Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Román, F. Fernández‐Avilés (2006)
The role of noninvasive imaging techniques in the assessment of stem cell therapy after acute myocardial infarctionNature Clinical Practice Cardiovascular Medicine, 3 Suppl 1
J. Garot, T. Unterseeh, E. Teiger, S. Champagne, B. Chazaud, R. Gherardi, L. Hittinger, P. Guéret, A. Rahmouni (2003)
Magnetic resonance imaging of targeted catheter-based implantation of myogenic precursor cells into infarcted left ventricular myocardium.Journal of the American College of Cardiology, 41 10
T. Kofidis, D. Lebl, E. Martinez, G. Hoyt, Masashi Tanaka, R. Robbins (2005)
Novel Injectable Bioartificial Tissue Facilitates Targeted, Less Invasive, Large-Scale Tissue Restoration on the Beating Heart After Myocardial InjuryCirculation, 112
C. Briguori, B. Reimers, C. Sarais, M. Napodano, P. Pascotto, G. Azzarello, M. Bregni, A. Porcellini, O. Vinante, P. Zanco, C. Peschle, G. Condorelli, A. Colombo (2006)
Direct intramyocardial percutaneous delivery of autologous bone marrow in patients with refractory myocardial angina.American heart journal, 151 3
Amit Patel, L. Geffner, R. Viña, J. Saslavsky, H. Urschel, R. Kormos, F. Benetti (2005)
Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: a prospective randomized study.The Journal of thoracic and cardiovascular surgery, 130 6
T. Freyman, G. Polin, Hashim Osman, J. Crary, Minmin Lu, Lan Cheng, M. Palasis, R. Wilensky (2006)
A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction.European heart journal, 27 9
K. Christman, A. Vardanian, Qizhi Fang, R. Sievers, H. Fok, R. Lee (2004)
Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium.Journal of the American College of Cardiology, 44 3
C. Rajnoch, Chachques Jc, A. Berrebi, Patrick Bruneval, M.-O. Benoit, A. Carpentier (2001)
Cellular therapy reverses myocardial dysfunction.The Journal of thoracic and cardiovascular surgery, 121 5
J. Chachques, Corinne Salanson-Lajos, P. Lajos, A. Shafy, Adel Alshamry, A. Carpentier (2005)
Cellular Cardiomyoplasty for Myocardial RegenerationAsian Cardiovascular and Thoracic Annals, 13
M. Penicka, P. Widimsky, P. Kobylka, T. Kozák, O. Lang (2005)
Early Tissue Distribution of Bone Marrow Mononuclear Cells After Transcoronary Transplantation in a Patient With Acute Myocardial InfarctionCirculation, 112
P. Karmarkar, D. Kraitchman, I. Izbudak, L. Hofmann, L. Amado, D. Fritzges, R. Young, M. Pittenger, J. Bulte, E. Atalar (2004)
MR‐trackable intramyocardial injection catheterMagnetic Resonance in Medicine, 51
C. Teng, Jun Luo, R. Chiu, D. Shum-Tim (2006)
Massive mechanical loss of microspheres with direct intramyocardial injection in the beating heart: implications for cellular cardiomyoplasty.The Journal of thoracic and cardiovascular surgery, 132 3
M. Saeed, D. Saloner, Oliver Weber, Alastair Martin, Christine Henk, Charles Higgins (2005)
MRI in guiding and assessing intramyocardial therapyEuropean Radiology, 15
(2004)
ransplantation of Progenitor Cells nd Regeneration Enhancement n Acute Myocardial Infarction
E. Monnet, J. Chachques (2005)
Animal models of heart failure: what is new?The Annals of thoracic surgery, 79 4
A. Schaefer, G. Meyer, M. Fuchs, G. Klein, M. Kaplan, K. Wollert, H. Drexler (2006)
Impact of intracoronary bone marrow cell transfer on diastolic function in patients after acute myocardial infarction: results from the BOOST trial.European heart journal, 27 8
J. Herreros, F. Prósper, Ana Pérez, J. Gavira, M. García-Velloso, J. Barba, P. Sánchez, C. Cañizo, G. Rábago, J. Martí-Climent, Milagros Hernández, N. López-Holgado, J. González-Santos, C. Martín-Luengo, E. Alegrı́a (2003)
