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Natural selection: a study of ABO, Rh and erythrocyte acid phosphatase types among aborters and non‐aborters

Natural selection: a study of ABO, Rh and erythrocyte acid phosphatase types among aborters and... Natural selection: a study of ABO, Rh and erythrocyte acid phosphatase types among aborters and non -aborters BY L. Y. c. LA1 AND G. H. vos School of Human Genetics, University of New South Wales, Kensington, Australia, and King Edward Memorial Hospital for Women, Subiaw, Western Australia The discovery over 20 years ago of foetal loss due to maternal-foetal differences in the Rh blood-group system has focused attention on the role of blood groups and inherited protein types in natural selection. In general the current approaches fall into at least six classes comprising heterosis and gene interaction, susceptibility to diseases, disturbed segregation frequencies, phenotypic frequencies between age-groups or between sexes, prezygotic selection and incompatibility reactions. Most of the published studies have centred on incompatibility reactions. Apart from the classical example of Rh incompatibility leading to haemolytic disease of the newborn, maternal-foetal incompatibility reactions have been shown to occur in the ABO blood-group system. These were first noted by Hirszfeld & Zborowski (1926), who discovered a deficiency of group A children in families where the mother is group 0 and the father group A. This finding was confimed by Levine (1943) and by Waterhouse & Hogben (1947), who showed http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Natural selection: a study of ABO, Rh and erythrocyte acid phosphatase types among aborters and non‐aborters

LAI, L. Y. C.; VOS, G. H.
Annals of Human Genetics , Volume 31 (3) – Jan 1, 1968
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References (42)

Publisher
Wiley
Copyright
Copyright © 1968 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1968.tb00558.x
Publisher site
See Article on Publisher Site

Abstract

Natural selection: a study of ABO, Rh and erythrocyte acid phosphatase types among aborters and non -aborters BY L. Y. c. LA1 AND G. H. vos School of Human Genetics, University of New South Wales, Kensington, Australia, and King Edward Memorial Hospital for Women, Subiaw, Western Australia The discovery over 20 years ago of foetal loss due to maternal-foetal differences in the Rh blood-group system has focused attention on the role of blood groups and inherited protein types in natural selection. In general the current approaches fall into at least six classes comprising heterosis and gene interaction, susceptibility to diseases, disturbed segregation frequencies, phenotypic frequencies between age-groups or between sexes, prezygotic selection and incompatibility reactions. Most of the published studies have centred on incompatibility reactions. Apart from the classical example of Rh incompatibility leading to haemolytic disease of the newborn, maternal-foetal incompatibility reactions have been shown to occur in the ABO blood-group system. These were first noted by Hirszfeld & Zborowski (1926), who discovered a deficiency of group A children in families where the mother is group 0 and the father group A. This finding was confimed by Levine (1943) and by Waterhouse & Hogben (1947), who showed

Journal

Annals of Human Genetics – Wiley

Published: Jan 1, 1968

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