Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/wiley/peptides-as-key-components-in-the-design-of-non-viral-vectors-for-gene-saPEiHBVpS
References (95)
-
N. Baumhover, J. Duskey, S. Khargharia, Christopher White, S. Crowley, Rondine Allen, K. Rice (2015)
Structure-Activity Relationship of PEGylated Polylysine Peptides as Scavenger Receptor Inhibitors for Non-Viral Gene Delivery.Molecular pharmaceutics, 12 12
-
K. Ezzat, S. Andaloussi, E. Zaghloul, Taavi Lehto, Staffan Lindberg, Pedro Moreno, Joana Viola, T. Magdy, R. Abdo, P. Guterstam, R. Sillard, S. Hammond, Matthew Wood, A. Arzumanov, M. Gait, C. Smith, M. Hällbrink, Ü. Langel (2011)
PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulationNucleic Acids Research, 39
-
D. Oupický, A. Parker, L. Seymour (2002)
Laterally stabilized complexes of DNA with linear reducible polycations: strategy for triggered intracellular activation of DNA delivery vectors.Journal of the American Chemical Society, 124 1
-
Huihui Kuang, Sook Ku, E. Kokkoli (2017)
The design of peptide‐amphiphiles as functional ligands for liposomal anticancer drug and gene deliveryAdvanced Drug Delivery Reviews, 110‐111
-
Jisang Yoo, DaeYong Lee, V. Gujrati, Sanoj Rejinold, Kamali Lekshmi, Saji Uthaman, Chanuk Jeong, I. Park, S. Jon, Yeu‐Chun Kim (2017)
Bioreducible branched poly(modified nona‐arginine) cell‐penetrating peptide as a novel gene delivery platformJournal of Controlled Release, 246
-
Yilong Cheng, Roma Yumul, S. Pun (2016)
Virus-Inspired Polymer for Efficient In Vitro and In Vivo Gene Delivery.Angewandte Chemie, 55 39
-
O. Veiseh, Forrest Kievit, Vick Liu, Chen Fang, Zachary Stephen, R. Ellenbogen, Miqin Zhang (2013)
In vivo safety evaluation of polyarginine coated magnetic nanovectors.Molecular pharmaceutics, 10 11
-
Nirav Khatri, Dipesh Baradia, I. Vhora, Mohan Rathi, A. Misra (2014)
Development and Characterization of siRNA Lipoplexes: Effect of Different Lipids, In Vitro Evaluation in Cancerous Cell Lines and In Vivo Toxicity StudyAAPS PharmSciTech, 15
-
A. Oryan, Esmat Alemzadeh, M. Zarei (2019)
Basic concepts, current evidence, and future potential for gene therapy in managing cutaneous woundsBiotechnology Letters, 41
-
Young-Wook Won, Kyung-Min Kim, S. An, Minhyung Lee, Y. Ha, Yong-Hee Kim (2011)
Suicide gene therapy using reducible poly (oligo-D-arginine) for the treatment of spinal cord tumors.Biomaterials, 32 36
-
Amanda Dodd, Dirk Swanevelder, Nerve Zhou, D. Brady, J. Hallsworth, K. Rumbold (2018)
Streptomyces albulus yields ε-poly-l-lysine and other products from salt-contaminated glycerol wasteJournal of Industrial Microbiology & Biotechnology, 45
-
Xiaofei Liang, B. Shi, Kai Wang, Mingliang Fan, Dejin Jiao, J. Ao, Na Song, Chun Wang, J. Gu, Zonghai Li (2016)
Development of self-assembling peptide nanovesicle with bilayers for enhanced EGFR-targeted drug and gene delivery.Biomaterials, 82
-
Y. Wan, P. Moyle, M. Christie, I. Toth (2016)
Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity.Nanomedicine, 11 8
-
L. Hyndman, J. Lemoine, Leaf Huang, D. Porteous, A. Boyd, X. Nan (2004)
