Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Luminescent Silver–Purine Double Helicate: Synthesis, Self‐Assembly and Antibacterial Action

Luminescent Silver–Purine Double Helicate: Synthesis, Self‐Assembly and Antibacterial Action The synthesis, self‐assembly and antibacterial activity of a luminescent silver–purine double helicate is reported. The structure of the newly synthesized silver‐supported helicate [C36H24N16O4Cl5Ag1] was unambiguously characterized by single‐crystal X‐ray crystallography. It exhibited a bright bluish‐green emission (λmax=460 nm), when excited with 380 nm light. Microscopic investigations showed that the complex has a propensity to self‐assemble into nanospheres. The antibacterial activity of this silver‐containing helicate was studied against both Gram‐positive and Gram‐negative bacteria. MIC (minimal inhibitory concentration) values showed that the complex is very active against Gram‐negative bacteria. Further internalization of the silver complex into E. coli bacteria was mapped with the help of microscopic techniques. These results are significant as silver was recently found to enhance antibiotic action against Gram‐negative bacteria, raising hope in countering severe bacterial infections. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png ChemPlusChem Wiley

Luminescent Silver–Purine Double Helicate: Synthesis, Self‐Assembly and Antibacterial Action

Loading next page...
 
/lp/wiley/luminescent-silver-purine-double-helicate-synthesis-self-assembly-and-EsfEQDkpjQ

References (88)

Publisher
Wiley
Copyright
© 2016 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim
ISSN
2192-6506
eISSN
2192-6506
DOI
10.1002/cplu.201600293
Publisher site
See Article on Publisher Site

Abstract

The synthesis, self‐assembly and antibacterial activity of a luminescent silver–purine double helicate is reported. The structure of the newly synthesized silver‐supported helicate [C36H24N16O4Cl5Ag1] was unambiguously characterized by single‐crystal X‐ray crystallography. It exhibited a bright bluish‐green emission (λmax=460 nm), when excited with 380 nm light. Microscopic investigations showed that the complex has a propensity to self‐assemble into nanospheres. The antibacterial activity of this silver‐containing helicate was studied against both Gram‐positive and Gram‐negative bacteria. MIC (minimal inhibitory concentration) values showed that the complex is very active against Gram‐negative bacteria. Further internalization of the silver complex into E. coli bacteria was mapped with the help of microscopic techniques. These results are significant as silver was recently found to enhance antibiotic action against Gram‐negative bacteria, raising hope in countering severe bacterial infections.

Journal

ChemPlusChemWiley

Published: Dec 1, 2016

Keywords: ; ; ;

There are no references for this article.