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A NOTE ON T H E BLOOD GROUPS BY R. R. RACE -4number of the families investigated by Dr Walton have been tested for the blood groupu and the details are recorded in Table 8. The main reason for doing the tests was to contribute information towards showing whether any of the dystrophy genes and the blood-group genes are linked or not. But the groups proved useful in another way, for they disclosed extramarital children in two families, and as a result these two families provide much weightier evidence for the manner of inheritance of the disease than do more conventional families. The demonstration that the affected children in family D 5 were not all born of the same father is very strong evidence that the Duchenne type of dystrophy is not inherited as an autosomal recessive character. Similarly, the demonstration of an extramarital child in family F 1, who suffers like her mother and half sibs from the facioscapulohumeral type of dystrophy, lends strong support to the view taken by Dr Walton that this type of the disease depends on the action of an autosomal gene with a dominant effect. RESULTS Duchenne type. The pedigrees have been
Annals of Human Genetics – Wiley
Published: Sep 1, 1955
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