HIV-1 Tat protein transduction domain peptide facilitates gene transfer in combination with cationic liposomes.Journal of controlled release : official journal of the Controlled Release Society, 99 3
-
E. Urgard, Aleksei Brjalin, Ü. Langel, M. Pooga, A. Rebane, T. Annilo (2017)
Comparison of Peptide- and Lipid-Based Delivery of miR-34a-5p Mimic into PPC-1 Cells.Nucleic acid therapeutics, 27 5
-
C. Barnes, Olivia Scheideler, D. Schaffer (2019)
Engineering the AAV capsid to evade immune responses.Current opinion in biotechnology, 60
-
Ching-Yao Yang, P. Renfrew, Andrew Olsen, Michelle Zhang, Carlo Yuvienco, Richard Bonneau, J. Montclare (2014)
Improved Stability and Half‐Life of Fluorinated Phosphotriesterase Using RosettaChemBioChem, 15
-
Julia Suhorutšenko, N. Oskolkov, Piret Arukuusk, K. Kurrikoff, E. Eriste, D. Copolovici, Ű. Langel (2011)
Cell-penetrating peptides, PepFects, show no evidence of toxicity and immunogenicity in vitro and in vivo.Bioconjugate chemistry, 22 11
-
D. Walsh, Robert Murphy, A. Panarella, R. Raftery, B. Cavanagh, J. Simpson, F. O'Brien, A. Heise, S. Cryan (2018)
Bioinspired Star-Shaped Poly(l-lysine) Polypeptides: Efficient Polymeric Nanocarriers for the Delivery of DNA to Mesenchymal Stem Cells.Molecular pharmaceutics, 15 5
-
Rong-Feng Shi, Weishuai Lian, Shilong Han, Chuanwu Cao, Yin‐peng Jin, Y. Yuan, Hui Zhao, Maoquan Li (2018)
Nanosphere-mediated co-delivery of VEGF-A and PDGF-B genes for accelerating diabetic foot ulcers healing in ratsGene Therapy, 25
-
C. Byon, J. Heath, Yabing Chen (2016)
Redox signaling in cardiovascular pathophysiology: A focus on hydrogen peroxide and vascular smooth muscle cellsRedox Biology, 9
-
Yu Wei, Ying Ji, Linlin Xiao, Quan-kui Lin, Jian-ping Xu, Ke‐feng Ren, J. Ji (2013)
Surface engineering of cardiovascular stent with endothelial cell selectivity for in vivo re-endothelialisation.Biomaterials, 34 11
-
Paolo Saccardo, A. Villaverde, Nuria González-Montalbán (2009)
Peptide-mediated DNA condensation for non-viral gene therapy.Biotechnology advances, 27 4
-
Albert Kwok, D. McCarthy, S. Hart, A. Tagalakis (2016)
Systematic Comparisons of Formulations of Linear Oligolysine Peptides with siRNA and Plasmid DNAChemical Biology & Drug Design, 87
-
C. Zambaldo, Xiaozhou Luo, Angad Mehta, P. Schultz (2017)
Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino Acids.Journal of the American Chemical Society, 139 34
-
D. Phillips, M. Gibson (2012)
Biodegradable poly(disulfide)s derived from RAFT polymerization: monomer scope, glutathione degradation, and tunable thermal responses.Biomacromolecules, 13 10
-
Young-Wook Won, Hyun Kim, Minhyung Lee, Yong-Hee Kim (2010)
Reducible poly(oligo-D-arginine) for enhanced gene expression in mouse lung by intratracheal injection.Molecular therapy : the journal of the American Society of Gene Therapy, 18 4
-
Ji Kang, G. Battogtokh, Y. Ko (2017)
Self-Assembling Lipid-Peptide Hybrid Nanoparticles of Phospholipid-Nonaarginine Conjugates for Enhanced Delivery of Nucleic Acid Therapeutics.Biomacromolecules, 18 11
-
Xuefang Hao, Qian Li, Juan Lv, Li Yu, Xiang-kui Ren, Li Zhang, Yakai Feng, Wencheng Zhang (2015)
