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Modern management of phagocyte defects

Modern management of phagocyte defects Phagocytic neutrophil granulocytes are among the first immune cells active at sites of infection, forming an important first‐line defense against invading microorganisms. Congenital immune defects concerning these phagocytes may be due to reduced neutrophil numbers or function. Management of affected patients depends on the type and severity of disease. Here, we provide an overview of causes and treatment of diseases associated with congenital neutropenia, as well as defects of the phagocytic respiratory burst. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Allergy and Immunology Wiley

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References (106)

Publisher
Wiley
Copyright
Copyright © 2017 John Wiley & Sons A/S
ISSN
0905-6157
eISSN
1399-3038
DOI
10.1111/pai.12654
pmid
27612320
Publisher site
See Article on Publisher Site

Abstract

Phagocytic neutrophil granulocytes are among the first immune cells active at sites of infection, forming an important first‐line defense against invading microorganisms. Congenital immune defects concerning these phagocytes may be due to reduced neutrophil numbers or function. Management of affected patients depends on the type and severity of disease. Here, we provide an overview of causes and treatment of diseases associated with congenital neutropenia, as well as defects of the phagocytic respiratory burst.

Journal

Pediatric Allergy and ImmunologyWiley

Published: Mar 1, 2017

Keywords: ; ; ; ; ; ;

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