Autologous intramyocardial injection of cultured skeletal muscle-derived stem cells in patients with non-acute myocardial infarction.European heart journal, 24 22
(2005)
tracoronary injection of CD 133 - positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction : Feasibility and safety
Schachinger Schachinger, Assmus Assmus, Britten Britten (2004)
Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: Final one‐year results of the TOPCARE‐AMI TrialJ Am Coll Cardiol, 44
C. Rivière, F. Boudghène, F. Gazeau, J. Roger, J. Pons, J. Laissy, É. Allaire, J. Michel, D. Letourneur, J. Deux (2005)
Iron oxide nanoparticle-labeled rat smooth muscle cells: cardiac MR imaging for cell graft monitoring and quantitation.Radiology, 235 3
C. Rickers, R. Gallegos, R. Seethamraju, Xiaoen Wang, C. Swingen, Avinash Jayaswal, E. Rahrmann, Z. Kastenberg, Christina Clarkson, R. Bianco, T. O'Brian, C. Verfaillie, R. Bolman, N. Wilke, M. Jerosch-Herold (2004)
Applications of magnetic resonance imaging for cardiac stem cell therapy.Journal of interventional cardiology, 17 1
J Thorac Cardiovasc Surg, 132
J. Bartunek, M. Vanderheyden, B. Vandekerckhove, S. Mansour, B. Bruyne, P. Bondt, I. haute, Nele Lootens, G. Heyndrickx, W. Wijns (2005)
Intracoronary Injection of CD133-Positive Enriched Bone Marrow Progenitor Cells Promotes Cardiac Recovery After Recent Myocardial Infarction: Feasibility and SafetyCirculation, 112
S. Pislaru, Y. Ni, C. Pislaru, H. Bosmans, Y. Miao, J. Bogaert, S. Dymarkowski, W. Semmler, G. Marchal, F. Werf (1999)
Noninvasive measurements of infarct size after thrombolysis with a necrosis-avid MRI contrast agent.Circulation, 99 5
D. Kraitchman, A. Heldman, E. Atalar, L. Amado, B. Martin, M. Pittenger, J. Hare, J. Bulte (2003)
In Vivo Magnetic Resonance Imaging of Mesenchymal Stem Cells in Myocardial InfarctionCirculation: Journal of the American Heart Association, 107
J. Chachques, C. Acar, J. Herreros, J. Trainini, F. Prósper, N. D'attellis, J. Fabiani, A. Carpentier (2004)
Cellular cardiomyoplasty: clinical application.The Annals of thoracic surgery, 77 3
Richard Thompson, Cyrus Parsa, E. Bos, B. Davis, E. Toloza, I. Klem, D. Glower, Doris Taylor (2004)
Video-assisted thoracoscopic transplantation of myoblasts into the heart.The Annals of thoracic surgery, 78 1
W. Sherman, T. Martens, J. Viles‐Gonzalez, T. Siminiak (2006)
Catheter-based delivery of cells to the heartNature Clinical Practice Cardiovascular Medicine, 3 Suppl 1
V. Fuster, J. Sanz, J. Viles‐Gonzalez, S. Rajagopalan (2006)
The utility of magnetic resonance imaging in cardiac tissue regeneration trialsNature Clinical Practice Cardiovascular Medicine, 3 Suppl 1
E. Perin, H. Dohmann, R. Borojevic, S. Silva, A. Sousa, G. Silva, C. Mesquita, L. Belém, W. Vaughn, F. Rangel, J. Assad, A. Carvalho, R. Branco, M. Rossi, H. Dohmann, J. Willerson (2004)
Improved Exercise Capacity and Ischemia 6 and 12 Months After Transendocardial Injection of Autologous Bone Marrow Mononuclear Cells for Ischemic CardiomyopathyCirculation, 110
A. Mathur, John Martin (2004)
Stem cells and repair of the heartThe Lancet, 364
R. Kim, D. Fieno, T. Parrish, Kathleen Harris, Enn‐ling Chen, Orlando Simonetti, J. Bundy, J. Finn, F. Klocke, R. Judd (1999)
Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function.Circulation, 100 19
F. Fernández‐Avilés, J. Román, J. García-Frade, M. Fernández, M. Penarrubia, L. Fuente, M. Gómez-Bueno, A. Cantalapiedra, Jesús Fernández, Oliver Gutiérrez, P. Sánchez, C. Hernández, R. Sanz, J. García-Sancho, Ana Sánchez (2004)
Experimental and Clinical Regenerative Capability of Human Bone Marrow Cells After Myocardial InfarctionCirculation Research, 95