CREDVW-Linked Polymeric Micelles As a Targeting Gene Transfer Vector for Selective Transfection and Proliferation of Endothelial Cells.ACS applied materials & interfaces, 7 22
-
E. Alinejad-Mofrad, B. Malaekeh-Nikouei, Leila Gholami, Seyed Mousavi, H. Sadeghnia, Mohammad Mohajeri, Majid Darroudi, R. Oskuee (2019)
Evaluation and comparison of cytotoxicity, genotoxicity, and apoptotic effects of poly-l-lysine/plasmid DNA micro- and nanoparticlesHuman & Experimental Toxicology, 38
-
Alexander Eldredge, Mark Johnson, Nathan Oldenhuis, Z. Guan (2016)
Focused Library Approach to Discover Discrete Dipeptide Bolaamphiphiles for siRNA Delivery.Biomacromolecules, 17 10
-
Piul Rabbani, Anna Zhou, Zachary Borab, Joseph Frezzo, Nikita Srivastava, H. More, William Rifkin, Joshua David, Samuel Berens, Raymond Chen, Sophia Hameedi, M. Junejo, Camille Kim, Rita Sartor, C. Liu, P. Saadeh, J. Montclare, Daniel Ceradini (2017)
Novel lipoproteoplex delivers Keap1 siRNA based gene therapy to accelerate diabetic wound healing.Biomaterials, 132
-
Sarah Erickson, Raja Mukherjee, Rachel Kelemen, C. Wrobel, Xiaofu Cao, A. Chatterjee (2017)
Precise Photoremovable Perturbation of a Virus-Host Interaction.Angewandte Chemie, 56 15
-
S. Yamano, C. Viet, D. Dang, Jisen Dai, S. Hanatani, T. Takayama, Hironori Kasai, K. Imamura, Ronald Campbell, Y. Ye, J. Dolan, William Kwon, Stefan Schneider, B. Schmidt (2017)
Ex vivo nonviral gene delivery of &mgr;-opioid receptor to attenuate cancer-induced painPAIN, 158
-
Jongsu Woo, Seongho Bae, Bok-Deuk Kim, Jin Park, Subin Jung, Minhyung Lee, Yong-Hee Kim, D. Choi (2015)
Cardiac Usage of Reducible Poly(oligo-D-arginine) As a Gene Carrier for Vascular Endothelial Growth Factor ExpressionPLoS ONE, 10
-
Y. Chen, Megan Keiser, B. Davidson (2018)
Viral Vectors for Gene TransferCurrent Protocols in Mouse Biology, 8
-
R. Jenkins, S. Herrick, Qing‐Hai Meng, C. Kinnon, G. Laurent, R. McAnulty, S. Hart (2000)
An integrin-targeted non-viral vector for pulmonary gene therapyGene Therapy, 7
-
Haimanti Mandal, S. Katiyar, R. Swami, Varun Kushwah, Parmeshwar Katare, A. Meka, S. Banerjee, A. Popat, Sanyog Jain (2018)
&egr;‐Poly‐L‐Lysine/plasmid DNA nanoplexes for efficient gene delivery in vivoInternational Journal of Pharmaceutics, 542
-
S. Al-Taei, Neal Penning, J. Simpson, S. Futaki, T. Takeuchi, I. Nakase, A. Jones (2006)
Intracellular traffic and fate of protein transduction domains HIV-1 TAT peptide and octaarginine. Implications for their utilization as drug delivery vectors.Bioconjugate chemistry, 17 1
-
Chang Liu, Kuan Jiang, Lingyu Tai, Yu Liu, G. Wei, Weiyue Lu, W. Pan (2016)
Facile Noninvasive Retinal Gene Delivery Enabled by Penetratin.ACS applied materials & interfaces, 8 30
-
Sonali Fonseca, Mark Pereira, S. Kelley (2009)
Recent advances in the use of cell-penetrating peptides for medical and biological applications.Advanced drug delivery reviews, 61 11
-
Min Shim, Younan Xia (2013)
A reactive oxygen species (ROS)-responsive polymer for safe, efficient, and targeted gene delivery in cancer cells.Angewandte Chemie, 52 27
