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Linkage analysis and family classification under heterogeneity

Linkage analysis and family classification under heterogeneity Summary Heterogeneity of the recombination fraction may or may not involve a mixture of two groups of elements. For the mixture situation (families with or without linkage between two gene loci), Morton's homogeneity test is compared with another test (Admixture test) with respect to significance level, power, parameter estimation and classification of families. The Admixture test is shown generally to have superior properties in this situation. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Linkage analysis and family classification under heterogeneity

OTT, JURG
Annals of Human Genetics , Volume 47 (4) – Oct 1, 1983
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References (12)

Publisher
Wiley
Copyright
Copyright © 1983 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
DOI
10.1111/j.1469-1809.1983.tb01001.x
Publisher site
See Article on Publisher Site

Abstract

Summary Heterogeneity of the recombination fraction may or may not involve a mixture of two groups of elements. For the mixture situation (families with or without linkage between two gene loci), Morton's homogeneity test is compared with another test (Admixture test) with respect to significance level, power, parameter estimation and classification of families. The Admixture test is shown generally to have superior properties in this situation.

Journal

Annals of Human Genetics – Wiley

Published: Oct 1, 1983

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