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Yoshinori Kobayashi*, Y. Nakano, M. Kizaki, Kiyoko Hoshikuma, Y. Yokoo, T. Kamiya (2001)
Capsaicin-Like Anti-Obese Activities of Evodiamine from Fruits of Evodia rutaecarpa, a Vanilloid Receptor AgonistPlanta Medica, 67
P. Arockiam, C. Bruneau, P. Dixneuf (2012)
Ruthenium(II)-catalyzed C-H bond activation and functionalization.Chemical reviews, 112 11
K. Fujita, Kazunari Yamamoto, R. Yamaguchi (2002)
Oxidative cyclization of amino alcohols catalyzed by a CpIr complex. Synthesis of indoles, 1,2,3,4-tetrahydroquinolines, and 2,3,4,5-tetrahydro-1-benzazepine.Organic letters, 4 16
L. Ackermann (2010)
Metal-catalyzed direct alkylations of (hetero)arenes via C-H bond cleavages with unactivated alkyl halides.Chemical communications, 46 27
C. Ferrando, J. Foy, C. Pratt, J. Purvis (1981)
On the pharmacological actions of a diuretic, fenquizone, with particular reference to its site of actionJournal of Pharmacy and Pharmacology, 33
Xiao Chen, K. Engle, Donghui Wang, Jin-Quan Yu (2009)
Palladium(II)‐katalysierte C‐H‐Aktivierung/C‐C‐Kreuzkupplung: Vielseitigkeit und AnwendbarkeitAngewandte Chemie, 121
Chunyu Song, Shuanglin Qu, Yuan Tao, Yanfeng Dang, Zhi‐Xiang Wang (2014)
DFT Mechanistic Study of RuII-Catalyzed Amide Synthesis from Alcohol and Nitrile Unveils a Different Mechanism for Borrowing HydrogenACS Catalysis, 4
Junichiro Yamaguchi, A. Yamaguchi, K. Itami (2012)
C-H bond functionalization: emerging synthetic tools for natural products and pharmaceuticals.Angewandte Chemie, 51 36
Zhuangzhi Shi, S. Ding, Yu-xin Cui, N. Jiao (2009)
A palladium-catalyzed oxidative cycloaromatization of biaryls with alkynes using molecular oxygen as the oxidant.Angewandte Chemie, 48 42
Bin Li, T. Roisnel, C. Darcel, P. Dixneuf (2012)
Cyclometallation of arylimines and nitrogen-containing heterocycles via room-temperature C-H bond activation with arene ruthenium(II) acetate complexes.Dalton transactions, 41 36
Bin Li, Huiliang Feng, N. Wang, Jianfeng Ma, Hai-bin Song, Shansheng Xu, Baiquan Wang (2012)
Ruthenium-catalyzed oxidative coupling/cyclization of isoquinolones with alkynes through C-H/N-H activation: mechanism study and synthesis of dibenzo[a,g]quinolizin-8-one derivatives.Chemistry, 18 40
D. Colby, A. Tsai, R. Bergman, J. Ellman (2012)
Rhodium catalyzed chelation-assisted C-H bond functionalization reactions.Accounts of chemical research, 45 6
Sean Clapham, A. Hadžović, R. Morris (2004)
Mechanisms of the H2-hydrogenation and transfer hydrogenation of polar bonds catalyzed by ruthenium hydride complexesCoordination Chemistry Reviews, 248
D. Colby, R. Bergman, J. Ellman (2010)
Rhodium-catalyzed C-C bond formation via heteroatom-directed C-H bond activation.Chemical reviews, 110 2
B. Stokes, T. Driver (2011)
Transition Metal-Catalyzed Formation of N-Heterocycles via Aryl- or Vinyl C–H Bond AminationEuropean Journal of Organic Chemistry, 2011
Junichiro Yamaguchi, Atsushi Yamaguchi, Kenichiro Itami (2012)
Funktionalisierung von C‐H‐Bindungen: neue Synthesemethoden für Naturstoffe und PharmazeutikaAngewandte Chemie, 124
M. Reddy, R. Manikandan, M. Jeganmohan (2013)
Ruthenium-catalyzed aerobic oxidative cyclization of aromatic and heteroaromatic nitriles with alkynes: a new route to isoquinolones.Chemical communications, 49 54
