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Mimer : an automated spreadsheet‐based crystallization screening system

Mimer : an automated spreadsheet‐based crystallization screening system In this paper, a simple low‐cost alternative to large commercial systems for preparing macromolecular crystallization conditions is described. Using an intuitive spreadsheet‐based approach, the system allows the rapid calculation of relevant pipetting volumes given known stock‐solution concentrations and incorporates the automatic design of custom crystallization screens via the incomplete‐factorial and grid‐screen approaches. Automated dispensing of the resulting crystallization screens is achieved using a generic and relatively inexpensive liquid handler. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Crystallographica Section F Wiley

Mimer : an automated spreadsheet‐based crystallization screening system

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References (19)

Publisher
Wiley
Copyright
International Union of Crystallography, 2013
ISSN
1744-3091
eISSN
1744-3091
DOI
10.1107/S1744309113014425
pmid
23832216
Publisher site
See Article on Publisher Site

Abstract

In this paper, a simple low‐cost alternative to large commercial systems for preparing macromolecular crystallization conditions is described. Using an intuitive spreadsheet‐based approach, the system allows the rapid calculation of relevant pipetting volumes given known stock‐solution concentrations and incorporates the automatic design of custom crystallization screens via the incomplete‐factorial and grid‐screen approaches. Automated dispensing of the resulting crystallization screens is achieved using a generic and relatively inexpensive liquid handler.

Journal

Acta Crystallographica Section FWiley

Published: Jul 1, 2013

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