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Obesity paradox at patients with chronic and acute coronary artery disease: A letter to the editor

Obesity paradox at patients with chronic and acute coronary artery disease: A letter to the editor Dear Editor,The study of Morishita et al. investigated relationships between body mass index (BMI) and clinical outcomes following percutaneous coronary intervention (PCI) in patients with chronic coronary artery disease (CAD).1 They reviewed 1104 subjects who underwent PCI between 2006 and 2015, and divided them by BMI into three groups: lean (<18.5 kg/m2), normal (18.5–24.9 kg/m2) and overweight/obese (≥25 kg/m2). The primary endpoint was all‐cause mortality, and the secondary endpoint was 3‐point major adverse cardiovascular events (MACE). The authors found lean category was associated with adverse outcomes among CAD patients. An obesity paradox regarding the independent association of elevated BMI with reduced mortality after PCI is evident in both males and females.Their interesting findings are consistent with the results of our prospective studies about the influence of metabolic syndrome (MetS) and various obesity indices on clinical severity and prognosis of acute ST‐elevation myocardial infarction (STEMI) treated with primary PCI.2,3 We found that MetS increased the risk of >1 significantly stenosed coronary arteries (CAs), visceral obesity increased the risk of dyspnoea (Body adiposity index, BAI), total in‐hospital complications (Conicity index, C index), significant proximal/middle coronary segments stenosis and Gensini score ≥20 (waist‐to‐hip ratio, WHR), and of heart failure (waist‐to‐height ratio, WHtR), while overall obesity http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Clinical Investigation Wiley

Obesity paradox at patients with chronic and acute coronary artery disease: A letter to the editor

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References (7)

Publisher
Wiley
Copyright
Copyright © 2022 Stichting European Society for Clinical Investigation Journal Foundation
ISSN
0014-2972
eISSN
1365-2362
DOI
10.1111/eci.13810
Publisher site
See Article on Publisher Site

Abstract

Dear Editor,The study of Morishita et al. investigated relationships between body mass index (BMI) and clinical outcomes following percutaneous coronary intervention (PCI) in patients with chronic coronary artery disease (CAD).1 They reviewed 1104 subjects who underwent PCI between 2006 and 2015, and divided them by BMI into three groups: lean (<18.5 kg/m2), normal (18.5–24.9 kg/m2) and overweight/obese (≥25 kg/m2). The primary endpoint was all‐cause mortality, and the secondary endpoint was 3‐point major adverse cardiovascular events (MACE). The authors found lean category was associated with adverse outcomes among CAD patients. An obesity paradox regarding the independent association of elevated BMI with reduced mortality after PCI is evident in both males and females.Their interesting findings are consistent with the results of our prospective studies about the influence of metabolic syndrome (MetS) and various obesity indices on clinical severity and prognosis of acute ST‐elevation myocardial infarction (STEMI) treated with primary PCI.2,3 We found that MetS increased the risk of >1 significantly stenosed coronary arteries (CAs), visceral obesity increased the risk of dyspnoea (Body adiposity index, BAI), total in‐hospital complications (Conicity index, C index), significant proximal/middle coronary segments stenosis and Gensini score ≥20 (waist‐to‐hip ratio, WHR), and of heart failure (waist‐to‐height ratio, WHtR), while overall obesity

Journal

European Journal of Clinical InvestigationWiley

Published: Aug 1, 2022

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