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In this issue

In this issue It is an unmitigated tragedy that Pediatric Allergy and Immunology will start the new millennium without Professor Luisa Businco. She has been a regular contributor to the Journal and an enormous support to the Editor in her role on the Editorial Board. I hope that this and all future issues will do justice to her memory. She was always very proud of the Journal as the official publication of the European Society for Pediatric Allergy & Clinical Immunology, to which she was devoted. Our first paper is following a line started by Dr Miceli Sopo in the previous issue in scrutinizing the methodology for studying cord blood T‐cell reactivity ( 1 ). Dr Sopo pleaded for a more rigorous standardization of methodology. Matthias Kopp and colleagues have specifically investigated the influence of cell concentration on proliferation of T cells in response to a number of common allergens and interleukin (IL)‐2. Clearly background activity fell with decreasing cell concentrations, but this occurred to a lesser extent in response to stimulation. Thus lower cell numbers unmasked T‐cell reactivity, which has led the authors to suggest a lower concentration of cells per well for proliferation experiments than has formerly been employed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Allergy and Immunology Wiley

In this issue

Warner, J. O.
Pediatric Allergy and Immunology , Volume 11 (1) – Feb 1, 2000
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References (2)

Publisher
Wiley
Copyright
Copyright © 2000 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0905-6157
eISSN
1399-3038
DOI
10.1034/j.1399-3038.2000.00073.x
Publisher site
See Article on Publisher Site

Abstract

It is an unmitigated tragedy that Pediatric Allergy and Immunology will start the new millennium without Professor Luisa Businco. She has been a regular contributor to the Journal and an enormous support to the Editor in her role on the Editorial Board. I hope that this and all future issues will do justice to her memory. She was always very proud of the Journal as the official publication of the European Society for Pediatric Allergy & Clinical Immunology, to which she was devoted. Our first paper is following a line started by Dr Miceli Sopo in the previous issue in scrutinizing the methodology for studying cord blood T‐cell reactivity ( 1 ). Dr Sopo pleaded for a more rigorous standardization of methodology. Matthias Kopp and colleagues have specifically investigated the influence of cell concentration on proliferation of T cells in response to a number of common allergens and interleukin (IL)‐2. Clearly background activity fell with decreasing cell concentrations, but this occurred to a lesser extent in response to stimulation. Thus lower cell numbers unmasked T‐cell reactivity, which has led the authors to suggest a lower concentration of cells per well for proliferation experiments than has formerly been employed.

Journal

Pediatric Allergy and Immunology – Wiley

Published: Feb 1, 2000

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