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The design of association studies is critically dependent upon the extent of linkage disequilibrium (LD) across different genomic regions, often summarised in terms of the mean absolute value of summary linkage disequilibrium measures. The two most commonly used measures are D′ for estimating the magnitude or extent of LD, and Δ which is directly proportional to the power of LD mapping.
Annals of Human Genetics – Wiley
Published: Jan 1, 2002
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