-
Hongtao Lv, Shubiao Zhang, B. Wang, S. Cui, Jie Yan (2006)
Toxicity of cationic lipids and cationic polymers in gene delivery.Journal of controlled release : official journal of the Controlled Release Society, 114 1
-
Maren Thomas, Kerstin Lange‐Grünweller, Eyas Dayyoub, U. Bakowsky, U. Weirauch, A. Aigner, R. Hartmann, A. Grünweller (2012)
PEI-complexed LNA antiseeds as miRNA inhibitorsRNA Biology, 9
-
M. Bartneck, K. Heffels, Yu Pan, M. Bovi, G. Zwadlo‐Klarwasser, J. Groll (2012)
Inducing healing-like human primary macrophage phenotypes by 3D hydrogel coated nanofibres.Biomaterials, 33 16
-
Yu Wei, Ying Ji, Linlin Xiao, Quankui Lin, J. Ji (2011)
Different complex surfaces of polyethyleneglycol (PEG) and REDV ligand to enhance the endothelial cells selectivity over smooth muscle cells.Colloids and surfaces. B, Biointerfaces, 84 2
-
M. Byrne, D. Victory, A. Hibbitts, M. Lanigan, A. Heise, S. Cryan (2013)
Molecular weight and architectural dependence of well-defined star-shaped poly(lysine) as a gene delivery vector.Biomaterials science, 1 12
-
Rebecca Taylor, M. Zahid (2020)
Cell Penetrating Peptides, Novel Vectors for Gene TherapyPharmaceutics, 12
-
M. Golan, Valeria Feinshtein, A. David (2016)
Conjugates of HA2 with octaarginine-grafted HPMA copolymer offer effective siRNA delivery and gene silencing in cancer cells.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 109
-
Pengfei Zhang, B. Shi, Huiping Gao, Hua Jiang, J. Kong, Jin Yan, Xiaorong Pan, Kesang Li, Pengwei Zhang, M. Yao, Shengli Yang, J. Gu, Hongyang Wang, Zonghai Li (2014)
An EpCAM/CD3 bispecific antibody efficiently eliminates hepatocellular carcinoma cells with limited galectin-1 expressionCancer Immunology, Immunotherapy, 63
-
Amir Varkouhi, M. Scholte, G. Storm, H. Haisma (2011)
Endosomal escape pathways for delivery of biologicals.Journal of controlled release : official journal of the Controlled Release Society, 151 3
-
Alfredo Erazo-Oliveras, Nandhini Muthukrishnan, Ryan Baker, Ting-Yi Wang, J. Pellois (2012)
Improving the Endosomal Escape of Cell-Penetrating Peptides and Their Cargos: Strategies and ChallengesPharmaceuticals, 5
-
Eun‐Kyoung Bang, Hanna Cho, S. Jeon, Na Tran, Dong-Kwon Lim, W. Hur, Taebo Sim (2018)
Amphiphilic small peptides for delivery of plasmid DNAs and siRNAsChemical Biology & Drug Design, 91
-
Mania Dorrani, O. Garbuzenko, T. Minko, B. Michniak-Kohn (2016)
Development of edge-activated liposomes for siRNA delivery to human basal epidermis for melanoma therapy.Journal of controlled release : official journal of the Controlled Release Society, 228
-
H. Hermeking (2010)
The miR-34 family in cancer and apoptosisCell Death and Differentiation, 17
-
Yujia Huang, T. Liu (2018)
Therapeutic applications of genetic code expansionSynthetic and Systems Biotechnology, 3
-
Youyong Yuan, Chong-Jing Zhang, B. Liu (2015)
A Photoactivatable AIE Polymer for Light-Controlled Gene Delivery: Concurrent Endo/Lysosomal Escape and DNA Unpacking.Angewandte Chemie, 54 39
-
