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Sampling distribution of summary linkage disequilibrium measures

Sampling distribution of summary linkage disequilibrium measures The design of association studies is critically dependent upon the extent of linkage disequilibrium (LD) across different genomic regions, often summarised in terms of the mean absolute value of summary linkage disequilibrium measures. The two most commonly used measures are D′ for estimating the magnitude or extent of LD, and Δ which is directly proportional to the power of LD mapping. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Sampling distribution of summary linkage disequilibrium measures

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References (13)

Publisher
Wiley
Copyright
Copyright © 2002 Wiley Subscription Services
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1046/j.1469-1809.2002.00108.x
Publisher site
See Article on Publisher Site

Abstract

The design of association studies is critically dependent upon the extent of linkage disequilibrium (LD) across different genomic regions, often summarised in terms of the mean absolute value of summary linkage disequilibrium measures. The two most commonly used measures are D′ for estimating the magnitude or extent of LD, and Δ which is directly proportional to the power of LD mapping.

Journal

Annals of Human GeneticsWiley

Published: Jan 1, 2002

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