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Shailendra Giri, A. Karakoti, R. Graham, Jacie Maguire, C. Reilly, S. Seal, R. Rattan, V. Shridhar (2013)
Nanoceria: A Rare-Earth Nanoparticle as a Novel Anti-Angiogenic Therapeutic Agent in Ovarian CancerPLoS ONE, 8
Cassandra Korsvik, S. Patil, S. Seal, W. Self (2007)
Superoxide dismutase mimetic properties exhibited by vacancy engineered ceria nanoparticles.Chemical communications, 10
R. Gorte, S. Zhao (2005)
Studies of the water-gas-shift reaction with ceria-supported precious metalsCatalysis Today, 104
(1973)
J. Chem. Soc. Dalton Trans
A. Karakoti, N. Monteiro-Riviere, R. Aggarwal, Jack Davis, R. Narayan, W. Self, J. McGinnis, S. Seal (2008)
Nanoceria as antioxidant: Synthesis and biomedical applicationsJOM, 60
(1689)
Free Radical Biol. Med
Xiao He, Hai-feng Zhang, Yuhui Ma, W. Bai, Zhiyong Zhang, Kai Lu, Yayun Ding, Yuliang Zhao, Z. Chai (2010)
Lung deposition and extrapulmonary translocation of nano-ceria after intratracheal instillationNanotechnology, 21
(2012)
Toxicol. Appl. Pharmacol
(2013)
Z. Pang, X. Jiang, Sci. Rep
I. Celardo, J. Pedersen, E. Traversa, L. Ghibelli (2011)
Pharmacological potential of cerium oxide nanoparticles.Nanoscale, 3 4
Ajay Karakoti, Soumen Das, Suntharampillai Thevuthasan, Sudipta Seal (2011)
PEGylierte anorganische NanopartikelAngewandte Chemie, 123
R. Yokel, M. Tseng, Mo Dan, J. Unrine, U. Graham, Peng Wu, E. Grulke (2013)
Biodistribution and biopersistence of ceria engineered nanomaterials: size dependence.Nanomedicine : nanotechnology, biology, and medicine, 9 3
(2005)
Appl. Phys. Lett
(2009)
J. Am. Chem. Soc
(2010)
Decommissioning, Immobilisation and Management of Nuclear Waste for Disposal
S. Turner, S. Lazar, B. Freitag, R. Egoavil, J. Verbeeck, S. Put, Y. Strauven, G. Tendeloo (2011)
High resolution mapping of surface reduction in ceria nanoparticles.Nanoscale, 3 8
Sarita Hardas, D. Butterfield, R. Sultana, M. Tseng, Mo Dan, Rebecca Florence, J. Unrine, U. Graham, Peng Wu, E. Grulke, R. Yokel (2010)
Brain distribution and toxicological evaluation of a systemically delivered engineered nanoscale ceria.Toxicological sciences : an official journal of the Society of Toxicology, 116 2
S. Deshpande, S. Patil, S. Kuchibhatla, S. Seal (2005)
Size dependency variation in lattice parameter and valency states in nanocrystalline cerium oxideApplied Physics Letters, 87
Michael Tseng, Xiaoqin Lu, Xiaoxian Duan, Sarita Hardas, R. Sultana, Peng Wu, J. Unrine, U. Graham, D. Butterfield, E. Grulke, R. Yokel (2012)
Alteration of hepatic structure and oxidative stress induced by intravenous nanoceria.Toxicology and applied pharmacology, 260 2
J. Gilman (2001)
NanotechnologyMaterial Research Innovations, 5
Peng Zhang, Yuhui Ma, Zhiyong Zhang, Xiao He, Jing Zhang, Zhi Guo, R. Tai, Yuliang Zhao, Z. Chai (2012)
Biotransformation of ceria nanoparticles in cucumber plants.ACS nano, 6 11
F. Rancan, B. Nazemi, S. Rautenberg, M. Ryll, S. Hadam, Q. Gao, S. Hackbarth, S. Haag, C. Graf, E. Rühl, U. Blume-Peytavi, J. Lademann, A. Vogt, M. Meinke (2014)
Ultraviolet radiation and nanoparticle induced intracellular free radicals generation measured in human keratinocytes by electron paramagnetic resonance spectroscopySkin Research and Technology, 20
Xiangyou Liu, Wei Wei, Q. Yuan, Xin Zhang, Ning Li, Yuguang Du, G. Ma, Chunhua Yan, Ding Ma (2012)
Apoferritin-CeO2 nano-truffle that has excellent artificial redox enzyme activity.Chemical communications, 48 26
A. Karakoti, Soumen Das, S. Thevuthasan, S. Seal (2011)
PEGylated inorganic nanoparticles.Angewandte Chemie, 50 9
