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Long‐Term Outcome after Transcatheter Closure of Postinfarction Ventricular Septal Rupture

Long‐Term Outcome after Transcatheter Closure of Postinfarction Ventricular Septal Rupture Objectives We report the long‐term all‐cause mortality and procedure‐related complication rate following transcatheter closure of postinfarction ventricular septal rupture (VSR) in a single tertiary center. Background VSR is an exceedingly serious and deathly complication to myocardial infarction. Surgical closure has previously been the treatment of choice, but in the last decade a transcatheter approach has gained ground. However, reports on long‐term survival are still sparse and experience is often restricted to large tertiary centers with high flow of patients. Methods From January 2000 to April 2013, 9 patients underwent transcatheter closure of a VSR at Aarhus University Hospital. Primary device closure was chosen mainly because of significant risk factors against surgery. Our major endpoints were 30‐day, 1‐year, and 5‐year mortality and years of survival until time of evaluation. Results Our cohort had a mean age of 75.1 ± 8.4 years, and the median time from VSR to closure was 16 days (2–346). The 30‐day, 1‐year, and 5‐year mortality rates were 11.1%, 33.3%, and 62.5%, respectively. Mean time of postprocedural survival was 4.6 ± 4.4 years at the time of review. Three patients were still alive at the time of review, 1 with a shock‐index <1 at the time of VSR closure. Conclusions As a single medium‐sized tertiary center, we report lower short‐ and long‐term mortality rates compared with most published data on outcome after surgical closure. Our results are comparable to the few previously published reports on transcatheter closure of postinfarction VSRs. (J Interven Cardiol 2014;27:509–515) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Interventional Cardiology Wiley

Long‐Term Outcome after Transcatheter Closure of Postinfarction Ventricular Septal Rupture

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References (22)

Publisher
Wiley
Copyright
"© 2014 Wiley Periodicals, Inc."
ISSN
0896-4327
eISSN
1540-8183
DOI
10.1111/joic.12146
pmid
25155883
Publisher site
See Article on Publisher Site

Abstract

Objectives We report the long‐term all‐cause mortality and procedure‐related complication rate following transcatheter closure of postinfarction ventricular septal rupture (VSR) in a single tertiary center. Background VSR is an exceedingly serious and deathly complication to myocardial infarction. Surgical closure has previously been the treatment of choice, but in the last decade a transcatheter approach has gained ground. However, reports on long‐term survival are still sparse and experience is often restricted to large tertiary centers with high flow of patients. Methods From January 2000 to April 2013, 9 patients underwent transcatheter closure of a VSR at Aarhus University Hospital. Primary device closure was chosen mainly because of significant risk factors against surgery. Our major endpoints were 30‐day, 1‐year, and 5‐year mortality and years of survival until time of evaluation. Results Our cohort had a mean age of 75.1 ± 8.4 years, and the median time from VSR to closure was 16 days (2–346). The 30‐day, 1‐year, and 5‐year mortality rates were 11.1%, 33.3%, and 62.5%, respectively. Mean time of postprocedural survival was 4.6 ± 4.4 years at the time of review. Three patients were still alive at the time of review, 1 with a shock‐index <1 at the time of VSR closure. Conclusions As a single medium‐sized tertiary center, we report lower short‐ and long‐term mortality rates compared with most published data on outcome after surgical closure. Our results are comparable to the few previously published reports on transcatheter closure of postinfarction VSRs. (J Interven Cardiol 2014;27:509–515)

Journal

Journal of Interventional CardiologyWiley

Published: Oct 1, 2014

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