Will Gutekunst, P. Baran (2011)
C-H functionalization logic in total synthesis.Chemical Society reviews, 40 4
Jie Li, M. John, L. Ackermann (2014)
Amidines for versatile ruthenium(II)-catalyzed oxidative C-H activations with internal alkynes and acrylates.Chemistry, 20 18
T. Satoh, M. Miura (2010)
Oxidative coupling of aromatic substrates with alkynes and alkenes under rhodium catalysis.Chemistry, 16 37
B. Trost (1995)
Atomökonomische Synthesen – eine Herausforderung in der Organischen Chemie: die Homogenkatalyse als wegweisende MethodeAngewandte Chemie, 107
Jianguang Zhou, Jie Fang (2011)
One-pot synthesis of quinazolinones via iridium-catalyzed hydrogen transfers.The Journal of organic chemistry, 76 19
Y. Hong, W. Lee, Seung Lee, J. Son, Hye-Lin Kim, J. Nam, Y. Kwon, Y. Jahng (2010)
Synthesis and biological properties of benzo-annulated rutaecarpines.Biological & pharmaceutical bulletin, 33 10
Bin Li, N. Wang, Yu-Feng Liang, Shansheng Xu, Baiquan Wang (2013)
Ruthenium-catalyzed pyrrole synthesis via oxidative annulation of enamides and alkynes.Organic letters, 15 1
Lianhui Wang, L. Ackermann (2013)
Versatile pyrrole synthesis through ruthenium(II)-catalyzed alkene C-H bond functionalization on enamines.Organic letters, 15 1
Ching-Zong Luo, Parthasarathy Gandeepan, Chien‐Hong Cheng (2013)
A convenient synthesis of quinolizinium salts through Rh(III) or Ru(II)-catalyzed C-H bond activation of 2-alkenylpyridines.Chemical communications, 49 76
L. Ackermann, R. Vicente (2010)
Ruthenium-catalyzed direct arylations through C-H bond cleavages.Topics in current chemistry, 292
N. Yoshikai, Ye Wei (2013)
Synthesis of Pyrroles, Indoles, and Carbazoles through Transition‐Metal‐Catalyzed CH FunctionalizationAsian Journal of Organic Chemistry, 2
Jie Li, L. Ackermann (2014)
Ruthenium-catalyzed oxidative alkyne annulation by C–H activation on ketiminesTetrahedron, 70
Timothy Newhouse, P. Baran, R. Hoffmann (2009)
The economies of synthesis.Chemical Society reviews, 38 11
B. Trost (1995)
Atom Economy—A Challenge for Organic Synthesis: Homogeneous Catalysis Leads the WayAngewandte Chemie, 34
B. Trost (1991)
The atom economy--a search for synthetic efficiency.Science, 254 5037
T. Mei, Lei Kou, Sandy Ma, K. Engle, jin-quan yu (2012)
Heterocycle Formation via Palladium-Catalyzed C-H Functionalization.Synthesis, 44 12
V. Thirunavukkarasu, S. Kozhushkov, L. Ackermann (2014)
C-H nitrogenation and oxygenation by ruthenium catalysis.Chemical communications, 50 1
N. Kuhl, Nils Schröder, F. Glorius (2014)
Formal SN‐Type Reactions in Rhodium(III)‐Catalyzed CH Bond ActivationAdvanced Synthesis & Catalysis, 356
Hui Lu, Qin Yang, Yirong Zhou, Yanqin Guo, Z. Deng, Q. Ding, Yiyuan Peng (2014)
Cross-coupling/annulations of quinazolones with alkynes for access to fused polycyclic heteroarenes under mild conditions.Organic & biomolecular chemistry, 12 5
Noah Burns, Phil Baran, R. Hoffmann (2009)
Redoxkonomie in der organischen SyntheseAngewandte Chemie
Sachiyo Nakanowatari, L. Ackermann (2014)
Ruthenium(II)-catalyzed synthesis of isochromenes by C-H activation with weakly coordinating aliphatic hydroxyl groups.Chemistry, 20 18
N. Burns, P. Baran, R. Hoffmann (2009)
