Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Radiation mucositis: a new approach to prevention and treatment

Radiation mucositis: a new approach to prevention and treatment Mucosal reactions in patients receiving radiation treatment for head and neck cancer are regarded as unavoidable side‐effects. The degree of mucositis experienced is determined by the treatment dose, radiation field size and fractionation schedules prescribed for individual patients. This article reviews a double‐blind placebo‐controlled trial of an antibiotic pastille which was aimed at reducing the more extreme effects of radiation mucositis. It identifies the role of oral care and hygiene, oral assessment and nursing support within a clinical trial setting. The results showed that the active pastille had a beneficial effect on the degree of mucositis experienced. Patients had a reduction in their weight loss in the active arm of the trial and the amount of yeast bacteria present in the oral cavity of those patients also diminished. It is worth noting that those patients in the placebo arm of the trial received both physical and psychological support from the nursing staff which may not have been available as frequently if they had not been in the trial. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Cancer Care Wiley

Radiation mucositis: a new approach to prevention and treatment

European Journal of Cancer Care , Volume 5 (3) – Sep 1, 1996

Loading next page...
 
/lp/wiley/radiation-mucositis-a-new-approach-to-prevention-and-treatment-PtaKM1qbEQ

References (55)

Publisher
Wiley
Copyright
Copyright © 1996 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0961-5423
eISSN
1365-2354
DOI
10.1111/j.1365-2354.1996.tb00227.x
Publisher site
See Article on Publisher Site

Abstract

Mucosal reactions in patients receiving radiation treatment for head and neck cancer are regarded as unavoidable side‐effects. The degree of mucositis experienced is determined by the treatment dose, radiation field size and fractionation schedules prescribed for individual patients. This article reviews a double‐blind placebo‐controlled trial of an antibiotic pastille which was aimed at reducing the more extreme effects of radiation mucositis. It identifies the role of oral care and hygiene, oral assessment and nursing support within a clinical trial setting. The results showed that the active pastille had a beneficial effect on the degree of mucositis experienced. Patients had a reduction in their weight loss in the active arm of the trial and the amount of yeast bacteria present in the oral cavity of those patients also diminished. It is worth noting that those patients in the placebo arm of the trial received both physical and psychological support from the nursing staff which may not have been available as frequently if they had not been in the trial.

Journal

European Journal of Cancer CareWiley

Published: Sep 1, 1996

There are no references for this article.