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Pd‐Catalyzed Ortho‐Directed C—H Glycosylation of Arenes Using N‐linked Bidentate Auxiliaries

Pd‐Catalyzed Ortho‐Directed C—H Glycosylation of Arenes Using N‐linked Bidentate Auxiliaries A set of Pd‐catalyzed ortho‐directed C—H glycosylation reactions with glycosyl chloride donors using various N‐linked bidentate auxiliaries has been developed for synthesis of C‐aryl glycosides. A broad range of pyranose and furanose moieties can be installed on the ortho position of arylamine, carbazole, indole and benzylamine type substrates in high yield and with high regio‐ and diastereoselectivity. These auxiliaries can be readily installed and removed under relatively mild conditions. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chinese Journal of Chemistry Wiley

Pd‐Catalyzed Ortho‐Directed C—H Glycosylation of Arenes Using N‐linked Bidentate Auxiliaries

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References (8)

Publisher
Wiley
Copyright
© 2021 SIOC, CAS, Shanghai, & WILEY‐VCH GmbH
ISSN
1001-604X
eISSN
1614-7065
DOI
10.1002/cjoc.202000500
Publisher site
See Article on Publisher Site

Abstract

A set of Pd‐catalyzed ortho‐directed C—H glycosylation reactions with glycosyl chloride donors using various N‐linked bidentate auxiliaries has been developed for synthesis of C‐aryl glycosides. A broad range of pyranose and furanose moieties can be installed on the ortho position of arylamine, carbazole, indole and benzylamine type substrates in high yield and with high regio‐ and diastereoselectivity. These auxiliaries can be readily installed and removed under relatively mild conditions.

Journal

Chinese Journal of ChemistryWiley

Published: Mar 1, 2021

Keywords: ; ; ; ;

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