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Ruthenium as a Single Catalyst for Two Steps: One‐Pot Ruthenium(II)‐Catalyzed Aerobic Oxidative Dehydrogenation of Dihydroquinazolinones and Cross‐Coupling/Annulation to give N‐Fused Polycyclic Heteroarenes

Ruthenium as a Single Catalyst for Two Steps: One‐Pot Ruthenium(II)‐Catalyzed Aerobic Oxidative... One single catalyst, [RuCl2(p‐cymene)]2, was used for oxidative dehydrogenation followed by cross‐coupling/annulation reactions to access diversely decorated N‐fused polycyclic heteroarenes from dihydroquinazolinones and alkynes. This one‐pot method does not require purification of intermediates or addition of copper salts. The synergistic use of molecular oxygen as the oxidant highlights the sustainable aspect of this method. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Asian Journal of Organic Chemistry Wiley

Ruthenium as a Single Catalyst for Two Steps: One‐Pot Ruthenium(II)‐Catalyzed Aerobic Oxidative Dehydrogenation of Dihydroquinazolinones and Cross‐Coupling/Annulation to give N‐Fused Polycyclic Heteroarenes

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References (53)

Publisher
Wiley
Copyright
Copyright © 2015 Wiley Subscription Services, Inc., A Wiley Company
ISSN
2193-5807
eISSN
2193-5815
DOI
10.1002/ajoc.201500025
Publisher site
See Article on Publisher Site

Abstract

One single catalyst, [RuCl2(p‐cymene)]2, was used for oxidative dehydrogenation followed by cross‐coupling/annulation reactions to access diversely decorated N‐fused polycyclic heteroarenes from dihydroquinazolinones and alkynes. This one‐pot method does not require purification of intermediates or addition of copper salts. The synergistic use of molecular oxygen as the oxidant highlights the sustainable aspect of this method.

Journal

Asian Journal of Organic ChemistryWiley

Published: May 1, 2015

Keywords: ; ; ; ;

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