Can Liu, K. Kelnar, Bigang Liu, Xin Chen, Tammy Calhoun‐Davis, Hangwen Li, Lubna Patrawala, Hong Yan, Collene Jeter, S. Honorio, J. Wiggins, A. Bader, R. Fagin, D. Brown, D. Tang (2010)
Identification of miR-34a as a potent inhibitor of prostate cancer progenitor cells and metastasis by directly repressing CD44Nature medicine, 17
-
Hua Jiang, Qiongna Dong, Xiaoying Luo, B. Shi, Huamao Wang, Huiping Gao, J. Kong, Jiqin Zhang, Zonghai Li (2014)
The monoclonal antibody CH12 augments 5-fluorouracil-induced growth suppression of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III.Cancer letters, 342 1
-
I. Ruseska, A. Zimmer (2020)
Internalization mechanisms of cell-penetrating peptidesBeilstein Journal of Nanotechnology, 11
-
Xiaojun Cai, Chunyan Dong, Haiqing Dong, Gangmin Wang, G. Pauletti, Xiaojing Pan, Huiyun Wen, Isaac Mehl, Yongyong Li, Donglu Shi (2012)
Effective gene delivery using stimulus-responsive catiomer designed with redox-sensitive disulfide and acid-labile imine linkers.Biomacromolecules, 13 4
-
A. Malek, Olivia Merkel, L. Fink, F. Czubayko, T. Kissel, A. Aigner (2009)
In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes.Toxicology and applied pharmacology, 236 1
-
O. Boussif, F. Lezoualc’h, M. Zanta, M. Mergny, D. Scherman, B. Demeneix, J. Behr (1995)
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.Proceedings of the National Academy of Sciences of the United States of America, 92 16
-
Hyesun Hyun, Young-Wook Won, Kyung-Min Kim, Jiyoung Lee, Minhyung Lee, Yong-Hee Kim (2010)
Therapeutic effects of a reducible poly (oligo-D-arginine) carrier with the heme oxygenase-1 gene in the treatment of hypoxic-ischemic brain injury.Biomaterials, 31 34
-
Yifeng Lei, Lixue Tang, Yangzhouyun Xie, Yunlei Xianyu, Lingmin Zhang, Peng Wang, Yoh Hamada, Kai Jiang, Wenfu Zheng, Xingyu Jiang (2017)
Gold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancerNature Communications, 8
-
Julie Shi, Russell Johnson, Joan Schellinger, Peter Carlson, S. Pun (2012)
Reducible HPMA-co-oligolysine copolymers for nucleic acid delivery.International journal of pharmaceutics, 427 1
-
T. Pangburn, M. Petersen, Brett Waybrant, Maroof Adil, E. Kokkoli (2009)
Peptide- and aptamer-functionalized nanovectors for targeted delivery of therapeutics.Journal of biomechanical engineering, 131 7
-
H. More, Joseph Frezzo, Jisen Dai, S. Yamano, J. Montclare (2014)
Gene delivery from supercharged coiled-coil protein and cationic lipid hybrid complex.Biomaterials, 35 25
-
S. Yamano, Jisen Dai, Carlo Yuvienco, Sachin Khapli, A. Moursi, J. Montclare (2011)
Modified Tat peptide with cationic lipids enhances gene transfection efficiency via temperature-dependent and caveolae-mediated endocytosis.Journal of controlled release : official journal of the Controlled Release Society, 152 2
-
Janelle Salameh, Le Zhou, S. Ward, C. Chalarca, T. Emrick, M. Figueiredo (2019)
Polymer-mediated gene therapy: Recent advances and merging of delivery techniques.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
-
Jiyoung Lee, Hyesun Hyun, Jinyoung Kim, J. Ryu, Hyun Kim, J. Park, Minhyung Lee (2012)
