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Probable assignment of the locus determining human red cell acid phosphatase ACP 1 to chromosome 2 using somatic cell hybrids

Probable assignment of the locus determining human red cell acid phosphatase ACP 1 to chromosome... SUMMARY Twelve independent interspecific hybrid lines, from six different crosses, together with nine subclones, were tested for the presence of the human enzymes ACP1, MOR‐S and ICD‐S. The hybrids were also tested for a total of 27 other human enzymes. With one exception the data were consistent with the synteny of ACP1, MOR‐S and ICD‐S. Detailed chromosome analysis of the subclones confirmed the assignment of these loci to chromosome 2. In the remaining hybrid chromosome 2 was present, together with MOR‐S and ICD‐S but ACP1 was not seen. Possible explanations for this discrepancy are discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Probable assignment of the locus determining human red cell acid phosphatase ACP 1 to chromosome 2 using somatic cell hybrids

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References (23)

Publisher
Wiley
Copyright
Copyright © 1974 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1974.tb01987.x
Publisher site
See Article on Publisher Site

Abstract

SUMMARY Twelve independent interspecific hybrid lines, from six different crosses, together with nine subclones, were tested for the presence of the human enzymes ACP1, MOR‐S and ICD‐S. The hybrids were also tested for a total of 27 other human enzymes. With one exception the data were consistent with the synteny of ACP1, MOR‐S and ICD‐S. Detailed chromosome analysis of the subclones confirmed the assignment of these loci to chromosome 2. In the remaining hybrid chromosome 2 was present, together with MOR‐S and ICD‐S but ACP1 was not seen. Possible explanations for this discrepancy are discussed.

Journal

Annals of Human GeneticsWiley

Published: Jul 1, 1974

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