abbacchi, K. McKenna, R.D. Todd (2006)
Autistic social impairment in the siblings of children with pervasive developmental disorders, 163
T.M. Achenbach, L. Rescorla (2000)
Child behavior checklist for ages 1½‐5
C.D. Elliott (2007)
Differential ability scales – second edition (DAS‐II)
I. Gamliel, N. Yirmiya, D.H. Jaffe, O. Manor, M. Sigman (2009)
Developmental trajectories in siblings of children with autism: Cognition and language from 4 months to 7 years, 39
A.J. Schwichtenberg, G.S. Young, T. Hutman, A. Iosif, M. Sigman, S.J. Rogers, S. Ozonoff (2013)
Behavior and sleep problems in children with a family history of autism, 6
K. Gillespie-Lynch, Allie Khalulyan, Mithi Rosario, B. McCarthy, Lovella Gomez, M. Sigman, T. Hutman (2015)
Is early joint attention associated with school-age pragmatic language?Autism, 19
R. Tannock, R. Shachar (1996)
Language, learning, & behavior disorders: Developmental, biological, & clinical perspectives
N. Quintero, L.L. McIntyre (2010)
Sibling adjustment and maternal well‐being: An examination of families with and without a child with an autism spectrum disorder, 25
E.J. Costello, S. Mustillo, A. Erkanil, G. Keeler, A. Angold (2003)
Prevalence and development of psychiatric disorders in childhood and adolescence, 60
S. Ozonoff, G.S. Young, A. Carter, D. Messinger, N. Yirmiya, L. Zwaigenbaum, W.L. … Stone (2011)
Recurrence risk for autism spectrum disorders: A Baby Siblings Research Consortium study, 128
J.N. Constantino, C.P. Gruber (2005)
Social responsiveness scale
E. Sucksmith, I. Roth, R.A. Hoekstra (2011)
Autistic traits below the clinical threshold: Re‐examining the broader autism phenotype in the 21st century, 21
S. Verté, H. Roeyers, A. Buysse (2003)
Behavioural problems, social competence and self‐concept in siblings of children with autism, 29
T. Ford, R. Goodman, H. Meltzer (2003)
The British child and adolescent mental health survey 1999: The prevalence of DSM‐IV disorders, 42
R.P. Hastings (2003)
Brief report: Behavioral adjustment of siblings of children with autism, 33
P. Howlin, P. Moss, S. Savage, P. Bolton, M. Rutter (2015)
Outcomes in adult life among siblings of individuals with autism, 45
C. Lord, S. Risi, L. Lambrecht, E.H. Cook, B.L. Leventhal, P.C. DiLavore, M. Rutter (2000)
The autism diagnostic observation schedule – generic: A standard measure of social and communication deficits associated with the spectrum of autism, 30
M. Miller, G.S. Young, T. Hutman, S. Johnson, A.J. Schwichtenberg, S. Ozonoff (2015)
Early pragmatic language difficulties in siblings of children with autism: Implications for DSM‐5 social communication disorder, 56
M.A. Petalas, R.P. Hastings, S. Nash, T. Lloyd, A. Dowey (2009)
Emotional and behavioural adjustment in siblings of children with intellectual disability with and without autism, 13
R.F. Ferdinand, J.H. Visser, K.N. Hoogerheide, J. Ende, M.C. Kasius, H.M. Koot, F.C. Verhulst (2004)
Improving estimation of the prognosis of child psychopathology; combination of DSM‐III‐R‐/DISC diagnoses and CBCL scores, 45
K. Gillespie‐Lynch, A. Khalulyan, M. Del Rosario, B. McCarthy, L. Gomez, M. Sigman, T. Hutman (2013)
Is early joint attention associated with school‐age pragmatic language among siblings of children with, 19
N. Ben‐Yizhak, N. Yirmiya, I. Seidman, R. Alon, C. Lord, M. Sigman (2011)
Pragmatic language and school related linguistic abilities in siblings of children with autism, 41
M. Rutter, A. Bailey, C. Lord (2003)
Social communication questionnaire: Manual
Denise Thomas, C. Anne (2010)
Cognitive profiles for school -age children with Attention-Deficit/Hyperactivity Disorder or with Mathematics Disorder on the Differential Ability Scales -Second Edition (DAS-II)
A. Bailey, S. Palferman, L. Heavey, A. LeCouteur (1998)
Autism: The phenotype in relatives, 28
S. Ozonoff, G.S. Young, A. Belding, M. Hill, A. Hill, T. Hutman, A.M. Iosif (2014)
The broader autism phenotype in infancy: When does it emerge?, 53
J. Piven, P. Palmer (1999)
Psychiatric disorder and the broad autism phenotype: Evidence from a family study of multiple‐incidence autism families, 156
V. Gizzonio, P. Avanzini, M. Fabbri‐Destro, C. Campi, G. Rizzolatti (2014)
Cognitive abilities in siblings of children with autism spectrum disorders, 232
Studies of infants at risk for autism spectrum disorder (ASD) have proliferated, but few of these samples have been followed longer‐term. We conducted a follow‐up study, at age 5.5–9 years, of younger siblings of children with ASD (high‐risk group, n = 79) or typical development (low‐risk group, n = 60), originally recruited as infants. Children with ASD were excluded because of the focus on understanding the range of non‐ASD outcomes among high‐risk siblings. Using examiner ratings, parent ratings, and standardized assessments, we evaluated differences in clinical outcomes, psychopathology symptoms, autism symptoms, language skills, and nonverbal cognitive abilities. After adjusting for covariates, the high‐risk group had increased odds of any clinically elevated/impaired score across measures relative to the low‐risk group (43% vs. 12%, respectively). The high‐risk group also had increased odds of examiner‐rated Clinical Concerns (CC) outcomes (e.g., ADHD concerns, broader autism phenotype, speech‐language difficulties, anxiety/mood problems, learning problems) relative to the low‐risk group (38% vs. 13%, respectively). The high‐risk group with CC outcomes had higher parent‐reported psychopathology and autism symptoms, and lower directly‐assessed language skills, than the Low‐Risk Typically Developing (TD) and High‐Risk TD groups, which did not differ. There were no differences in nonverbal cognitive skills. For some in the high‐risk group, clinical concerns persisted from early childhood, whereas for others clinical concerns were first evident at school‐age. Results suggest continued vulnerability in at least a subgroup of school‐age children with a family history of ASD and suggest that this population may benefit from continued screening and monitoring into the school‐age years. Autism Res 2016, 9: 632–642. © 2015 International Society for Autism Research, Wiley Periodicals, Inc.
Autism Research – Wiley
Published: Jun 1, 2016
Keywords: ; ; ; ;
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.