Dexamethasone-loaded peptide micelles for delivery of the heme oxygenase-1 gene to ischemic brain.Journal of controlled release : official journal of the Controlled Release Society, 158 1
-
A. Pensado, F. Díaz-Corrales, B. Cerda, L. Valdés-Sánchez, Ana Boz, Daniel Rodriguez-Martinez, A. García-Delgado, B. Seijo, S. Bhattacharya, Alejandro Sanchez (2016)
Span poly-L-arginine nanoparticles are efficient non-viral vectors for PRPF31 gene delivery: An approach of gene therapy to treat retinitis pigmentosa.Nanomedicine : nanotechnology, biology, and medicine, 12 8
-
Chanuk Jeong, Jisang Yoo, DaeYong Lee, Yeu‐Chun Kim (2016)
A branched TAT cell-penetrating peptide as a novel delivery carrier for the efficient gene transfectionBiomaterials Research, 20
-
Devika Manickam, Harender Bisht, L. Wan, G. Mao, D. Oupický (2005)
Influence of TAT-peptide polymerization on properties and transfection activity of TAT/DNA polyplexes.Journal of controlled release : official journal of the Controlled Release Society, 102 1
-
Kai Han, Qi Lei, Hui-zhen Jia, Shibo Wang, Wei-Na Yin, Weihai Chen, Si-Xue Cheng, Xianzheng Zhang (2015)
A Tumor Targeted Chimeric Peptide for Synergistic Endosomal Escape and Therapy by Dual‐Stage Light ManipulationAdvanced Functional Materials, 25
-
J. Park, Hyun Kim, Jin Park, Minhyung Lee (2012)
Amphiphilic peptide carrier for the combined delivery of curcumin and plasmid DNA into the lungs.Biomaterials, 33 27
-
A. Parthasarathy, Sasikala Anandamma, Karunakaran Kalesh (2019)
The Medicinal Chemistry of Therapeutic Peptides: Recent Developments in Synthesis and Design Optimizations.Current medicinal chemistry
-
Pieter Smith, J. Brender, U. Dürr, Jiadi Xu, D. Mullen, M. Holl, A. Ramamoorthy (2010)
Solid-state NMR reveals the hydrophobic-core location of poly(amidoamine) dendrimers in biomembranes.Journal of the American Chemical Society, 132 23
-
R. Kircheis, L. Wightman, A. Schreiber, B. Robitza, Vanessa Rössler, M. Kursa, E. Wagner (2001)
Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic applicationGene Therapy, 8
-
George Wu, Catherine Wu (1988)
Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro.Biochemistry, 27 3
-
Lingyu Tai, Chang Liu, Kuan Jiang, Xishan Chen, G. Wei, Weiyue Lu, W. Pan (2017)
Noninvasive delivery of oligonucleotide by penetratin-modified polyplexes to inhibit protein expression of intraocular tumor.Nanomedicine : nanotechnology, biology, and medicine, 13 6
-
Z. Taimeh, J. Loughran, E. Birks, R. Bolli (2013)
Vascular endothelial growth factor in heart failureNature Reviews Cardiology, 10
-
Reena Goswami, Gayatri Subramanian, L. Silayeva, Isabelle Newkirk, D. Doctor, Karan Chawla, S. Chattopadhyay, D. Chandra, N. Chilukuri, Venkaiah Betapudi (2019)
Gene Therapy Leaves a Vicious CycleFrontiers in Oncology, 9
-
Egle-Helene Ervin, M. Pook, Indrek Teino, Valmar Kasuk, Annika Trei, M. Pooga, T. Maimets (2019)
Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14Stem Cell Research & Therapy, 10
-
J. Campbell, T. McFarland, J. Stout (2016)
Ocular Gene Therapy.Developments in ophthalmology, 55
-
Piret Arukuusk, Ly Pärnaste, M. Hällbrink, Ü. Langel (2015)
