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Regional localization of a human cytochrome P‐450 ( CYP1 ) to chromosome 19q 13.1–13.3

Regional localization of a human cytochrome P‐450 ( CYP1 ) to chromosome 19q 13.1–13.3 Summary A phenobarbitone inducible cytochrome P‐450 gene family (CYP1) has recently been localized to chromosome 19q13.1‐qter. We have used a human liver cDNA probe in in situ hybridization experiments to metaphase chromosomes from two balanced translocation carriers, 46, XX, t(11;19) (q13;q13.1) and 46, XX, t(7;19) (q31.3;q13.3) to obtain a more precise localization. The results suggest a regional assignment for CYP1 to chromosome 19q13.1–13.3. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Regional localization of a human cytochrome P‐450 ( CYP1 ) to chromosome 19q 13.1–13.3

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References (4)

Publisher
Wiley
Copyright
Copyright © 1986 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1986.tb01044.x
Publisher site
See Article on Publisher Site

Abstract

Summary A phenobarbitone inducible cytochrome P‐450 gene family (CYP1) has recently been localized to chromosome 19q13.1‐qter. We have used a human liver cDNA probe in in situ hybridization experiments to metaphase chromosomes from two balanced translocation carriers, 46, XX, t(11;19) (q13;q13.1) and 46, XX, t(7;19) (q31.3;q13.3) to obtain a more precise localization. The results suggest a regional assignment for CYP1 to chromosome 19q13.1–13.3.

Journal

Annals of Human Genetics – Wiley

Published: Jul 1, 1986

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