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A Pharmacogenetic Study of Escitalopram in Autism Spectrum Disorders Thomas Owley, Camille W. Brune, Jeff Salt, Laura Walton, Steve Guter, Nelson Ayuyao, Robert D. Gibbons, Bennett L. Leventhal, and Edwin H. Cook LAY ABSTRACT Many children with Autism Spectrum Disorders have problems with anxiety, obsessions, compulsions, and insisting that things stay the same. When other interventions are not adequately helping the child deal with these difficulties, sometimes medication is considered a treatment option. Serotonin is inactivated when it is taken back into nerve cells by a protein called the serotonin transporter. Escitalopram blocks this protein. We wanted to know if variation in the gene that produces the protein target for escitalopram would be related to response to this treatment. © 2010 INSAR / Wiley Periodicals, Inc. Article Citation: Autism Res 2010, 3: 1–7 . DOI: 10.1002/aur.109 MEG Detection of Delayed Auditory Evoked Responses in Autism Spectrum Disorders: Towards an Imaging Biomarker for Autism Timothy P.L. Roberts, Sarah Y. Khan, Mike Rey, Justin F. Monroe, Katelyn Cannon, Lisa Blaskey, Sarah Woldoff, Saba Qasmieh, Mike Gandal, Gwen L. Schmidt, Deborah M. Zarnow, Susan E. Levy, and J. Christopher Edgar LAY ABSTRACT Auditory and speech problems are frequently observed in individuals
Autism Research – Wiley
Published: Feb 1, 2010
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