J. Hill, A. Dick, V. Raman, Richard Thompson, Zu-Xi Yu, K. Hinds, B. Pessanha, M. Guttman, Timothy Varney, B. Martin, C. Dunbar, E. McVeigh, R. Lederman (2003)
Serial Cardiac Magnetic Resonance Imaging of Injected Mesenchymal Stem CellsCirculation: Journal of the American Heart Association, 108
R. Laham, M. Post, M. Rezaee, Laurel Donnell-Fink, J. Wykrzykowska, S. Lee, D. Baim, F. Sellke (2005)
TRANSENDOCARDIAL AND TRANSEPICARDIAL INTRAMYOCARDIAL FIBROBLAST GROWTH FACTOR-2 ADMINISTRATION: MYOCARDIAL AND TISSUE DISTRIBUTIONDrug Metabolism and Disposition, 33
E. Küstermann, W. Roell, M. Breitbach, S. Wecker, D. Wiedermann, C. Buehrle, A. Welz, J. Hescheler, B. Fleischmann, M. Hoehn (2005)
Stem cell implantation in ischemic mouse heart: a high‐resolution magnetic resonance imaging investigationNMR in Biomedicine, 18
Alberto Weber, I. Pedrosa, A. Kawamoto, N. Himes, J. Munasinghe, T. Asahara, N. Rofsky, Douglas Losordo (2004)
Magnetic resonance mapping of transplanted endothelial progenitor cells for therapeutic neovascularization in ischemic heart disease.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 26 1
J. Chachques, F. Duarte, B. Cattadori, A. Shafy, N. Lila, G. Chatellier, J. Fabiani, A. Carpentier (2004)
Angiogenic growth factors and/or cellular therapy for myocardial regeneration: a comparative study.The Journal of thoracic and cardiovascular surgery, 128 2
A. Dick, M. Guttman, V. Raman, D. Peters, B. Pessanha, J. Hill, Scott Smith, G. Scott, E. McVeigh, R. Lederman (2003)
Magnetic Resonance Fluoroscopy Allows Targeted Delivery of Mesenchymal Stem Cells to Infarct Borders in SwineCirculation: Journal of the American Heart Association, 108
Aims: We compared two procedures for local myocardial treatment: transepicardial versus transendocardial catheter injection. Transepicardial injections were performed under direct surgical visualization whereas transendocardial injections were performed using electrophysiological guidance. Methods: A left ventricle (LV) myocardial infarction (MI) was surgically created in 14 sheep. At 3 months, gadolinium was injected IV followed by the injection of super paramagnetic iron oxide (SPIO) into MI. Animals were divided in two groups: transepicardial injection (Group I) versus transendocardial (Group II) using “Cell‐Fix” catheter injection. This catheter was developed to identify by electrophysiology the infarcted area and to stabilize injections suctioning the device to the endocardium. Postgadolinium delayed‐enhancement magnetic resonance imaging (MRI) was performed to stain the infarct size. SPIO injections were used to assess the magnitude of the treated area. The ratio between SPIO black stained treatment areas and white gadolinium stained infarcted areas was calculated using MRI. Results: The electrophysiological recordings by the catheter for the MI versus normal LV wall were: R wave amplitude 4.16 versus 12.08 mV (P = 0.003), slew rate (slope of the signal) 0.36 V/s versus 1.04 V/s (P = 0.008). The ratio of the SPIO diffusion into the MI was 41.2 ± 8.1% for surgical and 63.7 ± 8.2% for percutaneous endocardial injections (P = 0.0132). Conclusion: MRI allows evaluation of the extent of local myocardial treatments. The differences shown between epicardial and endocardial injections concerning the distribution of SPIO can be justified by the methodology of injection and by a more precise MI detection by electrophysiology. In conclusion, electrophysiological recordings to guide injections is superior to direct surgical visualization in terms of injecting into infarcted tissue.
Journal of Interventional Cardiology – Wiley
Published: Jun 1, 2007
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.