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Ann. Hum. Genet. (1997), 61, 283±285 283 Printed in Great Britain Reviews Human Molecular Genetics.ByT.Strachan and mechanisms leading to DNA mutation and A. P. Read. Oxford : Bios Scienti®c instability with examples taken from the human Publishers. 1996. ISBN 1 872748 69 4. Pp. genome. 596Index. £29.95. The next set of chapters describe physical and genetic mapping and, again, these chapters are It is a pleasure to review this book by very comprehensive and up to date, including Professors Strachan and Read. The ®eld of a detailed description of the Human Genome human molecular genetics has expanded rapidly Project. We are then taken through the steps and with several universities now offering BSc involved in identifying human disease genes, the degrees in human genetics there is a need for pathological effects of mutations in these genes, advanced text-books on the subject. and then the technical and ethical aspects of The book begins with a standard introduction genetic testing of individuals and populations. to DNA structure, replication, transcription and The ®nal chapters describe somatic mutations translation. In the section on transcription it is and cancer, the analysis of complex diseases, how nice to see a description of cis-acting elements to
Annals of Human Genetics – Wiley
Published: Jan 1, 1997
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