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Even though the armamentarium of options available to the interventional cardiologist has expanded over the recent past, there are still many complications that pose problems. Many of these complications stem from underlying mechanisms that are common to the spectrum of available procedures. Before discussing specific procedures and their related complications, basic information regarding these underlying mechanisms is discussed. This is fundamental to a good understanding of the specific details in the sections that follow. Abrupt Closure Abrupt closure is defined as total or subtotal coronary occlusion associated with clinical evidence of ischemia (Fig. 19). Abrupt closure is associated with mainly due a high risk of morbidity and rn~rtalityâ~â to the increase in myocardial infarction (MI) and the need for emergency coronary artery bypass surgery (CABG) associated with this complication. This entity typically occurs in the catheterization laboratory.152,153 Several different pathophysiological mechanisms have been implicated in abrupt closure, including thrombosis, vascular dissection at the treatment site (Fig. 19), guiding catheter injury of the ostium, and vascular perf0rati0n.l~~ Supported in part by Womenâs League for Medical Research, Albert Einstein Medical Center. Address for reprints: Moms N. Kotler, M.D., Albert Einstein Medical Center, 363 Klein Professional Building, 5401 Old York Road,
Journal of Interventional Cardiology – Wiley
Published: Oct 1, 1999
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