Talib Pirmohamed, J. Dowding, Sanjay Singh, B. Wasserman, Eric Heckert, A. Karakoti, Jessica King, S. Seal, W. Self (2010)
Nanoceria exhibit redox state-dependent catalase mimetic activity.Chemical communications, 46 16
M. Das, S. Patil, N. Bhargava, J. Kang, L. Riedel, S. Seal, J. Hickman (2007)
Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons.Biomaterials, 28 10
S. Patil, Amanda Sandberg, Eric Heckert, W. Self, S. Seal (2007)
Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential.Biomaterials, 28 31
Jong Kim, Christoffer Åberg, A. Salvati, K. Dawson (2011)
Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population.Nature nanotechnology, 7 1
(2005)
J. Phys. Chem. B
(2010)
Meth. Molec. Bio
C. Kim, Taeho Kim, I. Choi, Min Soh, Dohoung Kim, Youngju Kim, Hyunduk Jang, Hye‐Sung Yang, J. Kim, Hong‐Kyun Park, Seung Park, Sangseung Park, Taekyung Yu, B. Yoon, Seung-Hoon Lee, T. Hyeon (2012)
Ceria nanoparticles that can protect against ischemic stroke.Angewandte Chemie, 51 44
R. Yokel, Tulegenova Au, R. Macphail, Sarita Hardas, D. Butterfield, R. Sultana, M. Goodman, M. Tseng, Mo Dan, H. Haghnazar, J. Unrine, U. Graham, Peng Wu, E. Grulke (2012)
Distribution, elimination, and biopersistence to 90 days of a systemically introduced 30 nm ceria-engineered nanomaterial in rats.Toxicological sciences : an official journal of the Society of Toxicology, 127 1
Ning Li, T. Xia, A. Nel (2008)
The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles.Free radical biology & medicine, 44 9
(2005)
Small, Solid State Phenomena
A. Karakoti, Sanjay Singh, Amit Kumar, M. Malińska, S. Kuchibhatla, K. Woźniak, W. Self, S. Seal (2009)
PEGylated nanoceria as radical scavenger with tunable redox chemistry.Journal of the American Chemical Society, 131 40
Angew Chem . 2011 ; 123 : 1276 Angew Chem . 2011 ; 123 : 2024
CHEMPLUSCHEM COMMUNICATIONS
Lijun Wu, H. Wiesmann, A. Moodenbaugh, R. Klie, Yimei Zhu, D. Welch, M. Suenaga (2004)
Oxidation state and lattice expansion of CeO 2-x nanoparticles as a function of particle sizePhysical Review B, 69
Yu-Hsuan Lee, F. Cheng, H. Chiu, J. Tsai, C. Fang, Chun-Wan Chen, Ying-Jan Wang (2014)
Cytotoxicity, oxidative stress, apoptosis and the autophagic effects of silver nanoparticles in mouse embryonic fibroblasts.Biomaterials, 35 16
(2001)
Chem. Mater
J. Paier, Christopher Penschke, J. Sauer (2013)
Oxygen defects and surface chemistry of ceria: quantum chemical studies compared to experiment.Chemical reviews, 113 6
Jenq-Sheng Chang, K. Chang, D. Hwang, Z. Kong (2007)
In vitro cytotoxicitiy of silica nanoparticles at high concentrations strongly depends on the metabolic activity type of the cell line.Environmental science & technology, 41 6
Huile Gao, Zhi Yang, Shuang Zhang, Shijie Cao, S. Shen, Z. Pang, Xin-guo Jiang (2013)
Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalizationScientific Reports, 3
H. Kalantari (2013)
NanotoxicologyJundishapur Journal of Natural Pharmaceutical Products, 8
W. Stark (2011)
Nanopartikel in biologischen SystemenAngewandte Chemie, 123
T. Walser, L. Limbach, Robert Brogioli, Esther Erismann, L. Flamigni, B. Hattendorf, Markus Juchli, F. Krumeich, C. Ludwig, K. Príkopský, M. Rossier, D. Saner, A. Sigg, S. Hellweg, D. Günther, W. Stark (2012)
Persistence of engineered nanoparticles in a municipal solid-waste incineration plant.Nature nanotechnology, 7 8
Jeremy Willis, Y. Patel, B. Lentz, Shan Yan (2013)
APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stressProceedings of the National Academy of Sciences, 110
(1059)
Proc. Natl. Acad. Sci. USA 2013
(1056)
Chem. Commun
