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Is there a place for antihistamines in the treatment of perennial asthma?

Is there a place for antihistamines in the treatment of perennial asthma? PEDIATRIC ALLERGY AND IMMUNOLOGY ISSN 0906-578$ Is there a place for antihistamines in the treatment of perennial asthma? Kjellmann N-IM. Is there a place for antihistamines in the treatment of perennial asthma? Pediatr Allergy Immunol 1993: 4 (Suppl 4): 3843. 0Munksgaard 1993. I N,-l. M. Kiellman Department of Pediatrics, University Hospital, LinkBping, Sweden N.4. Max Kjellman, M.D., Department of Pediatrics, University Hospital, S-58185 Linkoping, Sweden Key words: adolescent - antihistamine - bronchial asthma - children - perennial Bronchial asthma causes considerable suffering and loss of days at school for children and adolescents and high costs for society (1). Between 4% and 10% of schoolchildren are current asthmatics, and the asthma prevalence is increasing (2). In more than 80% of cases, asthma coincides with other manifestations of atopic disease, notably allergic rhinitis and atopic eczema (dermatitis). Asthma is characterized by variable bronchial obstruction; part of this is due to increased muscular tone and is therefore readily reversible with modern selective bronchodilators (that is, b2-agonists) (3). There is also inflammatory oedema and infiltration of a variety of inflammatory cells together with secondary effects resulting from repair after previous attacks. Histopathologically, there is eosinophilic bronchitis but also an increase in the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Allergy and Immunology Wiley

Is there a place for antihistamines in the treatment of perennial asthma?

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References (36)

Publisher
Wiley
Copyright
Copyright © 1993 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0905-6157
eISSN
1399-3038
DOI
10.1111/j.1399-3038.1993.tb00337.x
Publisher site
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Abstract

PEDIATRIC ALLERGY AND IMMUNOLOGY ISSN 0906-578$ Is there a place for antihistamines in the treatment of perennial asthma? Kjellmann N-IM. Is there a place for antihistamines in the treatment of perennial asthma? Pediatr Allergy Immunol 1993: 4 (Suppl 4): 3843. 0Munksgaard 1993. I N,-l. M. Kiellman Department of Pediatrics, University Hospital, LinkBping, Sweden N.4. Max Kjellman, M.D., Department of Pediatrics, University Hospital, S-58185 Linkoping, Sweden Key words: adolescent - antihistamine - bronchial asthma - children - perennial Bronchial asthma causes considerable suffering and loss of days at school for children and adolescents and high costs for society (1). Between 4% and 10% of schoolchildren are current asthmatics, and the asthma prevalence is increasing (2). In more than 80% of cases, asthma coincides with other manifestations of atopic disease, notably allergic rhinitis and atopic eczema (dermatitis). Asthma is characterized by variable bronchial obstruction; part of this is due to increased muscular tone and is therefore readily reversible with modern selective bronchodilators (that is, b2-agonists) (3). There is also inflammatory oedema and infiltration of a variety of inflammatory cells together with secondary effects resulting from repair after previous attacks. Histopathologically, there is eosinophilic bronchitis but also an increase in the

Journal

Pediatric Allergy and Immunology – Wiley

Published: Dec 1, 1993

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