Redox economy in organic synthesis.Angewandte Chemie, 48 16
Johnathon Dooley, Suresh Chidipudi, H. Lam (2013)
Catalyst-controlled divergent C-H functionalization of unsymmetrical 2-aryl cyclic 1,3-dicarbonyl compounds with alkynes and alkenes.Journal of the American Chemical Society, 135 29
Xiao Chen, K. Engle, Dong-Hui Wang, jin-quan yu (2009)
Palladium(II)-catalyzed C-H activation/C-C cross-coupling reactions: versatility and practicality.Angewandte Chemie, 48 28
J. Wencel‐Delord, F. Glorius (2013)
C-H bond activation enables the rapid construction and late-stage diversification of functional molecules.Nature chemistry, 5 5
L. Ackermann (2014)
Carboxylate-assisted ruthenium-catalyzed alkyne annulations by C-H/Het-H bond functionalizations.Accounts of chemical research, 47 2
Cong-Hui Wang, S. Rakshit, F. Glorius (2010)
Palladium-catalyzed intermolecular decarboxylative coupling of 2-phenylbenzoic acids with alkynes via C-H and C-C bond activation.Journal of the American Chemical Society, 132 40
S. Meegalla, G. Stevens, C. Mcqueen, A. Chen, C. Yu, L. Liu, L. Barrows, E. LaVoie (1994)
Synthesis and pharmacological evaluation of isoindolo[1,2-b]quinazolinone and isoindolo[2,1-a]benzimidazole derivatives related to the antitumor agent batracylin.Journal of medicinal chemistry, 37 20
Simon Whitney, R. Grigg, Andrew Derrick, Ann Keep (2007)
[Cp*IrCl2]2-catalyzed indirect functionalization of alcohols: novel strategies for the synthesis of substituted indoles.Organic letters, 9 17
Jiang Nan, Z. Zuo, Lei Luo, Lu Bai, Huayu Zheng, Yini Yuan, Jingjing Liu, X. Luan, Yaoyu Wang (2013)
Ru(II)-catalyzed vinylative dearomatization of naphthols via a C(sp2)-H bond activation approach.Journal of the American Chemical Society, 135 46
Youngchul Park, Incheol Jeon, Seohyun Shin, J. Min, P. Lee (2013)
Ruthenium-catalyzed C-H activation/cyclization for the synthesis of phosphaisocoumarins.The Journal of organic chemistry, 78 20
S. Kozhushkov, L. Ackermann (2013)
Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C–H bond functionalizationChemical Science, 4
G. Song, Fen Wang, Xingwei Li (2012)
C-C, C-O and C-N bond formation via rhodium(III)-catalyzed oxidative C-H activation.Chemical Society reviews, 41 9
L. Ballou, E. Selinger, J. Choi, D. Drueckhammer, R. Lin (2007)
Inhibition of Mammalian Target of Rapamycin Signaling by 2-(Morpholin-1-yl)pyrimido[2,1-α]isoquinolin-4-one*Journal of Biological Chemistry, 282
S. Mhaske, N. Argade (2006)
The Chemistry of Recently Isolated Naturally Occurring Quinazolinone AlkaloidsChemInform, 38
S. Chiba (2012)
Cu–Rh Redox Relay Catalysts for Synthesis of Azaheterocycles via C–H FunctionalizationChemistry Letters, 41
One single catalyst, [RuCl2(p‐cymene)]2, was used for oxidative dehydrogenation followed by cross‐coupling/annulation reactions to access diversely decorated N‐fused polycyclic heteroarenes from dihydroquinazolinones and alkynes. This one‐pot method does not require purification of intermediates or addition of copper salts. The synergistic use of molecular oxygen as the oxidant highlights the sustainable aspect of this method.
Asian Journal of Organic Chemistry – Wiley
Published: May 1, 2015
Keywords: ; ; ; ;
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