(2011)
Nanoscale
H. Mai, Ling-Dong Sun, Ya‐Wen Zhang, R. Si, Wei Feng, Hong-Peng Zhang, Haichao Liu, Chunhua Yan (2005)
Shape-selective synthesis and oxygen storage behavior of ceria nanopolyhedra, nanorods, and nanocubes.The journal of physical chemistry. B, 109 51
(2013)
Nanomed: Nanotech. Biol. Med
(2007)
Environ. Sci. Technol
(2012)
Toxicol. Sci
J. Gomis, L. Carlos, A. Prevot, A.C.S.C. Teixeira, M. Mora, A. a, R. Vicente, A. Arques (2014)
Catalysis Today
K. Rajesh, P. Mukundan, P. Pillai, V. Nair, K. Warrier (2004)
High-Surface-Area Nanocrystalline Cerium Phosphate through Aqueous Sol−Gel RouteChemistry of Materials, 16
W. Stark (2011)
Nanoparticles in biological systems.Angewandte Chemie, 50 6
L. Limbach, Yuchun Li, R. Grass, T. Brunner, M. Hintermann, M. Muller, Detlef Gunther, W. Stark (2005)
Oxide nanoparticle uptake in human lung fibroblasts: effects of particle size, agglomeration, and diffusion at low concentrations.Environmental science & technology, 39 23
A. Samuni, G. Czapski (1973)
Reaction of cerium(IV) perchlorate with hydrogen peroxideJournal of The Chemical Society-dalton Transactions
R. Yokel, Rebecca Florence, J. Unrine, M. Tseng, U. Graham, Peng Wu, E. Grulke, R. Sultana, Sarita Hardas, D. Butterfield (2009)
Biodistribution and oxidative stress effects of a systemically-introduced commercial ceria engineered nanomaterialNanotoxicology, 3
Jienan Zhang, X. Ju, Ziyu Wu, Taozhe Liu, T. Hu, Yujun Xie, Zehua Zhang (2001)
Structural Characteristics of Cerium Oxide Nanocrystals Prepared by the Microemulsion MethodChemistry of Materials, 13
(2012)
Angew. Chem. Angew. Chem. Int
Subramanian Tamilmani, V. Lowalekar, S. Raghavan, R. Small (2005)
Dissolution Characteristics of Ceria in Ascorbic Acid Solutions with Implications to CleaningSolid State Phenomena, 103-104
S. Haigh, N. Young, H. Sawada, K. Takayanagi, A. Kirkland (2011)
Understanding the In-Situ Reaction of Cerium Oxide Nanoparticles Using Aberration Corrected Exit Wave Restoration and EELSMicroscopy and Microanalysis, 17
R. Misra (2008)
BiomaterialsMaterials Science and Technology, 24
K. Prasse, P. Hildebrandt, D. Dodd (1986)
In Toxicologic PathologyToxicologic Pathology, 14
J. Owen, D. Butterfield (2010)
Measurement of oxidized/reduced glutathione ratio.Methods in molecular biology, 648
The cytotoxicity of ceria ultimately lies in its electronic structure, which is defined by the crystal structure, composition, and size. Despite previous studies focused on ceria uptake, distribution, biopersistance, and cellular effects, little is known about its chemical and structural stability and solubility once sequestered inside the liver. Mechanisms will be presented that elucidate the in vivo transformation in the liver. In vivo processed ceria reveals a particle‐size effect towards the formation of ultrafines, which represent a second generation of ceria. A measurable change in the valence reduction of the second‐generation ceria can be linked to an increased free‐radical scavenging potential. The in vivo processing of the ceria nanoparticles in the liver occurs in temporal relation to the brain cellular and protein clearance responses that stem from the ceria uptake. This information is critical to establish a possible link between cellular processes and the observed in vivo transformation of ceria. The temporal linkage between the reversal of the pro‐oxidant effect (brain) and ceria transformation (liver) suggests a cause–effect relationship.
ChemPlusChem – Wiley
Published: Aug 1, 2014
Keywords: ; ; ; ;
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