PepFects and NickFects for the Intracellular Delivery of Nucleic Acids.Methods in molecular biology, 1324
-
D. Copolovici, K. Langel, E. Eriste, Ü. Langel (2014)
Cell-penetrating peptides: design, synthesis, and applications.ACS nano, 8 3
-
Daniel Holycross, M. Chai (2013)
Comprehensive NMR Studies of the Structures and Properties of PEI PolymersMacromolecules, 46
-
A. Macho, M. Calzado, Luis Jiménez-Reina, Eva Ceballos, Javier León, Eduardo Muñoz (1999)
Susceptibility of HIV-1-TAT transfected cells to undergo apoptosis. Biochemical mechanismsOncogene, 18
-
Ji-Sing Liou, B. Liu, Adam Martin, Yue-Wern Huang, H. Chiang, Han-Jung Lee (2012)
Protein transduction in human cells is enhanced by cell-penetrating peptides fused with an endosomolytic HA2 sequencePeptides, 37
-
I. Zuhorn, J. Engberts, D. Hoekstra (2007)
Gene delivery by cationic lipid vectors: overcoming cellular barriersEuropean Biophysics Journal, 36
-
Michael Riley, W. Vermerris (2017)
Recent Advances in Nanomaterials for Gene Delivery—A ReviewNanomaterials, 7
-
L. Avila, L. Avila, L. Aps, N. Ploscariu, Pinakin Sukthankar, Pinakin Sukthankar, R. Guo, K. Wilkinson, Patrícia Games, R. Szoszkiewicz, Rúbens Alves, Mariana Diniz, Y. Fang, L. Ferreira, J. Tomich (2016)
Gene delivery and immunomodulatory effects of plasmid DNA associated with Branched Amphiphilic Peptide Capsules.Journal of controlled release : official journal of the Controlled Release Society, 241
-
Runhui Liu, Xinyu Chen, S. Gellman, K. Masters (2013)
Nylon-3 polymers that enable selective culture of endothelial cells.Journal of the American Chemical Society, 135 44
-
Xiao-chao Chen, Jing Chen, Rong Fu, P. Rao, R. Weller, J. Bradshaw, Shutao Liu (2017)
Can the Cellular Internalization of Cargo Proteins Be Enhanced by Fusing a Tat Peptide in the Center of Proteins? A Fluorescence Study.Journal of pharmaceutical sciences, 107 3
- Publisher
- Wiley
- Copyright
- © 2021 Wiley Periodicals LLC.
- eISSN
- 2475-8817
- DOI
- 10.1002/pep2.24189
- Publisher site
- See Article on Publisher Site
Abstract
Successful clinical implementation of gene delivery relies on the use of viral or non‐viral based vectors to package and protect the therapeutic nucleic acid. These vehicles must also be able to direct the fate of the cargo once it has entered the cell to ensure that the nucleic acid is functional, and the desired outcome is achieved. Compared to viral vectors, non‐viral vectors have the advantage of incorporating different material types such as lipids, polymers, and peptides to tune overall safety and efficacy. Peptides are especially powerful when used in gene delivery vectors as they are able to increase gene delivery efficacy by introducing new biochemical functionality. This review will discuss the use of peptides as central design components in non‐viral gene delivery vectors. The contribution of the peptide component to the overall functionality of the delivery vehicle will be highlighted, with a focus on peptides as the only vehicle component or peptides in complex assemblies with lipids or polymers.
Journal
Peptide Science – Wiley
Published: Mar 1, 2021
Keywords: ; ; ; ;