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In This Issue

In This Issue ISSN 0905-6517 In This Issue In the first Issue of 1998, the front page illustration (prepared by Dr. Cathy Jones, Child Health, Southampton) showed a stunning microscope section through a chorionic villus of the placenta. It demonstrated the remarkably close proximity of maternal and fetal circulations and illustrated the importance that we attach to fetal life in the ontogeny of immune responsiveness and allergy. In the second Issue, we show a confocal microscrope picture of neutrophils with phagocytosed fluorescent Staphylococcus aureus (prepared by Ann Mander, Child Health, Southampton). This emphasises that we are also interested in the immunology of infection. It is remarkable that some neutrophils are capable of phagocytosing large numbers of Staphylococcus aureus while many others appear unable to phagocytose organisms. Are these immature or post-mature cells and can they be recruited by any form of stimulation to improve organism elimination? This may be a fruitful area for study. Our asthma series, begun in Issue 1, is continued with an article by yours truly. The relationship between bronchial hyperresponsiveness, allergy and airway inflammation is complex and remains unresolved. The article presents a confusogram which will hopefully encourage others to do further research in this area to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Allergy and Immunology Wiley

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Publisher
Wiley
Copyright
Copyright © 1998 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0905-6157
eISSN
1399-3038
DOI
10.1111/j.1399-3038.1998.tb00303.x
Publisher site
See Article on Publisher Site

Abstract

ISSN 0905-6517 In This Issue In the first Issue of 1998, the front page illustration (prepared by Dr. Cathy Jones, Child Health, Southampton) showed a stunning microscope section through a chorionic villus of the placenta. It demonstrated the remarkably close proximity of maternal and fetal circulations and illustrated the importance that we attach to fetal life in the ontogeny of immune responsiveness and allergy. In the second Issue, we show a confocal microscrope picture of neutrophils with phagocytosed fluorescent Staphylococcus aureus (prepared by Ann Mander, Child Health, Southampton). This emphasises that we are also interested in the immunology of infection. It is remarkable that some neutrophils are capable of phagocytosing large numbers of Staphylococcus aureus while many others appear unable to phagocytose organisms. Are these immature or post-mature cells and can they be recruited by any form of stimulation to improve organism elimination? This may be a fruitful area for study. Our asthma series, begun in Issue 1, is continued with an article by yours truly. The relationship between bronchial hyperresponsiveness, allergy and airway inflammation is complex and remains unresolved. The article presents a confusogram which will hopefully encourage others to do further research in this area to

Journal

Pediatric Allergy and ImmunologyWiley

Published: May 1, 1998

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