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Jassim Suwaidi, P. Berger, D. Holmes (2000)
Coronary artery stents.JAMA, 284 14
Oesterle Oesterle (1999)
Percutaneous myocardial revascularization: Initial results from the roll‐in phase of the PACIFIC trial (abstract)J Am Coll Cardiol, 82
(2001)
Blinded evaluation of laser (PTMR) intervention electively for angina pectoris (abstract)
J. Spertus, Jennifer Winder, T. Dewhurst, R. Deyo, J. Prodzinski, M. Mcdonnell, S. Fihn (1995)
Development and evaluation of the Seattle Angina Questionnaire: a new functional status measure for coronary artery disease.Journal of the American College of Cardiology, 25 2
P. Serruys, Felix Unger, J. Sousa, Adib Jatene, H. Bonnier, Jacques Schönberger, N. Buller, Robert Bonser, M. brand, L. Herwerden, M. Morel, Ben Hout (2001)
Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease.The New England journal of medicine, 344 15
Oesterle Oesterle, Sanborn Sanborn, Ali Ali (2000)
Percutaneous transmyocardial laser revascularisation for severe angina: The PACIFIC randomised trial. Potential class improvement from intramyocardial channelsLancet, 356
S. Oesterle, T. Sanborn, N. Ali, J. Resar, S. Ramee, R. Heuser, L. Dean, W. Knopf, P. Schofield, G. Schaer, G. Reeder, R. Masden, A. Yeung, D. Burkhoff (2000)
Percutaneous transmyocardial laser revascularisation for severe angina: the PACIFIC randomised trialThe Lancet, 356
D. Maron (2000)
Percutaneous coronary intervention versus medical therapy for coronary heart diseaseCurrent Atherosclerosis Reports, 2
E. Topol, F. Leya, C. Pinkerton, P. Whitlow, B. Höfling, C. Simonton, R. Masden, P. Serruys, M. Leon, David Williams, S. King, D. Mark, J. Isner, D. Holmes, Stephen Ellis, Kerry Lee, G. Keeler, L. Berdan, T. Hinohara, R. Califf (1993)
A Comparison of Directional Atherectomy with Coronary Angioplasty in Patients with Coronary Artery DiseaseThe New England Journal of Medicine, 329
RITA-2 participants (1993)
Coronary angioplasty versus coronary artery bypass surgery: the Randomised Intervention Treatment of Angina (RITA) trialThe Lancet, 341
Topol Topol, Leya Leya, Pinkerton Pinkerton (1993)
A comparison of directional atherectomy with coronary angioplasty in patients with coronary artery disease. The CAVEAT Study GroupN Engl J Med, 329
D. Mukherjee, Deepak Bhatt, M. Roe, V. Patel, S. Ellis (1999)
Direct myocardial revascularization and angiogenesis--how many patients might be eligible?The American journal of cardiology, 84 5
(1997)
Five-year clinical and functional outcome comparing bypass surgery and angioplasty in patients with multivessel coronary disease. A multicenter randomized trial. Writing Group for the Bypass Angioplasty Revascularization Investigation (BARI) Investigators.JAMA, 277 9
Whitbourn, Oesterle (1999)
Percutaneous Myocardial Revascularization.Current interventional cardiology reports, 1 2
(2004)
Final results of the DIRECT Trial (abstract). ACC 50th Annual Scientific Sessions Late-Breaking Clinical Trials
Objectives: The present study assesses clinical outcomes in patients from the Potential Angina Class Improvement From Intramyocardial Channels (PACIFIC) trial of percutaneous transmyocardial revascularization (PTMR) who had previously been considered “no‐option,” but who subsequently underwent percutaneous coronary intervention (PCI) for continuing symptoms. Background: Patients with advanced symptomatic coronary artery disease who are not candidates for coronary artery bypass grafting (CABG) or PCI comprise an important group, for which no established treatment is currently available. These patients have been described as having “no option,” and are currently targeted for various experimental therapies. One such proposed therapy, PTMR, was recently examined in the PACIFIC trial. A subgroup of patients in this trial subsequently underwent PCI, although to initially qualify for the study they had previously been considered as unsuitable for PCI and as having “no option.” The therapeutic benefit of PCI for patients of this type is unknown. Methods: A retrospective analysis was performed on data obtained from all subjects of the PACIFIC study who underwent PCI within the 12‐month follow‐up period. Results: Ten subjects originally randomized to PTMR and 11 subjects from the medical treatment group underwent PCI. Most had undergone at least one prior PCI and at least one CABG, and there was a high prevalence of cardiovascular risk factors. Despite excellent immediate procedural success, PCI resulted in only modest, statistically nonsignificant increases in mean exercise duration, small improvements in angina status, and no significant improvements in quality of life. Conclusions: These data suggest that PCI provides only marginal—if any—symptomatic benefit in these patients. (J Interven Cardiol 2004;17:87–91)
Journal of Interventional Cardiology – Wiley
Published: Apr 1, 2004
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