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Neuropsychiatric disorders in patients with neurocysticercosis

Neuropsychiatric disorders in patients with neurocysticercosis INTRODUCTIONNeurocysticercosis (NCC), a common parasitic disease affecting the nervous system (Del Brutto, ), is endemic in developing countries in Asia, Africa, and America. Its frequency increases in developed countries as a result of human migrations (John et al., ). Clinical disturbances include epilepsy, intracranial hypertension, and focal neurological deficits (Del Brutto, ). A prospective study (Forlenza et al., ) with 38 NCC outpatients showed that 15% had severe cognitive dysfunction, 52% had depression, and 15% had psychosis. A study including 50 patients with NCC and epilepsy (Srivastava, Chadda, Bala, & Majumdar, ) also reported a high frequency of mental disturbances (68%). Depressive and anxiety disorders were the most frequent. The purpose of this study was to explore the presence of neuropsychiatric disorders in patients with NCC.METHODSThis case‐control study was approved by the Institutional Research Committee and the Ethics Committee of the National Institute of Neurology and Neurosurgery of Mexico, according to the provisions of the Declaration of Helsinki (as revised in Edinburgh 2000). Subjects gave their informed consent. Anonymity has been preserved.We included untreated patients between 18 and 70 years of age, with a definitive diagnosis of NCC according to international diagnostic criteria (Del Brutto, ), through a nonprobabilistic consecutive http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Asia-Pacific Psychiatry Wiley

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References (11)

Publisher
Wiley
Copyright
© 2017 John Wiley & Sons Australia, Ltd
ISSN
1758-5864
eISSN
1758-5872
DOI
10.1111/appy.12250
pmid
27496560
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONNeurocysticercosis (NCC), a common parasitic disease affecting the nervous system (Del Brutto, ), is endemic in developing countries in Asia, Africa, and America. Its frequency increases in developed countries as a result of human migrations (John et al., ). Clinical disturbances include epilepsy, intracranial hypertension, and focal neurological deficits (Del Brutto, ). A prospective study (Forlenza et al., ) with 38 NCC outpatients showed that 15% had severe cognitive dysfunction, 52% had depression, and 15% had psychosis. A study including 50 patients with NCC and epilepsy (Srivastava, Chadda, Bala, & Majumdar, ) also reported a high frequency of mental disturbances (68%). Depressive and anxiety disorders were the most frequent. The purpose of this study was to explore the presence of neuropsychiatric disorders in patients with NCC.METHODSThis case‐control study was approved by the Institutional Research Committee and the Ethics Committee of the National Institute of Neurology and Neurosurgery of Mexico, according to the provisions of the Declaration of Helsinki (as revised in Edinburgh 2000). Subjects gave their informed consent. Anonymity has been preserved.We included untreated patients between 18 and 70 years of age, with a definitive diagnosis of NCC according to international diagnostic criteria (Del Brutto, ), through a nonprobabilistic consecutive

Journal

Asia-Pacific PsychiatryWiley

Published: Jun 1, 2017

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