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F. Giannelli, R. Howlett (1966)
The identification of the chromosomes of the D group (13-15) Denver: an autoradiographic and measurement study.Cytogenetics, 5 3
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Chronology and pattern of human
Ockey Ockey (1969)
The position of chromosomes at metaphase in human fibroblasts and their DNA synthesis behaviourChromosoma. Berl., 27
P. Moorhead, P. Nowell, W. Mellman, D. Battips, D. Hungerford (1960)
Chromosome preparations of leukocytes cultured from human peripheral blood.Experimental cell research, 20
J. German (1969)
AUTORADIOGRAPHIC STUDIES OF HUMAN CHROMOSOMES. I. A REVIEW.
N. Takagi, A. Sandberg (1968)
Chronology and pattern of human chromosome replicationCytogenetic and Genome Research, 7
Kikuchi Kikuchi, Sandberg Sandberg (1964)
Chronology and pattern of human chromosome replication. 1. Blood leukocytes in normal subjectsJ. Nat. Cancer Inst., 3
A. Lima-de-faria, N. Bianchi, P. Nowell (2009)
Patterns of chromosome replication in a patient with chronic granulocytic leukemia.Hereditas, 58 1
A. Capoa, D. Miller, O. Miller, W. Breg (1968)
Asynchronous DNA Replication and Discordant Length of Homologous Autosomes demonstrated by the Use of MarkersNature, 220
(1966)
Autoradiographic studies of human chromosomes . 1 . A review . Proc . 3 rd Intemat
H. Chandra, D. Hungerford (1967)
Identification of the human X chromosome: a reconciliation between results obtained from morphological and from radioautographic studies.Annales de genetique, 10 1
B. Herreros, A. Guerro, E. Romo (1966)
COLCEMID-INDUCED POLYPLOIDYThe Lancet, 288
(1960)
DNA synthesis in chromosomes of cultured leucocytes from two marsupial MOORHEAD
J. Graves (1967)
DNA synthesis in chromosomes of cultured leucocytes from two marsupial species.Experimental cell research, 46 1
C. Smith (1957)
On the estimation of intra-class correlation.Annals of human genetics, 21 4
Ockey Ockey, Wennström Wennström, Chapelle Chapelle (1966)
Isochromosome‐X in man. Part. IIHereditas, Lund., 54
A. Sandberg, N. Takagi, M. Schmidt, I. Bross (1968)
Chronology and pattern of human chromosome replication. IX. Metasynchronous DNA replication in homologs.Cytogenetics, 7 4
Atkins Atkins, Santesson Santesson (1966)
Chromosome DNA synthesis in cultured normal human female skin cellsHereditas, Lund., 55
BY F. GIANNELLI, B. HERREROS," AND C. A. B. SMITH Paediatric Research Unit, Guy's Hospital, London, X.E. 1 and Crcclton Laboratory, University College, London, W.C. 1 Recent papers (Atkins & Santesson, 1966; Ockey, Wennstrom & De La Chapelle, 1966; Chandra & Hungerford, 1967 ;German, 1966; Kikuchi & Sandberg, 1964; Lima-de-Faria,Bianchi & Nowell, 1967; Marshall Graves, 1967; Sandberg et al. 1968; De Capoa etal. 1968; Ockey, 1969) have discussed the length differences between homologous chromosomes and the similarity of their DNA synthesis. Further understanding may be obtained from the study of endoreduplicated and tetraploid cells. In these cells the whole chromosome complement is doubled. Thus, for example, there are four number 1 chromosomes, consisting of two homologous pairs of 'sister chromosomes'. Each of the two sister chromosomes are genetically alike. These chromosomes lie close together in endoreduplications (Fig. 1) but much less close in tetraploids. The question therefore arises whether in endoreduplications sister chromosomesdiffer from each other by a lesser extent than non-sister chromosomes, and if so by how much? If sister chromosomes turn out to be very similar, then either the length is controlled mainly by the genes on the chromosome or the close proximity and, therefore, similm
Annals of Human Genetics – Wiley
Published: May 1, 1970
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