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- Publisher
- Wiley
- Copyright
- Copyright © 1998 Wiley Subscription Services, Inc., A Wiley Company
- ISSN
- 0905-6157
- eISSN
- 1399-3038
- DOI
- 10.1111/j.1399-3038.1998.tb00358.x
- Publisher site
- See Article on Publisher Site
Abstract
Plasma levels of cAMP and serum concentrations of IgE have been determined in children with acute atopic dermatitis (AD) and in a healthy control group, to illuminate the pathophysiological mechanisms that cause AD. There were significantly lower plasma levels of cAMP (P < 0,001) and significantly higher levels of serum IgE (P < 0.004) in children with AD, in comparison with a healthy control group. It is possible that defective control of c‐AMP levels could contribute to the immunopathogenesis of AD and monitoring levels may be of value in the clinical evaluation of the disease.
Journal
Pediatric Allergy and Immunology – Wiley
Published: Aug 1, 1998