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Quality of life in metastatic breast cancer patients under chemotherapy or supportive care: a single‐institution comparative study

Quality of life in metastatic breast cancer patients under chemotherapy or supportive care: a... The aim of the present study was to evaluate quality of life (QoL) parameters in patients with metastatic breast cancer (MBC) and assess the potential differences between patients receiving chemotherapy and those undergoing supportive care interventions. In total, 210 women with MBC were enrolled in this prospective, randomized, single‐institution study. The primary outcome of the trial was QoL assessment, using the self‐administered European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ‐C30, version 3) and Quality of Life Questionnaire Breast 23 (QLQ‐BR23) questionnaires. Quality of life was found to be statistically better (P = 0.008) in MBC patients receiving chemotherapy than those under only supportive care. Statistically significant differences in favour of chemotherapy were also found in functioning subscales, symptom single‐item questions and sexual functioning. Our findings suggest that chemotherapy in MBC patients with good performance status is the more rational therapeutic approach in terms of QoL improvement. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Cancer Care Wiley

Quality of life in metastatic breast cancer patients under chemotherapy or supportive care: a single‐institution comparative study

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References (23)

Publisher
Wiley
Copyright
Copyright © 2007 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0961-5423
eISSN
1365-2354
DOI
10.1111/j.1365-2354.2006.00771.x
pmid
17760930
Publisher site
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Abstract

The aim of the present study was to evaluate quality of life (QoL) parameters in patients with metastatic breast cancer (MBC) and assess the potential differences between patients receiving chemotherapy and those undergoing supportive care interventions. In total, 210 women with MBC were enrolled in this prospective, randomized, single‐institution study. The primary outcome of the trial was QoL assessment, using the self‐administered European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ‐C30, version 3) and Quality of Life Questionnaire Breast 23 (QLQ‐BR23) questionnaires. Quality of life was found to be statistically better (P = 0.008) in MBC patients receiving chemotherapy than those under only supportive care. Statistically significant differences in favour of chemotherapy were also found in functioning subscales, symptom single‐item questions and sexual functioning. Our findings suggest that chemotherapy in MBC patients with good performance status is the more rational therapeutic approach in terms of QoL improvement.

Journal

European Journal of Cancer Care – Wiley

Published: Sep 1, 2007

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